Min-Ho Kim Lab:Research

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Research goal The research goal of our laboratory is to (1) understand molecular and cellular mechanisms by which local inflammatory environmental cues alter phenotypic switch of tissue infiltrating innate immune cells and these cells functionally interact with endogenous or exogenously implanted mesenchymal stem cells (MSCs), and (2) develop selective strategy to engineer microenvironmental cues towards tissue regeneration by utilizing micro/nano-engineered biomaterials that enable spatio-temporal control of inflammatory response. To achieve this goal, we combine interdisciplinary approaches of immuno-biology, stem cell biology, cellular and tissue engineering, and nano-bioengineering.

Welcome to the Min-Ho Kim's research group at Kent State University The major research interests in our laboratory are to (1) understand biological mechanism by which immune cell trafficking contributes to the pathogenesis of chronic inflammatory diseases, (2) apply micro/nano-engineered biomaterials to precisely tune inflammatory environmental cues, and (3) thereby develop clinically feasible therapeutics to promote the resolution of non-healing chronic wounds. Our laboratory utilizes and combines interdisciplinary approaches of immuno-biology, stem cell biology, cellular and tissue engineering, and nano-bioengineering.

Current Research Projects Macrophage polarization on therapeutic potential of mesenchymal stem cells (MSCs). Targeted magnetic nanoparticle thermotherapy for the resolution of biofilm infection in diabetic wounds. Magnetically responsive injectable microgels for stem cell and tissue engineering. Nanoengineered biomaterial scaffold for immunomodulation.

Research Collaborators Prof. Chris Malcuit (Kent State) Prof. Chanjoong Kim (Liquid Crystal Institute, Kent State) Prof. Fayez Safadi (NEOMED) Prof. Sonping Huang (Kent State) Prof. Deok-Ho Kim (University of Washington) Joseph Nayfach (Qteris, Inc.)

Research Support Farris Family Innovation Award Kent State Postdoc Seed Program Award Kent State Start-up Fund