Minion Lab - Revision history

Andrew C. Petersen at 04:46, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 04:46:47 GMT

←Older revision		Revision as of 04:46, 16 February 2011
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-	I'm working on it ... but until then:	+	[[user: Andrew C. Petersen \| I'm]] working on it ... but until then:

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Andrew C. Petersen at 04:45, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 04:45:14 GMT

←Older revision		Revision as of 04:45, 16 February 2011
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		+	[[Minion_Lab:Lab_Group\| Lab Group]]

	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]		[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]

Andrew C. Petersen at 03:48, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 03:48:43 GMT

←Older revision		Revision as of 03:48, 16 February 2011
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	This laboratory has focused its efforts on molecular mechanisms of mycoplasmal pathogenesis for many years. To this end, we have developed genetic systems that can be used to identify and analyze virulence factors (Tn4001, integrative vectors, reporter constructs and cloning systems). We have also identified and studied membrane activities that might be involved in virulence (nucleases and hemolysins). Our more recent studies in mycoplasmas have focused on the cilium adhesin of ''Mycoplasma hyopneumoniae'', genomic sequencing of ''Mycoplasma hyopneumoniae'', and the development of recombinant vaccines against ''M. hyopneumoniae''. We have also constructed and validated a microarray for ''M. hyopneumoniae'' to study transcriptional responses to environmental changes and better understand gene regulation. Recently, we have also developed projects with other bacterial pathogens important either to food safety or biodefense. Most notably of these are ongoing studies on the persistence of ''E. coli'' O157:H7 in the ruminant focusing on biofilm development and transcription regulation. We also have a biodefense project on vaccine development with ''Yersinia pestis''.		This laboratory has focused its efforts on molecular mechanisms of mycoplasmal pathogenesis for many years. To this end, we have developed genetic systems that can be used to identify and analyze virulence factors (Tn4001, integrative vectors, reporter constructs and cloning systems). We have also identified and studied membrane activities that might be involved in virulence (nucleases and hemolysins). Our more recent studies in mycoplasmas have focused on the cilium adhesin of ''Mycoplasma hyopneumoniae'', genomic sequencing of ''Mycoplasma hyopneumoniae'', and the development of recombinant vaccines against ''M. hyopneumoniae''. We have also constructed and validated a microarray for ''M. hyopneumoniae'' to study transcriptional responses to environmental changes and better understand gene regulation. Recently, we have also developed projects with other bacterial pathogens important either to food safety or biodefense. Most notably of these are ongoing studies on the persistence of ''E. coli'' O157:H7 in the ruminant focusing on biofilm development and transcription regulation. We also have a biodefense project on vaccine development with ''Yersinia pestis''.
		+
		+	* Mycoplasma Genetic Systems and Reporter Vectors
		+	* M. hyopneumoniae adherence to swine cilia
		+	* Recombinant Vaccines
		+	* Mycoplasma Genomic Sequencing Projects (M. hyopneumoniae)
		+	* Microarrays
		+	* Persistence of E. coli 0157:H7 in ruminants
		+	* Molecular mechanisms of biofilm formation in E. coli O157:H7
		+	* Quorum sensing in Yersinia pestis and development of a single dose vaccine

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	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]		[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]
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		+	[http://vetmed.iastate.edu/vmpm Department of Veterinary Microbiology and Preventive Medicine]
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		+	[http://www.iastate.edu/ Iowa State University]

Andrew C. Petersen at 03:31, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 03:31:02 GMT

←Older revision		Revision as of 03:31, 16 February 2011
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	I'm working on it ... but until then:		I'm working on it ... but until then:
		+
		+	----
		+
		+	This laboratory has focused its efforts on molecular mechanisms of mycoplasmal pathogenesis for many years. To this end, we have developed genetic systems that can be used to identify and analyze virulence factors (Tn4001, integrative vectors, reporter constructs and cloning systems). We have also identified and studied membrane activities that might be involved in virulence (nucleases and hemolysins). Our more recent studies in mycoplasmas have focused on the cilium adhesin of ''Mycoplasma hyopneumoniae'', genomic sequencing of ''Mycoplasma hyopneumoniae'', and the development of recombinant vaccines against ''M. hyopneumoniae''. We have also constructed and validated a microarray for ''M. hyopneumoniae'' to study transcriptional responses to environmental changes and better understand gene regulation. Recently, we have also developed projects with other bacterial pathogens important either to food safety or biodefense. Most notably of these are ongoing studies on the persistence of ''E. coli'' O157:H7 in the ruminant focusing on biofilm development and transcription regulation. We also have a biodefense project on vaccine development with ''Yersinia pestis''.
		+
		+	----

	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]		[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]

Andrew C. Petersen at 03:26, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 03:26:26 GMT

←Older revision		Revision as of 03:26, 16 February 2011
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-	I'm working on it ... but until then	+	I'm working on it ... but until then:

	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]		[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]

Andrew C. Petersen at 03:26, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 03:26:14 GMT

←Older revision		Revision as of 03:26, 16 February 2011
Line 1:		Line 1:
	I'm working on it ... but until then		I'm working on it ... but until then
		+
	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]		[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]

Andrew C. Petersen at 03:25, 16 February 2011

Andrew C. Petersen — Wed, 16 Feb 2011 03:25:31 GMT

←Older revision		Revision as of 03:25, 16 February 2011
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-	I'm working on it	+	I'm working on it ... but until then
		+	[http://vetmed.iastate.edu/research/labs/fcminion Minion Lab Homepage]

Andrew C. Petersen: New page: I'm working on it

Andrew C. Petersen — Wed, 16 Feb 2011 02:44:03 GMT

New page: I'm working on it

New page

I'm working on it