NEUROBIO:FT

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(Seminário 8: Esclerose Múltipla)
 
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''Seminário 1: Traumatismo Crânio-Encefálico''
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=Seminário 1: Traumatismo Crânio-Encefálico=
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* Apresentação do tema
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* Apresentação do tema: [https://www.dropbox.com/s/gqf7g2mppxqgve4/TRAUMA.pptx Slides]
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* Blennow K, Hardy J, Zetterberg H [https://www.dropbox.com/sh/77d2m8kfnzi8k26/t-53Nw3I5c The Neuropathology and Neurobiology of Traumatic Brain Injury]. Neuron 2011, 76(5):886-899
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* Bibliografia principal:
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* North SH, Shriver-Lake LC, Taitt CR, Ligler FS [https://www.dropbox.com/sh/77d2m8kfnzi8k26/zhRo3ZOL-5/Rapid%20Analytical%20Methods%20for%20On-Site%20Triage%20for%20Traumatic%20Brain%20Injury.pdf Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury] Annu Rev Anal Chem, 2012(5):35-56.
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# Blennow K, Hardy J, Zetterberg H [https://www.dropbox.com/s/2wtuwebwm7ej8te/The%20Neuropathology%20and%20Neurobiology%20of%20Traumatic%20Brain%20Injury.pdf The Neuropathology and Neurobiology of Traumatic Brain Injury]. Neuron 2012, 76(5):886-899
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* Bibliografia complementar:
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# North SH, Shriver-Lake LC, Taitt CR, Ligler FS [https://www.dropbox.com/s/o4fs1c0sahl0biw/Rapid%20Analytical%20Methods%20for%20On-Site%20Triage%20for%20Traumatic%20Brain%20Injury.pdf Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury] Annu Rev Anal Chem, 2012(5):35-56.
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# Bélanger M, Allaman I, Magistretti PJ. [https://www.dropbox.com/s/140ztadf92ul8e7/Brain%20Energy%20Metabolism-%20Focus%20on%20Astrocyte-Neuron%20Metabolic%20Cooperation.pdf Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation]. Cell Metab. 2011 Dec 7;14(6):724-738.
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# Allaman I, Bélanger M, Magistretti PJ. [https://www.dropbox.com/s/iwp53qwdkhjd2fz/Astrocyte%E2%80%93neuron%20metabolic%20relationships.pdf Astrocyte-neuron metabolic relationships: for better and for worse]. Trends Neurosci. 2011, 34(2):76-87
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# Dreier JP. [https://www.dropbox.com/s/q0au6fy26g6la5y/The%20role%20of%20spreading%20depression%2C%20spreading%20depolarization%20and%20spreading%20ischemia%20in%20neurological%20disease.pdf The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease]. Nat Med. 2011, 17(4):439-447
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# Lee JM, Zipfel GJ, Choi DW.[https://www.dropbox.com/s/q0au6fy26g6la5y/The%20role%20of%20spreading%20depression%2C%20spreading%20depolarization%20and%20spreading%20ischemia%20in%20neurological%20disease.pdf The changing landscape of ischaemic brain injury mechanisms]. Nature. 1999, 24;399(6738 Suppl):A7-14.
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''Seminário 2: Acidente Vascular Cerebral''
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<br>
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* Apresentação do tema
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=Seminário 2: Tumor Cerebral=
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* Apresentação do tema: [https://www.dropbox.com/s/2nsm21b92o2rrc5/TUMOR%20CEREBRAL.pptx Slides]
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<!-- Replace everything above this line with information about your course. -->
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* Bibliografia geral
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# Peto J. [https://www.dropbox.com/s/8fso17ph8gq1lht/Cancer%20epidemiology%20in%20the%20last%20century%20and%20the%20next%20decade.pdf Cancer epidemiology in the last century and the next decade]. Nature. 2001 May 17;411:390-5.
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# The patient education institute. [http://www.nlm.nih.gov/medlineplus/tutorials/braincancer/oc119104.pdf Brain Cancer]. Última revisão 01/10/2011
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# Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. [http://www.ncbi.nlm.nih.gov/books/NBK26816/ Finding the Cancer-Critical Genes]
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# Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. [http://www.ncbi.nlm.nih.gov/books/NBK26902/ The Molecular Basis of Cancer-Cell Behavior]
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# Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. [http://www.ncbi.nlm.nih.gov/books/NBK21662/ Proto-Oncogenes and Tumor-Suppressor Genes]
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# Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. [http://www.ncbi.nlm.nih.gov/books/NBK21526/ Mutations Causing Loss of Cell-Cycle Control]
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# Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. [http://www.ncbi.nlm.nih.gov/books/NBK21551/ Mutations Affecting Genome Stability]
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<br>
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=Seminário 3: Acidente Vascular Cerebral=
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* Apresentação do tema [https://www.dropbox.com/sh/jisyve47zgqw33q/yuYVzpCwAI Pasta]
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#Jackson SP. [https://www.dropbox.com/sh/jisyve47zgqw33q/yuYVzpCwAI  Arterial thrombosis-insidious, unpredictable and deadly]. Nat Med. 2011 Nov 7;17(11):1423-36.
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#Culmsee C, Krieglstein J. [https://www.dropbox.com/sh/jisyve47zgqw33q/yuYVzpCwAI  Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies] EMBO Rep. 2007 Feb;8(2):129-33.
 +
#Saeed SA, Shad KF, Saleem T, Javed F, Khan MU. [https://www.dropbox.com/sh/jisyve47zgqw33q/yuYVzpCwAI  Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke]. Exp Brain Res. 2007 Sep;182(1):1-10.
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<br>
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=Seminário 4: Paralisia Cerebral=
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* Apresentação do tema [https://www.dropbox.com/s/hppm7311utmq7u0/PC.pptx Slides]
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#Fleiss B, Gressens P. [https://www.dropbox.com/s/rinljr8vgv4zoe1/Tertiary%20mechanisms%20of%20brain%20damage.pdf Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?] Lancet Neurol (2012);11:556-566.
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#Aisen ML, et al. [https://www.dropbox.com/s/o7z50zcizh67f3k/Cerebral%20palsy-%20clinical%20care%20and%20neurological%20rehabilitation..pdf Cerebral palsy: clinical care and neurological rehabilitation]. Lancet Neurol (2011); 10: 844–852
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#Boksa P. [https://www.dropbox.com/s/9dngt2u67hz763o/1-s2.0-S0889159110000589-main.pdf Effects of prenatal infection on brain development and behavior: A review of findings from animal models]. Brain, Behavior, and Immunity (2010) 24: 881–897
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#Babcock MA, et al. [https://www.dropbox.com/s/lhtfxqftp7huglc/Injury%20to%20the%20preterm%20brain%20and%20cerebral%20palsy-%20clinical%20aspects%2C%20molecular%20mechanisms.pdf Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions]. J Child Neurol (2009) 24:1064-1084
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#Kaindl AM, Favrais G, Gressens P. [https://www.dropbox.com/s/v3a6vzwqrxlaptf/Molecular%20Mechanisms%20Involved%20in%20Injury%20to%20the%20Preterm%20Brain.pdf Molecular mechanisms involved in injury to the preterm brain]. J Child Neurol (2009) 24:1112-1118.
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<br>
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=Seminário 5: Infecções=
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* Apresentação do tema [https://www.dropbox.com/s/evxyela1wzs3yqo/NB_FT_INFECTION.pptx Slides]
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#Kim SK. [https://www.dropbox.com/s/51ckg31ayokyviu/Pathogenesis%20of%20bacterial%20meningitis-%20from%20bacteraemia%20to%20neuronal%20injury.pdf Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury]. Nature Reviews Neuroscience (2003) 4:376-385.
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#van den Pol AN. [https://www.dropbox.com/s/8f3c2bqyq9sj68h/Viral%20infections%20in%20the%20developing%20and%20mature%20brain.pdf Viral infections in the developing and mature brain]. Trends in Neuroscience (2006) 29:398-406.
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=Seminário 6: Parkinson=
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* Apresentação do tema [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Slides]
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#Bandopadhyay R, de Belleroche J. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Role of the ubiquitin proteasome system in Parkinson's disease]. Trends in Molecular Medicine (2010) 16:27-36.
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#Lim KL, Tan JMM. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Role of the ubiquitin proteasome system in Parkinson's disease]. BMC Biochemistry (2007) 8(Suppl 1):S13
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#Dunnett SB, Bjorklund A. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Prospects for new restorative and neuroprotective treatments in Parkinson’s disease]. Nature (1999) 399 (Supp):A32-A39.
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<br>
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=Seminário 7: Distonias=
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* Apresentação do tema [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY Slides]
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#Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The pathophysiological basis of dystonias]. Nature Reviews Neuroscience (2008) 9: 222-234.
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# Tanabe LE, Kim CE, Alagem N, Dauer WT [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY Primary dystonia: molecules and mechanisms]. Nature Reviews Neurology (2009) 5: 598–609.
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# Neychev VK, Gross RE, Lehéricy S, Hess EJ, Jinnah HA [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The functional neuroanatomy of dystonia]. Neurobiology of Disease (2011) 42:185-201.
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# Calderon DP, Fremont R, Kraenzlin F, Khodakhah K [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The neural substrates of rapid-onset Dystonia-Parkinsonism]. Nature Neuroscience (2011) 14:357-365.
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<br>
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=Seminário 8: Esclerose Múltipla=
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* Apresentação do tema [https://www.dropbox.com/s/al1jdkwspa6wx9i/NB_FT_EM.ppt Slides]
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#Hemmer B, Archelos JJ, Hartung HP. [https://www.dropbox.com/s/lezo0u4tn8cyf9a/Hemmer%202002.pdf New concepts in the immunopathogenesis of multiple sclerosis]. Nat Rev Neurosci (2002) 3(4):291-301.
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#Frohman EM, Racke MK, Raine CS. [https://www.dropbox.com/s/0hisiuvsp5jnc35/Froman%20review%20MS%20pathogenesis.pdf Multiple sclerosis-the plaque and its pathogenesis]. N Engl J Med (2006) 354(9):942-55.
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#Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L.[https://www.dropbox.com/s/9308r3uo5y3auok/Multiple%20sclerosis%20MHC%20associations%20and%20therapeutic%20implications.pdf Multiple sclerosis: MHC associations and therapeutic implications]. Expert Rev Mol Med (2005) 7(3):1-17.
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#Venken K, Hellings N, Liblau R, Stinissen P. [https://www.dropbox.com/s/90humqh7muydw9p/Disturbed%20regulatory%20T%20cell%20homeostasis%20in%20multiple%20sclerosis.pdf Disturbed regulatory T cell homeostasis in multiple sclerosis]. Trends Mol Med (2010) 16(2):58-68.
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Current revision

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Contents

Seminário 1: Traumatismo Crânio-Encefálico

  • Apresentação do tema: Slides
  • Bibliografia principal:
  1. Blennow K, Hardy J, Zetterberg H The Neuropathology and Neurobiology of Traumatic Brain Injury. Neuron 2012, 76(5):886-899
  • Bibliografia complementar:
  1. North SH, Shriver-Lake LC, Taitt CR, Ligler FS Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury Annu Rev Anal Chem, 2012(5):35-56.
  2. Bélanger M, Allaman I, Magistretti PJ. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab. 2011 Dec 7;14(6):724-738.
  3. Allaman I, Bélanger M, Magistretti PJ. Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci. 2011, 34(2):76-87
  4. Dreier JP. The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med. 2011, 17(4):439-447
  5. Lee JM, Zipfel GJ, Choi DW.The changing landscape of ischaemic brain injury mechanisms. Nature. 1999, 24;399(6738 Suppl):A7-14.


Seminário 2: Tumor Cerebral

  • Apresentação do tema: Slides
  • Bibliografia geral
  1. Peto J. Cancer epidemiology in the last century and the next decade. Nature. 2001 May 17;411:390-5.
  2. The patient education institute. Brain Cancer. Última revisão 01/10/2011
  3. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Finding the Cancer-Critical Genes
  4. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. The Molecular Basis of Cancer-Cell Behavior
  5. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Proto-Oncogenes and Tumor-Suppressor Genes
  6. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Causing Loss of Cell-Cycle Control
  7. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Affecting Genome Stability


Seminário 3: Acidente Vascular Cerebral

  • Apresentação do tema Pasta
  1. Jackson SP. Arterial thrombosis-insidious, unpredictable and deadly. Nat Med. 2011 Nov 7;17(11):1423-36.
  2. Culmsee C, Krieglstein J. Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies EMBO Rep. 2007 Feb;8(2):129-33.
  3. Saeed SA, Shad KF, Saleem T, Javed F, Khan MU. Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke. Exp Brain Res. 2007 Sep;182(1):1-10.


Seminário 4: Paralisia Cerebral

  • Apresentação do tema Slides
  1. Fleiss B, Gressens P. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy? Lancet Neurol (2012);11:556-566.
  2. Aisen ML, et al. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol (2011); 10: 844–852
  3. Boksa P. Effects of prenatal infection on brain development and behavior: A review of findings from animal models. Brain, Behavior, and Immunity (2010) 24: 881–897
  4. Babcock MA, et al. Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions. J Child Neurol (2009) 24:1064-1084
  5. Kaindl AM, Favrais G, Gressens P. Molecular mechanisms involved in injury to the preterm brain. J Child Neurol (2009) 24:1112-1118.


Seminário 5: Infecções

  • Apresentação do tema Slides
  1. Kim SK. Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury. Nature Reviews Neuroscience (2003) 4:376-385.
  2. van den Pol AN. Viral infections in the developing and mature brain. Trends in Neuroscience (2006) 29:398-406.


Seminário 6: Parkinson

  • Apresentação do tema Slides
  1. Bandopadhyay R, de Belleroche J. Role of the ubiquitin proteasome system in Parkinson's disease. Trends in Molecular Medicine (2010) 16:27-36.
  2. Lim KL, Tan JMM. Role of the ubiquitin proteasome system in Parkinson's disease. BMC Biochemistry (2007) 8(Suppl 1):S13
  3. Dunnett SB, Bjorklund A. Prospects for new restorative and neuroprotective treatments in Parkinson’s disease. Nature (1999) 399 (Supp):A32-A39.


Seminário 7: Distonias

  • Apresentação do tema Slides
  1. Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG The pathophysiological basis of dystonias. Nature Reviews Neuroscience (2008) 9: 222-234.
  2. Tanabe LE, Kim CE, Alagem N, Dauer WT Primary dystonia: molecules and mechanisms. Nature Reviews Neurology (2009) 5: 598–609.
  3. Neychev VK, Gross RE, Lehéricy S, Hess EJ, Jinnah HA The functional neuroanatomy of dystonia. Neurobiology of Disease (2011) 42:185-201.
  4. Calderon DP, Fremont R, Kraenzlin F, Khodakhah K The neural substrates of rapid-onset Dystonia-Parkinsonism. Nature Neuroscience (2011) 14:357-365.


Seminário 8: Esclerose Múltipla

  • Apresentação do tema Slides
  1. Hemmer B, Archelos JJ, Hartung HP. New concepts in the immunopathogenesis of multiple sclerosis. Nat Rev Neurosci (2002) 3(4):291-301.
  2. Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med (2006) 354(9):942-55.
  3. Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L.Multiple sclerosis: MHC associations and therapeutic implications. Expert Rev Mol Med (2005) 7(3):1-17.
  4. Venken K, Hellings N, Liblau R, Stinissen P. Disturbed regulatory T cell homeostasis in multiple sclerosis. Trends Mol Med (2010) 16(2):58-68.
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