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=Seminário 1: Traumatismo Crânio-Encefálico=
=Seminário 1: Traumatismo Crânio-Encefálico=
* Apresentação do tema: [https://www.dropbox.com/s/pn3j4711t99t428/TRAUMA.pptx Slides]
* Apresentação do tema: [https://www.dropbox.com/s/gqf7g2mppxqgve4/TRAUMA.pptx Slides]
* Bibliografia principal:
* Bibliografia principal:
# Blennow K, Hardy J, Zetterberg H [https://www.dropbox.com/s/w8q86yiw1lbhrpq/The%20Neuropathology%20and%20Neurobiology%20of%20Traumatic%20Brain%20Injury.pdf The Neuropathology and Neurobiology of Traumatic Brain Injury]. Neuron 2012, 76(5):886-899
# Blennow K, Hardy J, Zetterberg H [https://www.dropbox.com/s/2wtuwebwm7ej8te/The%20Neuropathology%20and%20Neurobiology%20of%20Traumatic%20Brain%20Injury.pdf The Neuropathology and Neurobiology of Traumatic Brain Injury]. Neuron 2012, 76(5):886-899
* Bibliografia complementar:
* Bibliografia complementar:
# North SH, Shriver-Lake LC, Taitt CR, Ligler FS [https://www.dropbox.com/sh/77d2m8kfnzi8k26/zhRo3ZOL-5/Rapid%20Analytical%20Methods%20for%20On-Site%20Triage%20for%20Traumatic%20Brain%20Injury.pdf Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury] Annu Rev Anal Chem, 2012(5):35-56.
# North SH, Shriver-Lake LC, Taitt CR, Ligler FS [https://www.dropbox.com/s/o4fs1c0sahl0biw/Rapid%20Analytical%20Methods%20for%20On-Site%20Triage%20for%20Traumatic%20Brain%20Injury.pdf Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury] Annu Rev Anal Chem, 2012(5):35-56.
# Bélanger M, Allaman I, Magistretti PJ. [https://www.dropbox.com/s/i9zewu44uhqpkyr/Brain%20Energy%20Metabolism-%20Focus%20on%20Astrocyte-Neuron%20Metabolic%20Cooperation.pdf Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation]. Cell Metab. 2011 Dec 7;14(6):724-738.
# Bélanger M, Allaman I, Magistretti PJ. [https://www.dropbox.com/s/140ztadf92ul8e7/Brain%20Energy%20Metabolism-%20Focus%20on%20Astrocyte-Neuron%20Metabolic%20Cooperation.pdf Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation]. Cell Metab. 2011 Dec 7;14(6):724-738.
# Allaman I, Bélanger M, Magistretti PJ. [https://www.dropbox.com/s/7w5gh1si41vbfgd/Astrocyte%E2%80%93neuron%20metabolic%20relationships.pdf Astrocyte-neuron metabolic relationships: for better and for worse]. Trends Neurosci. 2011, 34(2):76-87
# Allaman I, Bélanger M, Magistretti PJ. [https://www.dropbox.com/s/iwp53qwdkhjd2fz/Astrocyte%E2%80%93neuron%20metabolic%20relationships.pdf Astrocyte-neuron metabolic relationships: for better and for worse]. Trends Neurosci. 2011, 34(2):76-87
# Dreier JP. [https://www.dropbox.com/s/3ipn7neyoh3h3y5/The%20role%20of%20spreading%20depression%2C%20spreading%20depolarization%20and%20spreading%20ischemia%20in%20neurological%20disease.pdf The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease]. Nat Med. 2011, 17(4):439-447
# Dreier JP. [https://www.dropbox.com/s/q0au6fy26g6la5y/The%20role%20of%20spreading%20depression%2C%20spreading%20depolarization%20and%20spreading%20ischemia%20in%20neurological%20disease.pdf The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease]. Nat Med. 2011, 17(4):439-447
# Lee JM, Zipfel GJ, Choi DW.[https://www.dropbox.com/s/liqyzyhuwavkctw/The%20changing%20landscape%20of%20ischaemic%20brain%20injury%20mechanisms.pdf The changing landscape of ischaemic brain injury mechanisms]. Nature. 1999, 24;399(6738 Suppl):A7-14.
# Lee JM, Zipfel GJ, Choi DW.[https://www.dropbox.com/s/q0au6fy26g6la5y/The%20role%20of%20spreading%20depression%2C%20spreading%20depolarization%20and%20spreading%20ischemia%20in%20neurological%20disease.pdf The changing landscape of ischaemic brain injury mechanisms]. Nature. 1999, 24;399(6738 Suppl):A7-14.


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=Seminário 2: Tumor Cerebral=
=Seminário 2: Tumor Cerebral=
* Apresentação do tema: [https://www.dropbox.com/s/2nsm21b92o2rrc5/TUMOR%20CEREBRAL.pptx Slides]
* Apresentação do tema: [https://www.dropbox.com/s/2nsm21b92o2rrc5/TUMOR%20CEREBRAL.pptx Slides]
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=Seminário 4: Paralisia Cerebral=
=Seminário 4: Paralisia Cerebral=
* Apresentação do tema [https://www.dropbox.com/s/hppm7311utmq7u0/PC.pptx SLIDES]
* Apresentação do tema [https://www.dropbox.com/s/hppm7311utmq7u0/PC.pptx Slides]
#Fleiss B, Gressens P. [https://www.dropbox.com/s/rinljr8vgv4zoe1/Tertiary%20mechanisms%20of%20brain%20damage.pdf Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?] Lancet Neurol (2012);11:556-66.  
#Fleiss B, Gressens P. [https://www.dropbox.com/s/rinljr8vgv4zoe1/Tertiary%20mechanisms%20of%20brain%20damage.pdf Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?] Lancet Neurol (2012);11:556-566.  
#Aisen ML, et al. [https://www.dropbox.com/s/o7z50zcizh67f3k/Cerebral%20palsy-%20clinical%20care%20and%20neurological%20rehabilitation..pdf Cerebral palsy: clinical care and neurological rehabilitation]. Lancet Neurol (2011); 10: 844–52
#Aisen ML, et al. [https://www.dropbox.com/s/o7z50zcizh67f3k/Cerebral%20palsy-%20clinical%20care%20and%20neurological%20rehabilitation..pdf Cerebral palsy: clinical care and neurological rehabilitation]. Lancet Neurol (2011); 10: 844–852
#Boksa P. [https://www.dropbox.com/s/9dngt2u67hz763o/1-s2.0-S0889159110000589-main.pdf Effects of prenatal infection on brain development and behavior: A review of findings from animal models]. Brain, Behavior, and Immunity (2010) 24: 881–897
#Boksa P. [https://www.dropbox.com/s/9dngt2u67hz763o/1-s2.0-S0889159110000589-main.pdf Effects of prenatal infection on brain development and behavior: A review of findings from animal models]. Brain, Behavior, and Immunity (2010) 24: 881–897
#Babcock MA, et al. [https://www.dropbox.com/s/lhtfxqftp7huglc/Injury%20to%20the%20preterm%20brain%20and%20cerebral%20palsy-%20clinical%20aspects%2C%20molecular%20mechanisms.pdf Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions]. J Child Neurol (2009) 24:1064-84
#Babcock MA, et al. [https://www.dropbox.com/s/lhtfxqftp7huglc/Injury%20to%20the%20preterm%20brain%20and%20cerebral%20palsy-%20clinical%20aspects%2C%20molecular%20mechanisms.pdf Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions]. J Child Neurol (2009) 24:1064-1084
#Kaindl AM, Favrais G, Gressens P. [https://www.dropbox.com/s/v3a6vzwqrxlaptf/Molecular%20Mechanisms%20Involved%20in%20Injury%20to%20the%20Preterm%20Brain.pdf Molecular mechanisms involved in injury to the preterm brain]. J Child Neurol (2009) 24:1112-1118.
<br>


[https://www.dropbox.com/s/v3a6vzwqrxlaptf/Molecular%20Mechanisms%20Involved%20in%20Injury%20to%20the%20Preterm%20Brain.pdf ]
=Seminário 5: Infecções=
* Apresentação do tema [https://www.dropbox.com/s/evxyela1wzs3yqo/NB_FT_INFECTION.pptx Slides]
#Kim SK. [https://www.dropbox.com/s/51ckg31ayokyviu/Pathogenesis%20of%20bacterial%20meningitis-%20from%20bacteraemia%20to%20neuronal%20injury.pdf Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury]. Nature Reviews Neuroscience (2003) 4:376-385.
#van den Pol AN. [https://www.dropbox.com/s/8f3c2bqyq9sj68h/Viral%20infections%20in%20the%20developing%20and%20mature%20brain.pdf Viral infections in the developing and mature brain]. Trends in Neuroscience (2006) 29:398-406.






=Seminário 6: Parkinson=
* Apresentação do tema [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Slides]
#Bandopadhyay R, de Belleroche J. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Role of the ubiquitin proteasome system in Parkinson's disease]. Trends in Molecular Medicine (2010) 16:27-36.
#Lim KL, Tan JMM. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Role of the ubiquitin proteasome system in Parkinson's disease]. BMC Biochemistry (2007) 8(Suppl 1):S13
#Dunnett SB, Bjorklund A. [https://www.dropbox.com/sh/xh2c08qgvmttt38/AgPPAwowd6 Prospects for new restorative and neuroprotective treatments in Parkinson’s disease]. Nature (1999) 399 (Supp):A32-A39.
<br>
=Seminário 7: Distonias=
* Apresentação do tema [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY Slides]
#Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The pathophysiological basis of dystonias]. Nature Reviews Neuroscience (2008) 9: 222-234.
# Tanabe LE, Kim CE, Alagem N, Dauer WT [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY Primary dystonia: molecules and mechanisms]. Nature Reviews Neurology (2009) 5: 598–609.
# Neychev VK, Gross RE, Lehéricy S, Hess EJ, Jinnah HA [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The functional neuroanatomy of dystonia]. Neurobiology of Disease (2011) 42:185-201.
# Calderon DP, Fremont R, Kraenzlin F, Khodakhah K [https://www.dropbox.com/sh/ex4zg3ik3f3xakb/WWvlcMOHAY The neural substrates of rapid-onset Dystonia-Parkinsonism]. Nature Neuroscience (2011) 14:357-365.
<br>
=Seminário 8: Esclerose Múltipla=
* Apresentação do tema [https://www.dropbox.com/s/al1jdkwspa6wx9i/NB_FT_EM.ppt Slides]
#Hemmer B, Archelos JJ, Hartung HP. [https://www.dropbox.com/s/lezo0u4tn8cyf9a/Hemmer%202002.pdf New concepts in the immunopathogenesis of multiple sclerosis]. Nat Rev Neurosci (2002) 3(4):291-301.
#Frohman EM, Racke MK, Raine CS. [https://www.dropbox.com/s/0hisiuvsp5jnc35/Froman%20review%20MS%20pathogenesis.pdf Multiple sclerosis-the plaque and its pathogenesis]. N Engl J Med (2006) 354(9):942-55.
#Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L.[https://www.dropbox.com/s/9308r3uo5y3auok/Multiple%20sclerosis%20MHC%20associations%20and%20therapeutic%20implications.pdf Multiple sclerosis: MHC associations and therapeutic implications]. Expert Rev Mol Med (2005) 7(3):1-17.
#Venken K, Hellings N, Liblau R, Stinissen P. [https://www.dropbox.com/s/90humqh7muydw9p/Disturbed%20regulatory%20T%20cell%20homeostasis%20in%20multiple%20sclerosis.pdf Disturbed regulatory T cell homeostasis in multiple sclerosis]. Trends Mol Med (2010) 16(2):58-68.


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Latest revision as of 03:52, 11 June 2013

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Seminário 1: Traumatismo Crânio-Encefálico

  • Apresentação do tema: Slides
  • Bibliografia principal:
  1. Blennow K, Hardy J, Zetterberg H The Neuropathology and Neurobiology of Traumatic Brain Injury. Neuron 2012, 76(5):886-899
  • Bibliografia complementar:
  1. North SH, Shriver-Lake LC, Taitt CR, Ligler FS Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury Annu Rev Anal Chem, 2012(5):35-56.
  2. Bélanger M, Allaman I, Magistretti PJ. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab. 2011 Dec 7;14(6):724-738.
  3. Allaman I, Bélanger M, Magistretti PJ. Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci. 2011, 34(2):76-87
  4. Dreier JP. The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med. 2011, 17(4):439-447
  5. Lee JM, Zipfel GJ, Choi DW.The changing landscape of ischaemic brain injury mechanisms. Nature. 1999, 24;399(6738 Suppl):A7-14.


Seminário 2: Tumor Cerebral

  • Apresentação do tema: Slides
  • Bibliografia geral
  1. Peto J. Cancer epidemiology in the last century and the next decade. Nature. 2001 May 17;411:390-5.
  2. The patient education institute. Brain Cancer. Última revisão 01/10/2011
  3. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Finding the Cancer-Critical Genes
  4. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. The Molecular Basis of Cancer-Cell Behavior
  5. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Proto-Oncogenes and Tumor-Suppressor Genes
  6. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Causing Loss of Cell-Cycle Control
  7. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Affecting Genome Stability


Seminário 3: Acidente Vascular Cerebral

  • Apresentação do tema Pasta
  1. Jackson SP. Arterial thrombosis-insidious, unpredictable and deadly. Nat Med. 2011 Nov 7;17(11):1423-36.
  2. Culmsee C, Krieglstein J. Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies EMBO Rep. 2007 Feb;8(2):129-33.
  3. Saeed SA, Shad KF, Saleem T, Javed F, Khan MU. Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke. Exp Brain Res. 2007 Sep;182(1):1-10.


Seminário 4: Paralisia Cerebral

  1. Fleiss B, Gressens P. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy? Lancet Neurol (2012);11:556-566.
  2. Aisen ML, et al. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol (2011); 10: 844–852
  3. Boksa P. Effects of prenatal infection on brain development and behavior: A review of findings from animal models. Brain, Behavior, and Immunity (2010) 24: 881–897
  4. Babcock MA, et al. Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions. J Child Neurol (2009) 24:1064-1084
  5. Kaindl AM, Favrais G, Gressens P. Molecular mechanisms involved in injury to the preterm brain. J Child Neurol (2009) 24:1112-1118.


Seminário 5: Infecções

  1. Kim SK. Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury. Nature Reviews Neuroscience (2003) 4:376-385.
  2. van den Pol AN. Viral infections in the developing and mature brain. Trends in Neuroscience (2006) 29:398-406.


Seminário 6: Parkinson

  1. Bandopadhyay R, de Belleroche J. Role of the ubiquitin proteasome system in Parkinson's disease. Trends in Molecular Medicine (2010) 16:27-36.
  2. Lim KL, Tan JMM. Role of the ubiquitin proteasome system in Parkinson's disease. BMC Biochemistry (2007) 8(Suppl 1):S13
  3. Dunnett SB, Bjorklund A. Prospects for new restorative and neuroprotective treatments in Parkinson’s disease. Nature (1999) 399 (Supp):A32-A39.


Seminário 7: Distonias

  1. Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG The pathophysiological basis of dystonias. Nature Reviews Neuroscience (2008) 9: 222-234.
  2. Tanabe LE, Kim CE, Alagem N, Dauer WT Primary dystonia: molecules and mechanisms. Nature Reviews Neurology (2009) 5: 598–609.
  3. Neychev VK, Gross RE, Lehéricy S, Hess EJ, Jinnah HA The functional neuroanatomy of dystonia. Neurobiology of Disease (2011) 42:185-201.
  4. Calderon DP, Fremont R, Kraenzlin F, Khodakhah K The neural substrates of rapid-onset Dystonia-Parkinsonism. Nature Neuroscience (2011) 14:357-365.


Seminário 8: Esclerose Múltipla

  1. Hemmer B, Archelos JJ, Hartung HP. New concepts in the immunopathogenesis of multiple sclerosis. Nat Rev Neurosci (2002) 3(4):291-301.
  2. Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med (2006) 354(9):942-55.
  3. Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L.Multiple sclerosis: MHC associations and therapeutic implications. Expert Rev Mol Med (2005) 7(3):1-17.
  4. Venken K, Hellings N, Liblau R, Stinissen P. Disturbed regulatory T cell homeostasis in multiple sclerosis. Trends Mol Med (2010) 16(2):58-68.
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