NEUROBIO:FT

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Seminário 1: Traumatismo Crânio-Encefálico

  • Apresentação do tema: Slides
  • Bibliografia principal:
  1. Blennow K, Hardy J, Zetterberg H The Neuropathology and Neurobiology of Traumatic Brain Injury. Neuron 2012, 76(5):886-899
  • Bibliografia complementar:
  1. North SH, Shriver-Lake LC, Taitt CR, Ligler FS Rapid Analytical Methods for On-Site Triage for Traumatic Brain Injury Annu Rev Anal Chem, 2012(5):35-56.
  2. Bélanger M, Allaman I, Magistretti PJ. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab. 2011 Dec 7;14(6):724-738.
  3. Allaman I, Bélanger M, Magistretti PJ. Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci. 2011, 34(2):76-87
  4. Dreier JP. The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med. 2011, 17(4):439-447
  5. Lee JM, Zipfel GJ, Choi DW.The changing landscape of ischaemic brain injury mechanisms. Nature. 1999, 24;399(6738 Suppl):A7-14.


Seminário 2: Tumor Cerebral

  • Apresentação do tema: Slides
  • Bibliografia geral
  1. Peto J. Cancer epidemiology in the last century and the next decade. Nature. 2001 May 17;411:390-5.
  2. The patient education institute. Brain Cancer. Última revisão 01/10/2011
  3. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Finding the Cancer-Critical Genes
  4. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. The Molecular Basis of Cancer-Cell Behavior
  5. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Proto-Oncogenes and Tumor-Suppressor Genes
  6. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Causing Loss of Cell-Cycle Control
  7. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Mutations Affecting Genome Stability


Seminário 3: Acidente Vascular Cerebral

  • Apresentação do tema Pasta
  1. Jackson SP. Arterial thrombosis-insidious, unpredictable and deadly. Nat Med. 2011 Nov 7;17(11):1423-36.
  2. Culmsee C, Krieglstein J. Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies EMBO Rep. 2007 Feb;8(2):129-33.
  3. Saeed SA, Shad KF, Saleem T, Javed F, Khan MU. Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke. Exp Brain Res. 2007 Sep;182(1):1-10.


Seminário 4: Paralisia Cerebral

  1. Fleiss B, Gressens P. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy? Lancet Neurol (2012);11:556-566.
  2. Aisen ML, et al. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol (2011); 10: 844–852
  3. Boksa P. Effects of prenatal infection on brain development and behavior: A review of findings from animal models. Brain, Behavior, and Immunity (2010) 24: 881–897
  4. Babcock MA, et al. Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions. J Child Neurol (2009) 24:1064-1084
  5. Kaindl AM, Favrais G, Gressens P. Molecular mechanisms involved in injury to the preterm brain. J Child Neurol (2009) 24:1112-1118.


Seminário 5: Infecções

  1. Kim SK. Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury. Nature Reviews Neuroscience (2003) 4:376-385.
  2. van den Pol AN. Viral infections in the developing and mature brain. Trends in Neuroscience (2006) 29:398-406.


Seminário 6: Parkinson

  1. Bandopadhyay R, de Belleroche J. Role of the ubiquitin proteasome system in Parkinson's disease. Trends in Molecular Medicine (2010) 16:27-36.
  2. Lim KL, Tan JMM. Role of the ubiquitin proteasome system in Parkinson's disease. BMC Biochemistry (2007) 8(Suppl 1):S13
  3. Dunnett SB, Bjorklund A. Prospects for new restorative and neuroprotective treatments in Parkinson’s disease. Nature (1999) 399 (Supp):A32-A39.


Seminário 7: Distonias

  1. Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG The pathophysiological basis of dystonias. Nature Reviews Neuroscience (2008) 9: 222-234.
  2. Tanabe LE, Kim CE, Alagem N, Dauer WT Primary dystonia: molecules and mechanisms. Nature Reviews Neurology (2009) 5: 598–609.
  3. Neychev VK, Gross RE, Lehéricy S, Hess EJ, Jinnah HA The functional neuroanatomy of dystonia. Neurobiology of Disease (2011) 42:185-201.
  4. Calderon DP, Fremont R, Kraenzlin F, Khodakhah K The neural substrates of rapid-onset Dystonia-Parkinsonism. Nature Neuroscience (2011) 14:357-365.


Seminário 8: Esclerose Múltipla

  1. Hemmer B, Archelos JJ, Hartung HP. New concepts in the immunopathogenesis of multiple sclerosis. Nat Rev Neurosci (2002) 3(4):291-301.
  2. Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med (2006) 354(9):942-55.
  3. Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L.Multiple sclerosis: MHC associations and therapeutic implications. Expert Rev Mol Med (2005) 7(3):1-17.
  4. Venken K, Hellings N, Liblau R, Stinissen P. Disturbed regulatory T cell homeostasis in multiple sclerosis. Trends Mol Med (2010) 16(2):58-68.
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