Nachury:Research

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(Vesicular transport to the primary cilium: basic principles)
(Vesicular transport to the primary cilium: basic principles)
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== Vesicular transport to the primary cilium: basic principles ==
== Vesicular transport to the primary cilium: basic principles ==
[[image:Cilium_Anderson.jpg|thumb|200px|left]]
[[image:Cilium_Anderson.jpg|thumb|200px|left]]
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The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona-fide'' organelle.
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The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona-fide'' compartment exposed to the extracellular milieu. Consequently, the cilium has been compared to a "cellular antenna".
== Regulated transport to the primary cilium ==
== Regulated transport to the primary cilium ==

Revision as of 00:26, 11 January 2008

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Research

Vesicular transport to the primary cilium: basic principles

The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a bona-fide compartment exposed to the extracellular milieu. Consequently, the cilium has been compared to a "cellular antenna".

Regulated transport to the primary cilium


Discovery of novel ciliary signaling pathways


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