Nachury:Research
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== Vesicular transport to the primary cilium: basic principles == | == Vesicular transport to the primary cilium: basic principles == | ||
[[image:Cilium_Anderson.jpg|thumb|200px|left]] | [[image:Cilium_Anderson.jpg|thumb|200px|left]] | ||
| - | The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona | + | The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona fide'' compartment exposed to the extracellular milieu. Consequently, the cilium has been compared to a "cellular antenna" that capture and transduces developmental signal to the inside of the cell. |
== Regulated transport to the primary cilium == | == Regulated transport to the primary cilium == | ||
Revision as of 00:28, 11 January 2008
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