Nelson:Projects: Difference between revisions

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(New page: == Bacteriophage T4 Recombination-dependent DNA Repair == '''Mre11/Rad50:''' '''UvsW Helicase:''' '''UvsX and UvsY:''' == Mammalian Mitochondrial DNA Replication == '''Replicative He...)
 
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== Bacteriophage T4 Recombination-dependent DNA Repair ==
== Bacteriophage T4 Recombination-dependent DNA Repair ==
T4 phage is able to perform all the functions required for the replication and maintenance of its genome.  Decades of research has proven T4 phage to be an excellent model system.  The molecular mechanisms of the core DNA replication proteins (e.g., polymerase, helicase, clamp protein) are well conserved from phage to humans.  It is expected that this conservation will extend to the DNA repair enzymes.<br> 


'''Mre11/Rad50:'''
'''Mre11/Rad50:'''

Revision as of 05:35, 21 October 2008

Bacteriophage T4 Recombination-dependent DNA Repair

T4 phage is able to perform all the functions required for the replication and maintenance of its genome. Decades of research has proven T4 phage to be an excellent model system. The molecular mechanisms of the core DNA replication proteins (e.g., polymerase, helicase, clamp protein) are well conserved from phage to humans. It is expected that this conservation will extend to the DNA repair enzymes.

Mre11/Rad50:

UvsW Helicase:

UvsX and UvsY:


Mammalian Mitochondrial DNA Replication

Replicative Helicase (twinkle):

Polymerase gamma A:

Polymerase gamma B:

Single-stranded DNA Binding Protein:

Topoisomerase:

RNA polymerase (primase):