Nonlinear Dynamics in Biological Systems: Difference between revisions

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in class covered: identify the bifurcations in the May cow problem, what is a bifurcation, critical parameter values, saddle node bifurcations, introduce bifurcation diagrams
in class covered: identify the bifurcations in the May cow problem, what is a bifurcation, critical parameter values, saddle node bifurcations, introduce bifurcation diagrams


'''Wed Aud 29th'''
'''Wed Aug 29th'''
in classe covered: transcritical bifurcations, pitchfork (super and subcritical)
in classe covered: transcritical bifurcations, pitchfork (super and subcritical)
'''Fri Aug 31st'''
tumor problem - 2 parameter, 1D system with multiple bifurcations.  creating stability diagrams


==Background Math to Brush Up On==
==Background Math to Brush Up On==

Revision as of 06:46, 30 August 2007

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General Announcements

Coures Outline and Syllabus

This course is an introduction to nonlinear dynamics with applications to biology targeted to junior/senior engineering students and 1st year graduate students in engineering and quantitative life sciences.

Syllabus

Course Outline

We will use Strogatz as our main text and supplement with outside biological examples.

Questions for Professor Rickus or TA Mike

Organize Team Groups and Topics

A chemistry graduate student is looking for more people interested in intracellullar calcium oscillations (i.e. calcium induced calcium release).  As of Friday after class, need 3-4 people.  Contact mcgreen@purdue.edu


neurological signals (3): Brandon Davis, Nicole Meehan, Omeed Paydar, Andrew Pierce

neuronal firing:(4) Timu Gallien, Julie Morby, Michelle Scheidt, Mark Wilson

cadiac modeling(5), Matt Croxall, Meghan Floyd, Erica Halsey, Shari Hatfield, Rohit Shah

bacterial rock paper scissors(3):Team Grad Minority. Alex DiMauro, Trisha Eustaquio, and Nick Snead

circadian rhythms(4): Jeremy Schaeffer, Arun Mohan , Drew Lengerich, Shaunak A Kothari

cell differentiation(4): Sarah Noble, Paul Critser, Prasad Siddavatam, Jiji Chen

team name: The Bowman Group, members: Chris Fancher, Todd Shuba, and Ben Zajeski and area of interest: Fermentation

Hospital sustainability(4): Steve Higbee, Halle Burton, Tyler MacBroom, Steven Lee

Team Name: The Metabolites, Members: Brooke Beier, Eric Brandner, Elizabeth Casey, Eric HodgmanAreas of interest: Metabolism and neuron cells, Potential Project Area: Metabolic flux of neuron cells during firing

Lecture Notes and Topics

Monday August 20 Lecture 1 powerpoint

Wed Aug 22 in class covered: projects, email list, class wiki, state space, existence and uniqueness, trajectory, dimensionality, possible behavior of 1,2,3 D systems, coverting higher order and time dependent equations to state space, intro to stability, intro to vector fields, autocatalysis example Chapter 1 notes

Fri Aug 24th in class covered: projects, review stability of fixed points, look at linear examples, linear stability analysis, classic May problem: cows in the field

Mon Aug 27th in class covered: identify the bifurcations in the May cow problem, what is a bifurcation, critical parameter values, saddle node bifurcations, introduce bifurcation diagrams

Wed Aug 29th in classe covered: transcritical bifurcations, pitchfork (super and subcritical)

Fri Aug 31st tumor problem - 2 parameter, 1D system with multiple bifurcations. creating stability diagrams

Background Math to Brush Up On

these following things should be 2nd nature to you. if they are hazing from the summer fun, it would be best to brush up now.

  1. sketching of common functions: exponentials [math]\displaystyle{ exp(ax) }[/math], [math]\displaystyle{ sin(x) }[/math], [math]\displaystyle{ cos(x) }[/math], [math]\displaystyle{ x / x+1 }[/math], more generally [math]\displaystyle{ ax^n /(x^n+b) }[/math], polynomials
  2. taking derivatives of common functions
  3. solving simple linear ODEs [math]\displaystyle{ dx/dt = kx }[/math]
  4. finding eigenvalues and eigenvectors
  5. Taylor series expansion
  6. solving polynomials
  7. complex numbers