OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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==Objectives of the OHSU Cancer Biology Journal Club==
==Objectives of the OHSU Cancer Biology Journal Club==


Cross-departmental workshop composed of students, postdocs, and faculty with shared interest in basic principles and emerging discoveries in Cancer Biology. The goals of the meetings and this wiki:
Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles,  emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:
* Establish a challenging and interactive cross-departmental focus group that will advance understanding of our individual projects and encourage collaborations.
* Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
*Provide students and postdocs with training and interactions with faculty interested in Cancer Biology and emerging therapeutics
*Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics


==OCI CJC Activities==
==KCI CJC Information==
Want to join us? All are invited!
Want to join us? All are invited!
:To get on the listserve:  
*To get on the listserve:  
:Email: majordomoATohsu.edu  (must be sent as a plain text email)
:go to the following web site:
:subject: subscribe oncobio
:http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
:text box: subscribe oncobio
:follow instructions for subscribing
 
*To send out your paper
:Send an e-mail to 'oncobioATohsu.edu' with your paper attached
*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by OCI
:Lunch provided by KCI
*Organizer contact information: searsrATohsu.edu, lopezcATohsu.edu
*Organizer contact information:  
*
: Mushui Dai-daim@ohsu.edu
*
: Charlie Lopez- lopezc@ohsu.edu


==Member Labs and Affiliations==
==Member Labs and Affiliations==
Line 49: Line 50:


|--
|--
|9/30/2010
|10/1/2013
|Rosie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/7/2010
|10/8/2013
|Amy Farrell
|Mahnaz Janghorban
|Ubiquitylation of the amino terminus of Myc by SCF<sup>β-TrCp</sup> antagonizes SCF<sup>Fbw7</sup>-mediated turnover
|
|[http://openwetware.org/images/c/c9/Farrell_cancer_JC_article.pdf]
|
|--
|--
|10/14/2010
|10/15/2013
|David Qian
|Xiaoxin Sun
|Signaling Kinase AMPK Activates
|
Stress-Promoted Transcription via
Histone H2B Phosphorylation
|[http://openwetware.org/images/8/83/1201.pdf]
|--
|--
|10/21/2010
|10/22/2013
|Anupriya Agarwal
|Yulong Su
| Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
|
| [http://openwetware.org/wiki/Image:Nature09454-1.pdf] [http://openwetware.org/wiki/Image:Nature08902.pdf] [http://openwetware.org/wiki/Image:Nature08902-s1.pdf]
|
|--
|--
|10/28/2010
|10/29/2013
|Deanne Tibbitts
| Stacey Lin
| Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
|
|[http://openwetware.org/images/a/a9/Zhang2010CancerCell.pdf] [http://openwetware.org/images/8/89/Zhang2010Suppl.pdf]
|--  
|--  
|11/4/2010
|11/5/2013
|Mushui Dai
|Derek Zachaman
|An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction
|
|[http://openwetware.org/images/f/f7/2010-Zhang-L11-CancerCell.pdf]
|
|--
|--
|11/11/2010
|11/12/2013
|Katy Van Hook
|Marilynn Chow
|Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity
|
|[http://openwetware.org/wiki/Image:Saccheri_F_%282010%29.pdf Saccheri F (2010)] [http://openwetware.org/wiki/Image:Saccheri_F_%282010%29_supp.pdf Supp data]
|
|--
|--
|11/18/2010
|11/19/2013
|Aaron Wortham
|Michael Verga
|Cytohesins Are Cytoplasmic ErbB Receptor Activators
|
|[http://openwetware.org/images/5/5d/Cytohesins_Are_Cytoplasmic_ErbB_Receptor_Activators.pdf Article with Supp Data]
|  
|--
|11/26/2013
|Kevin Watanabe-Smith
|
|
|--
|12/3/2013
|Tim Butler
|
|
|--
|12/10/2013
|Brittany Allen-Petersen
|
|
|--
|--
|11/25/2010
|12/17/2013
|xxxxxxxxxx
|Canceled
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|12/2/2010
|12/24/2013
|Xiaoli Zhang
|Canceled
|A Stapled p53 Helix overcomes HDMX-mediated suppression of p53
|
|[http://openwetware.org/images/2/2b/A_stapled_p53_Helix_overcomes_HDMX-mediated_suppression_of_p53.pdf]
|
|--
|--
|12/9/2010
|12/31/2013
|CANCELLED
|Canceled
|
|
|
|
|--
|--
|12/16/2010
|1/7/2014
|Beibei Dong
|Aaron Wortham
|Copper Transporter and Cisplatin
|The Naked Mole Rat and Cancer: What we can learn from (one of) nature's ugliest creatures
|[http://openwetware.org/images/3/38/Copper_transporter_and_cisplatin.pdf]
|
|--
|--
|1/6/2011
|1/14/2014
|Alain Silk
|Chelsea Jenkins
|Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization
|
|[http://openwetware.org/images/c/c1/Tvorogov_CancerCell_2101.pdf]
|  
|--
|--
|1/13/2011
|1/21/2014
|Xiao-Xin Sun
|Juan Liang
|Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer; ( Schramek D et al,  Nature. 2010 Nov 4;468(7320):98-102)
|
|
|
|--
|--
|1/20/2011
|1/28/2014
|Eric Stoffregen
|Charlie Gast
|Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation
|
|[http://openwetware.org/images/5/5f/Wilson_et_al_2010_Cancer_Cell_Epigenetic_Antagonism_PCG_and_SWI_SNF.pdf Wilson et al 2010]
|  
|--
|--
|1/27/2011
|2/4/2014
|Mahnaz Janghorban
|Ellie Juarez
|B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
|
|[http://openwetware.org/images/3/36/B55%CE%B2-associated_PP2A_complex_controls_PDK1-directed_myc_signaling_and_modulates_rapamycin_sensitivity_in_colorectal_cancer.pdf Tan et al 2010]
|
|--
|--
|2/3/2011
|2/11/2014
|Katannya Kapeli
|Tiffany DeVine
|The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma
|
|[http://openwetware.org/images/b/b1/MiR-17-92_Mol_Cell_2010.pdf miR-17-92]
|
    [http://openwetware.org/images/5/56/Supplemental_Data.pdf supplemental data]
|--
|--
|2/10/2011
|2/18/2014
|Jared Fischer
|Tyler Risom
|Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
|
|[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-514HKDK-K&_user=1072900&_coverDate=10%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000048262&_version=1&_urlVersion=0&_userid=1072900&md5=af1b7898b94d963f443267b44480597f&searchtype=a]
|
|--
|--
|2/17/2011
|2/25/2014
|Jason Link
|Amy Farrell
|Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
|
|[http://www.sciencedirect.com.liboff.ohsu.edu/science?_ob=MImg&_imagekey=B6WWK-5112P5B-4-2&_cdi=7133&_user=1072900&_pii=S1535610810003065&_coverDate=09%2F14%2F2010&_sk=%23TOC%237133%232010%23999819996%232374734%23FLA%23display%23Volume_18,_Issue_3,_Pages_199-294_%2814_September_2010%29%23tagged%23Volume%23first%3D18%23Issue%23first%3D3%23date%23%2814_September_2010%29%23&view=c&_gw=y&wchp=dGLzVlb-zSkzk&md5=e10f32a04ce693193293386e97d39fa3&ie=/sdarticle.pdf]
|
|--
|--
|2/24/2011
|3/4/2014
|Rosie Sears
| Asia Mitchell
|The blind spot of p53 <br> Stage-specific sensitivity to p53 restoration during lung cancer progression <br> Selective activation of p53-mediated tumour suppression in high-grade tumours
|
|[http://openwetware.org/wiki/Image:Nature468519a.pdf blind spot]<br>
|
[http://openwetware.org/wiki/Image:Nature09535.pdf stage-specific] <br>
[http://openwetware.org/wiki/Image:Nature09526.pdf selective activation]
|--
|--
|3/3/2011
|3/11/2014
|Amy Skinner
|Spencer Watson
|Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WWK-525RKWB-7-1&_cdi=7133&_user=1072900&_pii=S1535610811000420&_origin=gateway&_coverDate=02%2F15%2F2011&_sk=%23TOC%237133%232011%23999809997%232907735%23FLA%23display%23Volume_19,_Issue_2,_Pages_157-294_(15_February_2011)%23tagged%23Volume%23first%3D19%23Issue%23first%3D2%23date%23(15_February_2011)%23&view=c&_gw=y&wchp=dGLbVzW-zSkWb&md5=04be5f8d0326da5305d046357fbf4452&ie=/sdarticle.pdf Quante et al 2011]
|
|--
|--
|3/10/2011
|3/18/2014
|Tiffany DeVine
|Zip Feng
|Activation of mTORC2 by Association with the Ribosome
|
|[http://openwetware.org/wiki/Image:Zinzalla_2011_Activation_of_mTORC2_by_Association_with_the_Ribosome.pdf]
|
|--
|--
|3/17/2011
|3/25/2014
|Aaron Jacobs
|Jason Link
|Identification of Aneuploidy-Selective Antiproliferation Compounds
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-524WT51-1-1&_cdi=7051&_user=1072900&_pii=S0092867411000560&_origin=gateway&_coverDate=02%2F18%2F2011&_sk=998559995&view=c&wchp=dGLbVzW-zSkWb&md5=e1d1eb10d4ae1c8bdff8acf5df6ff3ab&ie=/sdarticle.pdf Tang et al 2011]
|
|--
|--
|3/31/2011
|4/1/2014
|Harini Sampath
|Canceled
|Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
|
|[http://openwetware.org/images/6/64/Park_et_al.pdf Park et al]
|
|--
|--
|4/7/2011
|4/8/2014
|Yun Xin Lim
|Xiaoming Ouyang
|Sensitivity to Atitubulin Chemotherapeutics is Regulated by MC:1 and FBW7
|
|[http://openwetware.org/images/d/d4/Sensitivity_to_antitubulin_chemotherapeutics_is_regulated_by_MCL1_and_FBW7.pdf]
|
|--
|--
|4/14/2011
|4/15/2014
|Gregory Gores, M.D.
|Lilli Welch
Division of Gastroenterology and Hepatology Mayo Clinic, Rochester, MN
|
|TRAIL triggers the lysosomal pathway of apoptosis
|
|Vollum M1441
|--
|--
|4/21/2011
|4/22/2014
|Liangqi Xie
|Shannon Liudahl
|Rapid Scalable RNA1 in Mice
|
|[http://openwetware.org/images/3/32/RapidScalableRNAi_in_mice_Cell_2011.pdf Cell 2011]
|
|--
|--
|4/28/2011
|4/29/2013
|Kinrin Yamanaka
|Daniel Li
|DNA damage-mediated induction of chemoresistant niche
|
|[http://openwetware.org/images/b/b6/Article_JC.pdf]
|
|--
|--
|5/5/2011
|5/6/2014
|Kishore Challagundla
|Canceled---research week
|LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans
|
|[http://openwetware.org/images/c/cb/Journal_Club_May_5%2C_2011.pdf]
|--
|--
|5/12/2011
|5/13/2014
|David Edwards
|
|
|*****STUDENT RESEARCH FORUM*****
|
|
|--
|--
|5/19/2011
|5/20/2014
|Jeff Wu
|Jeffrey Wu
|Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
|
|[http://openwetware.org/images/0/09/Ren_et_al._pnas2011.pdf Article]<br>[http://openwetware.org/images/0/03/Nrf2_pnas.201014275SI.pdf supp data]
|
|--
|--
|5/26/2011
|5/27/2014
|Vince Bicocca
|Hyunju Ryu
|AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity
|
|[http://www.cell.com/cancer-cell/abstract/S1535-6108%2810%2900433-2?switch=standard Cancer Cell Abstract]
|
|--
|--
|6/2/2011
|6/3/2014
|Arun Krishnamoorthy
|
|
|
|
|
|--
|--
|6/9/2010
|6/10/2014
|
|
|
|Xiangshu Xiao
|
|
|}
|}
</div>
</div>

Revision as of 11:44, 22 April 2014

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
10/1/2013 Organization
10/8/2013 Mahnaz Janghorban
10/15/2013 Xiaoxin Sun
10/22/2013 Yulong Su
10/29/2013 Stacey Lin
11/5/2013 Derek Zachaman
11/12/2013 Marilynn Chow
11/19/2013 Michael Verga
11/26/2013 Kevin Watanabe-Smith
12/3/2013 Tim Butler
12/10/2013 Brittany Allen-Petersen
12/17/2013 Canceled
12/24/2013 Canceled
12/31/2013 Canceled
1/7/2014 Aaron Wortham The Naked Mole Rat and Cancer: What we can learn from (one of) nature's ugliest creatures
1/14/2014 Chelsea Jenkins
1/21/2014 Juan Liang
1/28/2014 Charlie Gast
2/4/2014 Ellie Juarez
2/11/2014 Tiffany DeVine
2/18/2014 Tyler Risom
2/25/2014 Amy Farrell
3/4/2014 Asia Mitchell
3/11/2014 Spencer Watson
3/18/2014 Zip Feng
3/25/2014 Jason Link
4/1/2014 Canceled
4/8/2014 Xiaoming Ouyang
4/15/2014 Lilli Welch
4/22/2014 Shannon Liudahl
4/29/2013 Daniel Li
5/6/2014 Canceled---research week
5/13/2014 David Edwards
5/20/2014 Jeffrey Wu
5/27/2014 Hyunju Ryu
6/3/2014
6/10/2014
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