OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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==Objectives of the OHSU Cancer Biology Journal Club==
==Objectives of the OHSU Cancer Biology Journal Club==


Cross-departmental workshop composed of students, postdocs, and faculty with shared interest in basic principles and emerging discoveries in Cancer Biology. The goals of the meetings and this wiki:
Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles,  emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:
* Establish a challenging and interactive cross-departmental focus group that will advance understanding of our individual projects and encourage collaborations.
* Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
*Provide students and postdocs with training and interactions with faculty interested in Cancer Biology and emerging therapeutics
*Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics


==OCI CJC Activities==
==KCI CJC Information==
Want to join us? All are invited!
Want to join us? All are invited!
:To get on the listserve:  
*To get on the listserve:  
:Email: majordomoATohsu.edu  (must be sent as a plain text email)
:go to the following web site:
:subject: subscribe oncobio
:http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
:text box: subscribe oncobio
:follow instructions for subscribing
 
*To send out your paper
:Send an e-mail to 'oncobioATohsu.edu' with your paper attached
*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by OCI
:Lunch provided by KCI
*Organizer contact information: searsrATohsu.edu, lopezcATohsu.edu
*Organizer contact information:  
*
: Mushui Dai-daim@ohsu.edu
*
: Charlie Lopez- lopezc@ohsu.edu
: David Qian-qianzh@ohsu.edu


==Member Labs and Affiliations==
==Member Labs and Affiliations==
Line 49: Line 51:


|--
|--
|9/30/2010
|09/30/2014
|Rosie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/7/2010
|10/7/2014
|Amy Farrell
|Tiffany DeVine
|Ubiquitylation of the amino terminus of Myc by SCF<sup>β-TrCp</sup> antagonizes SCF<sup>Fbw7</sup>-mediated turnover
|
|[http://openwetware.org/images/c/c9/Farrell_cancer_JC_article.pdf]
|
|--
|--
|10/14/2010
|10/14/2014
|David Qian
|Brittany Allen-Petersen
|Signaling Kinase AMPK Activates
|
Stress-Promoted Transcription via
Histone H2B Phosphorylation
|[http://openwetware.org/images/8/83/1201.pdf]
|--
|--
|10/21/2010
|10/21/2014
|Anupriya Agarwal
|Yulong Su
| Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
|
| [http://openwetware.org/wiki/Image:Nature09454-1.pdf] [http://openwetware.org/wiki/Image:Nature08902.pdf] [http://openwetware.org/wiki/Image:Nature08902-s1.pdf]
|
|--
|--
|10/28/2010
|10/28/2014
|Deanne Tibbitts
|Canceled
| Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
|
|[http://openwetware.org/images/a/a9/Zhang2010CancerCell.pdf] [http://openwetware.org/images/8/89/Zhang2010Suppl.pdf]
|--  
|--  
|11/4/2010
|11/4/2014
|Mushui Dai
|Ben Doron
|An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction
|
|[http://openwetware.org/images/f/f7/2010-Zhang-L11-CancerCell.pdf]
|
|--
|11/11/2014
|Ellen Langer
|
|
|--
|11/18/2014
|Canceled
|
|
|--
|11/25/2014
|Asia Mitchell
|
|
|--
|--
|11/11/2010
|12/02/2014
|Katy Van Hook
|Erica Goddard
|Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity
|
|[http://openwetware.org/wiki/Image:Saccheri_F_%282010%29.pdf Saccheri F (2010)] [http://openwetware.org/wiki/Image:Saccheri_F_%282010%29_supp.pdf Supp data]
|
|--
|--
|11/18/2010
|12/09/2014
|Aaron Wortham
|Aaron Wortham
|Cytohesins Are Cytoplasmic ErbB Receptor Activators
|
|[http://openwetware.org/images/5/5d/Cytohesins_Are_Cytoplasmic_ErbB_Receptor_Activators.pdf Article with Supp Data]
|
|--
|--
|11/25/2010
|12/16/2014
|xxxxxxxxxx
|Tim Butler
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|12/2/2010
|12/23/2014
|Xiaoli Zhang
|Canceled
|A Stapled p53 Helix overcomes HDMX-mediated suppression of p53
|
|[http://openwetware.org/images/2/2b/A_stapled_p53_Helix_overcomes_HDMX-mediated_suppression_of_p53.pdf]
|
|--
|--
|12/9/2010
|12/30/2014
|CANCELLED
|Canceled
|
|
|
|
|--
|--
|12/16/2010
|1/6/2015
|Beibei Dong
|Ellie Juaret
|Copper Transporter and Cisplatin
|
|[http://openwetware.org/images/3/38/Copper_transporter_and_cisplatin.pdf]
|
|--
|--
|1/6/2011
|1/13/2015
|Alain Silk
|Lilli Klug
|Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization
|
|[http://openwetware.org/images/c/c1/Tvorogov_CancerCell_2101.pdf]
|  
|--
|--
|1/13/2011
|1/20/2015
|Xiao-Xin Sun
|Shannon Lindahl
|Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer; ( Schramek D et al,  Nature. 2010 Nov 4;468(7320):98-102)
|
|
|
|--
|--
|1/20/2011
|1/27/2015
|Eric Stoffregen
|Marilynn Cho
|Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation
|
|[http://openwetware.org/images/5/5f/Wilson_et_al_2010_Cancer_Cell_Epigenetic_Antagonism_PCG_and_SWI_SNF.pdf Wilson et al 2010]
|  
|--
|--
|1/27/2011
|2/3/2015
|Mahnaz Janghorban
|Chelsea Jenkins
|B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
|
|[http://openwetware.org/images/3/36/B55%CE%B2-associated_PP2A_complex_controls_PDK1-directed_myc_signaling_and_modulates_rapamycin_sensitivity_in_colorectal_cancer.pdf Tan et al 2010]
|
|--
|--
|2/3/2011
|2/10/2015
|Katannya Kapeli
|Amber Bannon
|The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma
|
|[http://openwetware.org/images/b/b1/MiR-17-92_Mol_Cell_2010.pdf miR-17-92]
|
    [http://openwetware.org/images/5/56/Supplemental_Data.pdf supplemental data]
|--
|--
|2/10/2011
|2/17/2015
|Jared Fischer
|David Edwards
|Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
|
|[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-514HKDK-K&_user=1072900&_coverDate=10%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000048262&_version=1&_urlVersion=0&_userid=1072900&md5=af1b7898b94d963f443267b44480597f&searchtype=a]
|
|--
|--
|2/17/2011
|2/24/2015
|Jason Link
|Courtney Betts
|Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
|
|[http://www.sciencedirect.com.liboff.ohsu.edu/science?_ob=MImg&_imagekey=B6WWK-5112P5B-4-2&_cdi=7133&_user=1072900&_pii=S1535610810003065&_coverDate=09%2F14%2F2010&_sk=%23TOC%237133%232010%23999819996%232374734%23FLA%23display%23Volume_18,_Issue_3,_Pages_199-294_%2814_September_2010%29%23tagged%23Volume%23first%3D18%23Issue%23first%3D3%23date%23%2814_September_2010%29%23&view=c&_gw=y&wchp=dGLzVlb-zSkzk&md5=e10f32a04ce693193293386e97d39fa3&ie=/sdarticle.pdf]
|
|--
|--
|2/24/2011
|3/3/2015
|Rosie Sears
|Mahnaz Janghorban (Canceled)
|The blind spot of p53 <br> Stage-specific sensitivity to p53 restoration during lung cancer progression <br> Selective activation of p53-mediated tumour suppression in high-grade tumours
|
|[http://openwetware.org/wiki/Image:Nature468519a.pdf blind spot]<br>
|
[http://openwetware.org/wiki/Image:Nature09535.pdf stage-specific] <br>
[http://openwetware.org/wiki/Image:Nature09526.pdf selective activation]
|--
|--
|3/3/2011
|3/10/2015
|Amy Skinner
|Kevin Watanabe-Smith
|Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WWK-525RKWB-7-1&_cdi=7133&_user=1072900&_pii=S1535610811000420&_origin=gateway&_coverDate=02%2F15%2F2011&_sk=%23TOC%237133%232011%23999809997%232907735%23FLA%23display%23Volume_19,_Issue_2,_Pages_157-294_(15_February_2011)%23tagged%23Volume%23first%3D19%23Issue%23first%3D2%23date%23(15_February_2011)%23&view=c&_gw=y&wchp=dGLbVzW-zSkWb&md5=04be5f8d0326da5305d046357fbf4452&ie=/sdarticle.pdf Quante et al 2011]
|
|--
|--
|3/10/2011
|3/17/2015
|Tiffany DeVine
|Stacy Lin
|Activation of mTORC2 by Association with the Ribosome
|
|[http://openwetware.org/wiki/Image:Zinzalla_2011_Activation_of_mTORC2_by_Association_with_the_Ribosome.pdf]
|
|--
|--
|3/17/2011
|3/24/2015
|Aaron Jacobs
|Canceled, spring break
|Identification of Aneuploidy-Selective Antiproliferation Compounds
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-524WT51-1-1&_cdi=7051&_user=1072900&_pii=S0092867411000560&_origin=gateway&_coverDate=02%2F18%2F2011&_sk=998559995&view=c&wchp=dGLbVzW-zSkWb&md5=e1d1eb10d4ae1c8bdff8acf5df6ff3ab&ie=/sdarticle.pdf Tang et al 2011]
|
|--
|--
|3/31/2011
|3/31/2015
|Harini Sampath
|Tyler Rison
|Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
|
|[http://openwetware.org/images/6/64/Park_et_al.pdf Park et al]
|
|--
|--
|4/7/2011
|4/7/2015
|Yun Xin Lim
|Qiuchen Guo
|Sensitivity to Atitubulin Chemotherapeutics is Regulated by MC:1 and FBW7
|
|[http://openwetware.org/images/d/d4/Sensitivity_to_antitubulin_chemotherapeutics_is_regulated_by_MCL1_and_FBW7.pdf]
|
|--
|--
|4/14/2011
|4/14/2015
|Gregory Gores, M.D.
|Xiaoming Ouyang
Division of Gastroenterology and Hepatology Mayo Clinic, Rochester, MN
|
|TRAIL triggers the lysosomal pathway of apoptosis
|
|Vollum M1441
|--
|--
|4/21/2011
|4/21/2015
|Liangqi Xie
|Michael Veraz
|Rapid Scalable RNA1 in Mice
|
|[http://openwetware.org/images/3/32/RapidScalableRNAi_in_mice_Cell_2011.pdf Cell 2011]
|
|--
|--
|4/28/2011
|4/28/2015
|Kinrin Yamanaka
|Erin Wiedmeier
|DNA damage-mediated induction of chemoresistant niche
|
|[http://openwetware.org/images/b/b6/Article_JC.pdf]
|
|--
|--
|5/5/2011
|5/5/2015
|Kishore Challagundla
|Canceled---research week
|LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans
|
|[http://openwetware.org/images/c/cb/Journal_Club_May_5%2C_2011.pdf]
|--
|--
|5/12/2011
|5/12/2015
|Spencer Watson
|
|
|*****STUDENT RESEARCH FORUM*****
|
|
|--
|--
|5/19/2011
|5/19/2015
|Jeff Wu
|Hyunju Ryu
|Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
|
|[http://openwetware.org/images/0/09/Ren_et_al._pnas2011.pdf Article]<br>[http://openwetware.org/images/0/03/Nrf2_pnas.201014275SI.pdf supp data]
|
|--
|--
|5/26/2011
|5/26/2015
|Vince Bicocca
|
|AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity
|
|[http://www.cell.com/cancer-cell/abstract/S1535-6108%2810%2900433-2?switch=standard Cancer Cell Abstract]
|
|--
|--
|6/2/2011
|6/2/2015
|Arun Krishnamoorthy
|
|
|
|
|
|--
|--
|6/9/2010
|6/09/2015
|Christopher Boniface
|
|
|Xiangshu Xiao
|
|
|}
|}
</div>
</div>

Revision as of 11:52, 9 March 2015

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu
David Qian-qianzh@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
09/30/2014 Organization
10/7/2014 Tiffany DeVine
10/14/2014 Brittany Allen-Petersen
10/21/2014 Yulong Su
10/28/2014 Canceled
11/4/2014 Ben Doron
11/11/2014 Ellen Langer
11/18/2014 Canceled
11/25/2014 Asia Mitchell
12/02/2014 Erica Goddard
12/09/2014 Aaron Wortham
12/16/2014 Tim Butler
12/23/2014 Canceled
12/30/2014 Canceled
1/6/2015 Ellie Juaret
1/13/2015 Lilli Klug
1/20/2015 Shannon Lindahl
1/27/2015 Marilynn Cho
2/3/2015 Chelsea Jenkins
2/10/2015 Amber Bannon
2/17/2015 David Edwards
2/24/2015 Courtney Betts
3/3/2015 Mahnaz Janghorban (Canceled)
3/10/2015 Kevin Watanabe-Smith
3/17/2015 Stacy Lin
3/24/2015 Canceled, spring break
3/31/2015 Tyler Rison
4/7/2015 Qiuchen Guo
4/14/2015 Xiaoming Ouyang
4/21/2015 Michael Veraz
4/28/2015 Erin Wiedmeier
5/5/2015 Canceled---research week
5/12/2015 Spencer Watson
5/19/2015 Hyunju Ryu
5/26/2015
6/2/2015
6/09/2015 Christopher Boniface
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