OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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==Objectives of the OHSU Cancer Biology Journal Club==
==Objectives of the OHSU Cancer Biology Journal Club==


Cross-departmental workshop composed of students, postdocs, and faculty with shared interest in basic principles and emerging discoveries in Cancer Biology. The goals of the meetings and this wiki:
Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles,  emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:
* Establish a challenging and interactive cross-departmental focus group that will advance understanding of our individual projects and encourage collaborations.
* Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
*Provide students and postdocs with training and interactions with faculty interested in Cancer Biology and emerging therapeutics
*Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics


==OCI CJC Activities==
==KCI CJC Information==
Want to join us? All are invited!
Want to join us? All are invited!
:To get on the listserve:  
*To get on the listserve:  
:Email: majordomoATohsu.edu  (must be sent as a plain text email)
:go to the following web site:
:subject: subscribe oncobio
:http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
:text box: subscribe oncobio
:follow instructions for subscribing
 
*To send out your paper
:Send an e-mail to 'oncobioATohsu.edu' with your paper attached
*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by OCI
:Lunch provided by KCI
*Organizer contact information: searsrATohsu.edu, lopezcATohsu.edu
*Organizer contact information:  
*
: Mushui Dai-daim@ohsu.edu
*
: Charlie Lopez- lopezc@ohsu.edu
: David Qian-qianzh@ohsu.edu


==Member Labs and Affiliations==
==Member Labs and Affiliations==
Line 49: Line 51:


|--
|--
|9/30/2010
|09/29/2015
|Rosie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/7/2010
|10/6/2015
|Amy Farrell
|Marilynn Chow
|Ubiquitylation of the amino terminus of Myc by SCF<sup>β-TrCp</sup> antagonizes SCF<sup>Fbw7</sup>-mediated turnover
|
|[http://openwetware.org/images/c/c9/Farrell_cancer_JC_article.pdf]
|
|--
|--
|10/14/2010
|10/13/2015
|David Qian
|Kevin Watanabe-Smith
|Signaling Kinase AMPK Activates
|
Stress-Promoted Transcription via
|
Histone H2B Phosphorylation
|[http://openwetware.org/images/8/83/1201.pdf]
|--
|--
|10/21/2010
|10/20/2015
|Anupriya Agarwal
|David Edwards
| Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
|
| [http://openwetware.org/wiki/Image:Nature09454-1.pdf] [http://openwetware.org/wiki/Image:Nature08902.pdf] [http://openwetware.org/wiki/Image:Nature08902-s1.pdf]
|
|--
|--
|10/28/2010
|10/27/2015
|Deanne Tibbitts
|Xiaoxin Sun
| Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
|
|[http://openwetware.org/images/a/a9/Zhang2010CancerCell.pdf] [http://openwetware.org/images/8/89/Zhang2010Suppl.pdf]
|
|--  
|--  
|11/4/2010
|11/3/2015
|Mushui Dai
|Ben Doron
|An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction
|
|[http://openwetware.org/images/f/f7/2010-Zhang-L11-CancerCell.pdf]
|
|--
|11/10/2015
|Erica Goddard
|
|
|--
|--
|11/11/2010
|11/17/2015
|Katy Van Hook
|Lilli Klug
|Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity
|
|[http://openwetware.org/wiki/Image:Saccheri_F_%282010%29.pdf Saccheri F (2010)] [http://openwetware.org/wiki/Image:Saccheri_F_%282010%29_supp.pdf Supp data]
|  
|--
|--
|11/18/2010
|11/24/2015
|Aaron Wortham
|Ryan Lane
|Cytohesins Are Cytoplasmic ErbB Receptor Activators
|
|[http://openwetware.org/images/5/5d/Cytohesins_Are_Cytoplasmic_ErbB_Receptor_Activators.pdf Article with Supp Data]
|
|--
|--
|11/25/2010
|12/01/2015
|xxxxxxxxxx
|Chelsea Jenkins
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|12/2/2010
|12/08/2015
|Xiaoli Zhang
|Xiaoming Ouyang
|A Stapled p53 Helix overcomes HDMX-mediated suppression of p53
|
|[http://openwetware.org/images/2/2b/A_stapled_p53_Helix_overcomes_HDMX-mediated_suppression_of_p53.pdf]
|
|--
|12/15/2015
|Shannon Lindahl
|
|
|--
|--
|12/9/2010
|12/22/2015
|CANCELLED
|NO JC
|
|
|
|
|--
|--
|12/16/2010
|12/29/2015
|Beibei Dong
|NO JC
|Copper Transporter and Cisplatin
|
|[http://openwetware.org/images/3/38/Copper_transporter_and_cisplatin.pdf]
|
|--
|--
|1/6/2011
|1/5/2016
|Alain Silk
|Baotong Xie
|Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization
|
|[http://openwetware.org/images/c/c1/Tvorogov_CancerCell_2101.pdf]
|
|--
|--
|1/13/2011
|1/12/2016
|Xiao-Xin Sun
|Kevin Watanabe-Smith
|Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer; ( Schramek D et al,  Nature. 2010 Nov 4;468(7320):98-102)
|
|
|
|--
|--
|1/20/2011
|1/19/2016
|Eric Stoffregen
|David Edwards
|Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation
|
|[http://openwetware.org/images/5/5f/Wilson_et_al_2010_Cancer_Cell_Epigenetic_Antagonism_PCG_and_SWI_SNF.pdf Wilson et al 2010]
|
|--
|--
|1/27/2011
|1/26/2016
|Mahnaz Janghorban
|Erica Goddard
|B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
|
|[http://openwetware.org/images/3/36/B55%CE%B2-associated_PP2A_complex_controls_PDK1-directed_myc_signaling_and_modulates_rapamycin_sensitivity_in_colorectal_cancer.pdf Tan et al 2010]
|  
|--
|--
|2/3/2011
|2/2/2016
|Katannya Kapeli
|Lilli Klug
|The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma
|
|[http://openwetware.org/images/b/b1/MiR-17-92_Mol_Cell_2010.pdf miR-17-92]
|
    [http://openwetware.org/images/5/56/Supplemental_Data.pdf supplemental data]
|--
|--
|2/10/2011
|2/09/2016
|Jared Fischer
|Marilynn Chow
|Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
|
|[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-514HKDK-K&_user=1072900&_coverDate=10%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000048262&_version=1&_urlVersion=0&_userid=1072900&md5=af1b7898b94d963f443267b44480597f&searchtype=a]
|
|--
|--
|2/17/2011
|2/16/2016
|Jason Link
|Qiuchen Guo
|Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
|
|[http://www.sciencedirect.com.liboff.ohsu.edu/science?_ob=MImg&_imagekey=B6WWK-5112P5B-4-2&_cdi=7133&_user=1072900&_pii=S1535610810003065&_coverDate=09%2F14%2F2010&_sk=%23TOC%237133%232010%23999819996%232374734%23FLA%23display%23Volume_18,_Issue_3,_Pages_199-294_%2814_September_2010%29%23tagged%23Volume%23first%3D18%23Issue%23first%3D3%23date%23%2814_September_2010%29%23&view=c&_gw=y&wchp=dGLzVlb-zSkzk&md5=e10f32a04ce693193293386e97d39fa3&ie=/sdarticle.pdf]
|
|--
|--
|2/24/2011
|2/23/2016
|Rosie Sears
|Chelsea Jenkins
|The blind spot of p53 <br> Stage-specific sensitivity to p53 restoration during lung cancer progression <br> Selective activation of p53-mediated tumour suppression in high-grade tumours
|
|[http://openwetware.org/wiki/Image:Nature468519a.pdf blind spot]<br>
|
[http://openwetware.org/wiki/Image:Nature09535.pdf stage-specific] <br>
[http://openwetware.org/wiki/Image:Nature09526.pdf selective activation]
|--
|--
|3/3/2011
|3/1/2016
|Amy Skinner
|Xiaoming Ouyang
|Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WWK-525RKWB-7-1&_cdi=7133&_user=1072900&_pii=S1535610811000420&_origin=gateway&_coverDate=02%2F15%2F2011&_sk=%23TOC%237133%232011%23999809997%232907735%23FLA%23display%23Volume_19,_Issue_2,_Pages_157-294_(15_February_2011)%23tagged%23Volume%23first%3D19%23Issue%23first%3D2%23date%23(15_February_2011)%23&view=c&_gw=y&wchp=dGLbVzW-zSkWb&md5=04be5f8d0326da5305d046357fbf4452&ie=/sdarticle.pdf Quante et al 2011]
|
|--
|--
|3/10/2011
|3/08/2016
|Tiffany DeVine
|Timothy Carey
|Activation of mTORC2 by Association with the Ribosome
|
|[http://openwetware.org/wiki/Image:Zinzalla_2011_Activation_of_mTORC2_by_Association_with_the_Ribosome.pdf]
|
|--
|--
|3/17/2011
|3/15/2016
|Aaron Jacobs
|Tyler Risom
|Identification of Aneuploidy-Selective Antiproliferation Compounds
|
|[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-524WT51-1-1&_cdi=7051&_user=1072900&_pii=S0092867411000560&_origin=gateway&_coverDate=02%2F18%2F2011&_sk=998559995&view=c&wchp=dGLbVzW-zSkWb&md5=e1d1eb10d4ae1c8bdff8acf5df6ff3ab&ie=/sdarticle.pdf Tang et al 2011]
|
|--
|--
|3/31/2011
|3/22/2016
|Harini Sampath
|Canceled, spring break
|Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
|
|[http://openwetware.org/images/6/64/Park_et_al.pdf Park et al]
|
|--
|--
|4/7/2011
|3/29/2016
|Yun Xin Lim
|Krishna Chauhan
|
|
|
|
|--
|--
|4/14/2011
|4/5/2016
|Liangqi Xie
|Ben Doron
|
|
|
|
|--
|--
|4/21/2011
|4/12/2016
|Ping Wang
|Yulong Su
|
|
|
|
|--
|--
|4/28/2011
|4/19/2016
|Kinrin Yamanaka
|Shannon Lindahl
|
|
|
|
|--
|--
|5/5/2011
|4/26/2016
|Kishore Challagundla
|Yingxiao Chen
|
|
|
|--
|5/3/2016
|Canceled---research week
|
|
|--
|--
|5/12/2011
|5/10/2016
|*****STUDENT RESEARCH FORUM*****
|Qiuchen Guo
|
|
|
|
|--
|--
|5/19/2011
|5/17/2016
|Jeff Wu
|Yulong Su
|
|
|
|
|--
|--
|5/26/2011
|5/24/2016
|Vince Bicocca
|Young Me Yoon
|
|
|
|
|--
|--
|6/2/2011
|5/31/2016
|Arun Krishnamoorthy
|
|
|
|
|
|--
|--
|6/9/2010
|6/07/2016
|
|
|Xiangshu Xiao
|
|
|}
|}
</div>
</div>

Revision as of 11:39, 13 January 2016

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu
David Qian-qianzh@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
09/29/2015 Organization
10/6/2015 Marilynn Chow
10/13/2015 Kevin Watanabe-Smith
10/20/2015 David Edwards
10/27/2015 Xiaoxin Sun
11/3/2015 Ben Doron
11/10/2015 Erica Goddard
11/17/2015 Lilli Klug
11/24/2015 Ryan Lane
12/01/2015 Chelsea Jenkins
12/08/2015 Xiaoming Ouyang
12/15/2015 Shannon Lindahl
12/22/2015 NO JC
12/29/2015 NO JC
1/5/2016 Baotong Xie
1/12/2016 Kevin Watanabe-Smith
1/19/2016 David Edwards
1/26/2016 Erica Goddard
2/2/2016 Lilli Klug
2/09/2016 Marilynn Chow
2/16/2016 Qiuchen Guo
2/23/2016 Chelsea Jenkins
3/1/2016 Xiaoming Ouyang
3/08/2016 Timothy Carey
3/15/2016 Tyler Risom
3/22/2016 Canceled, spring break
3/29/2016 Krishna Chauhan
4/5/2016 Ben Doron
4/12/2016 Yulong Su
4/19/2016 Shannon Lindahl
4/26/2016 Yingxiao Chen
5/3/2016 Canceled---research week
5/10/2016 Qiuchen Guo
5/17/2016 Yulong Su
5/24/2016 Young Me Yoon
5/31/2016
6/07/2016
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