OSDDMalaria - Revision history

Matthew Todd: /* Current Projects */

Matthew Todd — Wed, 08 May 2013 07:12:47 GMT

Current Projects

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	3) If you have no access to the lab, there are a number of important clerical things needed, for example:		3) If you have no access to the lab, there are a number of important clerical things needed, for example:

-	* Some of the recordings from ~~our~~ 2012 conference need to be uploaded to YouTube and have summaries written:	+	* Some of the recordings from the [http://openwetware.org/wiki/OSDDMalaria:OSDD_Malaria_Meeting_Sydney_2012 2012 OSDD Malaria conference] need to be uploaded to YouTube and have summaries written:
	[https://www.youtube.com/watch?v=3eP8OTFYjKA This recording] of Session 2 Part 2 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)<br>		[https://www.youtube.com/watch?v=3eP8OTFYjKA This recording] of Session 2 Part 2 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)<br>
	[https://www.youtube.com/watch?v=URoDLUvEUL0 This recording] of Session 2 Part 3 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)		[https://www.youtube.com/watch?v=URoDLUvEUL0 This recording] of Session 2 Part 3 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)

Matthew Todd: /* Current Projects */ added video annotation needs

Matthew Todd — Wed, 08 May 2013 07:02:16 GMT

Current Projects: added video annotation needs

←Older revision		Revision as of 07:02, 8 May 2013
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	3) If you have no access to the lab, there are a number of important clerical things needed, for example:		3) If you have no access to the lab, there are a number of important clerical things needed, for example:

-	* Some of the recordings from our 2012 conference need to be uploaded to YouTube and have summaries written. ~~More coming on~~ this.	+	* Some of the recordings from our 2012 conference need to be uploaded to YouTube and have summaries written:
		+	[https://www.youtube.com/watch?v=3eP8OTFYjKA This recording] of Session 2 Part 2 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)<br>
		+	[https://www.youtube.com/watch?v=URoDLUvEUL0 This recording] of Session 2 Part 3 needs to be added as a daughter page to [http://www.thesynapticleap.org/node/390 this blog post], and a clear summary written of what was discussed along the lines of [http://www.thesynapticleap.org/node/406 this example] of a previous session. (To work out how to format correctly, please view the page source. Please insert time stamps for each section so that the recording can be easily navigated)
	* This wiki can be refined and improved by anyone. More...		* This wiki can be refined and improved by anyone. More...
	* There are various website project needs. More...		* There are various website project needs. More...

Matthew Todd: Trying to add non-lab things that can be done

Matthew Todd — Wed, 08 May 2013 06:47:39 GMT

Trying to add non-lab things that can be done

←Older revision		Revision as of 06:47, 8 May 2013
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	At the moment there is a lot of activity on [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|'''Series 2''']].		At the moment there is a lot of activity on [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|'''Series 2''']].

-	There are lots of things needed~~, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD~~:~~Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].~~	+	There are lots of things needed:

-	~~Currently there are three active~~ [[~~OSDDMalaria~~:~~Projects~~\|~~projects~~]] ~~on-going:~~	+	1) The main thing is '''experimental input''', particularly compounds synthesis. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. If you want to cut to the technical details, here is a [[short guide to using the Electronic Lab Notebook]].

-	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]]	+	2) If you are not a research scientist but have access to a lab (maybe you're an undergrad doing a lab), you could try to do some simple analog synthesis. More coming. Biological evaluation of compounds can be arranged for anything made which is pure.
-	* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]	+
-	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]	+

-	=== Current Participants ===	+	3) If you have no access to the lab, there are a number of important clerical things needed, for example:
		+
		+	* Some of the recordings from our 2012 conference need to be uploaded to YouTube and have summaries written. More coming on this.
		+	* This wiki can be refined and improved by anyone. More...
		+	* There are various website project needs. More...
		+
		+	There have been three main active experimental [[OSDDMalaria:Projects\|projects]]:
		+
		+	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]] - possibly being wound up/written up/
		+	* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]] - some work done, not currently active.
		+	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]] - main current emphasis.
		+
		+	=== Some Current Participants ===

	==== Medicinal Chemistry ====		==== Medicinal Chemistry ====

Matthew Todd: /* Current Projects */

Matthew Todd — Wed, 01 May 2013 06:11:39 GMT

Current Projects

←Older revision		Revision as of 06:11, 1 May 2013
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	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|'''The Story So Far''']].		A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|'''The Story So Far''']].
		+
		+	At the moment there is a lot of activity on [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|'''Series 2''']].

	There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].		There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].

Matthew Todd: /* Current Projects */

Matthew Todd — Thu, 25 Apr 2013 14:06:18 GMT

Current Projects

←Older revision		Revision as of 14:06, 25 April 2013
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	== Current Projects ==		== Current Projects ==

-	~~There are lots~~ of ~~things needed, but the main thing is experimental input. If you're a scientist with access~~ to ~~a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go~~ [[~~OSDD~~:~~Huh%3F~~\|~~here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook~~]].	+	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|'''The Story So Far''']].

-	~~A summary~~ of ~~our efforts~~ to ~~date can be found in~~ [[~~OSDDMalaria~~:~~GSK Arylpyrrole Series:Story so far~~\|~~The Story So Far~~]].	+	There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].

	Currently there are three active [[OSDDMalaria:Projects\|projects]] on-going:		Currently there are three active [[OSDDMalaria:Projects\|projects]] on-going:

Alice E Williamson: /* Current Projects */

Alice E Williamson — Thu, 01 Nov 2012 05:56:37 GMT

Current Projects

←Older revision		Revision as of 05:56, 1 November 2012
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	* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]		* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]
	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]		* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]
-

	=== Current Participants ===		=== Current Participants ===

Alice E Williamson: /* Current Projects */

Alice E Williamson — Thu, 01 Nov 2012 05:52:02 GMT

Current Projects

←Older revision		Revision as of 05:52, 1 November 2012
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	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|The Story So Far]].		A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|The Story So Far]].

-	Currently there are three active projects on-going:	+	Currently there are three active [[OSDDMalaria:Projects\|projects]] on-going:

	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]]		* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]]
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	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]		* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]

-	~~Project entries will be listed at [[OSDDMalaria:Projects\|link]] in above menu.~~

	=== Current Participants ===		=== Current Participants ===

Alice E Williamson: changed links

Alice E Williamson — Thu, 01 Nov 2012 05:49:20 GMT

changed links

←Older revision		Revision as of 05:49, 1 November 2012
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	There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].		There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].
		+
		+	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|The Story So Far]].

	Currently there are three active projects on-going:		Currently there are three active projects on-going:

-	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]] ~~- plus a [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|human-readable summary]] of the current project status.~~	+	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]]
	* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]		* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]
	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]		* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]

Alice E Williamson: /* Discussion */

Alice E Williamson — Thu, 01 Nov 2012 04:56:11 GMT

Discussion

←Older revision		Revision as of 04:56, 1 November 2012
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	Relevant papers are available in the [http://www.mendeley.com/groups/1846251/osddmalaria/ Mendeley group], to which anyone can add.		Relevant papers are available in the [http://www.mendeley.com/groups/1846251/osddmalaria/ Mendeley group], to which anyone can add.
		+
		+	==Licence==
		+
		+	The project's licence unless otherwise stated is [http://creativecommons.org/licenses/by/3.0/ CC-BY-3.0] meaning you can use whatever you want for whatever purpose, provided you cite the project.

Alice E Williamson: moved from story so far

Alice E Williamson — Thu, 01 Nov 2012 04:32:54 GMT

moved from story so far

←Older revision		Revision as of 04:32, 1 November 2012
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	A competition is possible in the future, i.e. with a cash prize. Progress towards a very promising lead compound series has been rapid, but there is a long road to a compound that looks sufficiently promising that it moves towards clinical trials. There's a lot of tweaking needed, and perhaps even the move to another series. It is not obvious what will happen. It is certain the project will need a lot more input than it has received to date. A prize may increase traffic and input. The competition would be teamless, however, awarded based on performance of individuals within a group where everything is shared. Not sharing data or ideas leads to disqualification. Such a competition is difficult to judge, difficult to award, and hence almost certainly worth doing. More about this is [http://intermolecular.wordpress.com/2011/11/13/open-science-funding-government-grants-and-cash-incentives/ here].		A competition is possible in the future, i.e. with a cash prize. Progress towards a very promising lead compound series has been rapid, but there is a long road to a compound that looks sufficiently promising that it moves towards clinical trials. There's a lot of tweaking needed, and perhaps even the move to another series. It is not obvious what will happen. It is certain the project will need a lot more input than it has received to date. A prize may increase traffic and input. The competition would be teamless, however, awarded based on performance of individuals within a group where everything is shared. Not sharing data or ideas leads to disqualification. Such a competition is difficult to judge, difficult to award, and hence almost certainly worth doing. More about this is [http://intermolecular.wordpress.com/2011/11/13/open-science-funding-government-grants-and-cash-incentives/ here].
		+
		+	==Ownership==
		+
		+	A final point - the project is open. Nobody owns it. Those people most active in the project lead it while they are active. If you wish to contribute, in any capacity, please do so. There is no need to "clear" anything with existing project members by email first. To date is has been very common for current participants to receive questions/suggestions from people by email, which is to be discouraged. In the development of Linux, the need for Linus Torvalds to approve everything caused a serious bottleneck, and the observation that "Linus doesn't scale". ''Nobody scales, but the team does''. So it's more efficient if all the project discussions are held publicly. Many people do not like this idea. In science the idea of "beta testing" something is alien. When data are released in science there is an expectation that the data are correct, and essentially finished. This project eschews this view. All data are released immediately, all discussions are public, anyone can participate.

	== Discussion ==		== Discussion ==

←Older revision		Revision as of 06:11, 1 May 2013
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	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|'''The Story So Far''']].		A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|'''The Story So Far''']].
		+
		+	At the moment there is a lot of activity on [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|'''Series 2''']].

	There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].		There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].

←Older revision		Revision as of 05:49, 1 November 2012
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	There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].		There are lots of things needed, but the main thing is experimental input. If you're a scientist with access to a lab, open source drug discovery needs you. If you want to know what open source drug discovery is, go [[OSDD:Huh%3F\|here]]. For anyone new to the project here is a [[short guide to using the Electronic Lab Notebook]].
		+
		+	A summary of our efforts to date can be found in [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|The Story So Far]].

	Currently there are three active projects on-going:		Currently there are three active projects on-going:

-	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]] ~~- plus a [[OSDDMalaria:GSK Arylpyrrole Series:Story so far\|human-readable summary]] of the current project status.~~	+	* [[OSDDMalaria:GSK_Arylpyrrole_Series\|GSK arylpyrrole series]]
	* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]		* [[OSDDMalaria:GSK_Triazolourea_Singleton\|GSK Triazolourea Singleton]]
	* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]		* [[OSDDMalaria:GSK_Amino-thienopyrimidine_Series\|GSK Amino-thienopyrimidine Series]]