OpenWetWare:Presentations/NCI-ICBP

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OpenWetWare

A wiki for capturing and sharing biological knowledge

Reshma P. Shetty and Jeremy Muhlich

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Problem

Much of the knowledge produced by biological research is passed down by oral tradition.

This makes it difficult for newcomers to enter the field.

Solution: OpenWetWare

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OpenWetWare's contributions

  1. Democratizing and disseminating content generation
  2. Digitization of biological knowledge, as it is generated

Courses on OpenWetWare

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Student contributions to OpenWetWare

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Model Construction and Documentation

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Models Are Poorly Communicated

Knowledge generated during model building is lost!

It is difficult to:

  • construct a new model
  • build on published models
  • evaluate published models
  • involve experimentalists

What About MIRIAM, SBML, etc?

  • MIRIAM - Minimum Information Requested in the Annotation of Biochemical Models
  • SBML - Systems Biology Markup Language

OK for publishing, but too complicated for discovery!

Can we design something more "agile" while utilizing and respecting the established standards?

YeastPheromoneModel.org

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YeastPheromoneModel.org

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OpenWetWare's success

  • 2,800 contributors
  • 100 labs
  • 1.5 million pageviews per month
  • 275,000 sessions per month


http://openwetware.org


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