Pan:Nathan Baird

My research is aimed at understanding the structural basis of RNA folding and stability. In the last decade, major advancements have been made in the field of RNA crystallography, paving the way for atomic-level understanding of what drives the folding of biologically relevant RNAs. We use a wide variety of biophysical and biochemical techniques to create models of RNA folding intermediates. Our most recent work has involved electron cryomicroscopy and single particle reconstruction to directly image the catalytic and specificity domains of RNase P RNA.