From the South (Airport)
Take I-75/I-85 North to Exit 250 10th Street towards Georgia Tech/Fourteenth Street. Merge onto Williams Street NW. At the light, turn left onto 10th Street NW and then left on Atlantic Dr NW. The MoSE building will be on the left.
From the North (I-75S)
Take Exit 252 for US-41/Northside Dr towards Atlanta. Turn right at Northside Dr NW/US-41. At 10th Street NW, turn left. Turn right on Atlantic Dr NW.
From the North (I-85S)
Take Exit 84 towards 17th St/14th St/10th St. Keep left at the fork, follow signs for 10th St. At the light, turn right onto 10th St NW and then left onto Atlantic Dr NW.