Pecinka lab

Centre of Plant Structural and Functional Genomics Institute of Experimental Botany of the Czech Academy of Sciences, v. v. i. Šlechtitelů 31 Olomouc, CZ-783 71 Czech Republic Contact

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Research The Pecinka lab is hosted by the Department of Plant Breeding and Genetics at the Max Planck Institute for Plant Breeding Research in Cologne, Germany. Our goal is to understand molecular and evolutionary mechanisms shaping plant genomes and epigenomes. We analyze how DNA sequence and chromatin changes are generated by endo- and exogenous factors and how these forces are balanced by the genome repair and epigenetic mechanisms. To this end we use mainly the model plant Arabidopsis thaliana and several other Brassicaceae and analyze them by forward and reverse genetics, molecular, biochemical, cytogenetic and bioinformatic methods. read more...

Lab Members Mariana Andrea Diaz Smoje Andreas Finke Chun Hsin Liu (Phoebe) Ales Pecinka Björn Pietzenuk Thomas Piofczyk Technitians Barbara Eilts Petra Pecinkova see complete list...

Recent Publications Liu C-H, Finke A, Diaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A. (2015): Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis. Plant Cell doi/10.1105/tpc.114.135467 PDF. Baranauskė S, Mickutė M, Plotnikova A, Finke A, Venclovas Č, Klimašauskas S, Vilkaitis G. (2015): Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins. Nucleic Acids Research 43:2802-2812 Full text Willing, Rawat et al. (2015): Genome expansion of Arabis alpina linked with retrotransposition and reduced symmetric DNA methylation. Nature Plants 1:1-7 Full text Piofczyk T, Jeena G, Pecinka A. (2015): Arabidopsis thaliana natural variation reveals connections between UV radiation stress and plant pathogen-like defense responses. Plant Physiology Biochemistry DOI: 10.1016/j.plaphy.2015.01.011 (2015) Full text see complete list... News 2015-06-15: Ahmed successfully defended his PhD work at University of Göttingen. Congratulations! 2015-06: Not only DNA demethylation - cytidine analog zebularine triggers DNA damage response in Arabidopsis. Read more in our recent Plant Cell paper PDF 2015-05: Andreas co-authored on the paper showing physical interaction between specific miRNA components. Congratulations! Full text 2015-02-10: "Arabis alpina" genome reveals peculiar pattern of DNA methylation. See more in the current Nature Plants paper by Schneeberger lab Full text