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<h3><font color=#2>Welcome!</font></h3>
<h3><font color=#2>Welcome!</font></h3>
[[Image:Foxp3-GFP1.jpg|thumb]]
[[Image:Ana.jpg|thumb]]
Our main interest is to better understand the cellular and molecular basis for generation and maintenance of regulatory T cells (Tregs) in the suppression of autoimmunities and/or allergies in mouse models. We have been using intravital microscopy as the starting point for the in vivo imaging of Tregs. The use of a multi-photon microscope, the development of new intravital surgical tecniques and tools, and use of animal models that develop autoimmune and allergic diseases, we are evaluating what and where the important cell-cell contacts for Tregs generation/function happen. We hope that a better comprehension of generation and function of these Tregs will be crucial for the development of new therapies against human autoimmune and allergic diseases. Our lab is located at the Unit of Cell Imaging, IGC, Portugal.
Name: Ana Vaz
 
Position: M. Sc. Student
 
Project: “Effect of different types of Tregs in Experimental Autoimmune Encephalomyelitis (EAE)”
 
Brief description: Tregs are necessary to suppress the immune response against self-antigens. In my project I will compare the effect of MBP-specific Tregs versus Polyclonal-specific Tregs in the control of spontaneous EAE development and suppression of Th1/Th17 cells.




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Revision as of 03:33, 2 April 2009


Welcome!

Name: Ana Vaz

Position: M. Sc. Student

Project: “Effect of different types of Tregs in Experimental Autoimmune Encephalomyelitis (EAE)”

Brief description: Tregs are necessary to suppress the immune response against self-antigens. In my project I will compare the effect of MBP-specific Tregs versus Polyclonal-specific Tregs in the control of spontaneous EAE development and suppression of Th1/Th17 cells.


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