Prince:Intro to Mass Spectrometry Proteomics: Difference between revisions
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* [http://jcb.rupress.org/content/190/4/491.full.pdf+html Mass spectrometry–based proteomics in cell biology] - review by Walther & Mann | * [http://jcb.rupress.org/content/190/4/491.full.pdf+html Mass spectrometry–based proteomics in cell biology] - review by Walther & Mann | ||
* [http://www.springerlink.com/content/978-1-60761-443-2/ Proteome Bioinformatics] - book published in 2010, free pdfs available | * [http://www.springerlink.com/content/978-1-60761-443-2/ Proteome Bioinformatics] - book published in 2010, free pdfs available | ||
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Proteomics by Mass Spectrometry: Approaches, Advances, and Applications] (Yates, Ruse, and Nakorchevsky) | |||
===Relevant Hype=== | ===Relevant Hype=== | ||
* Yates, Ruse, and Nakorchevsky ([http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 see review above]) | |||
"Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics" | |||
* [http://archive.sciencewatch.com/march-april2007/sw_march-april2007_page3.htm Interview with Matthias Mann] (2007) | * [http://archive.sciencewatch.com/march-april2007/sw_march-april2007_page3.htm Interview with Matthias Mann] (2007) | ||
Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years? | Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years? | ||
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Q: Are there other applications we should keep our eyes out for? | Q: Are there other applications we should keep our eyes out for? | ||
A: … new field called "interaction proteomics" … see which proteins talk to which other proteins. | A: … new field called "interaction proteomics" … see which proteins talk to which other proteins. | ||
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Can Proteomics Retire the Western Blot?] (commentary by M. Mann) | |||
Revision as of 09:51, 21 September 2010
Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them.
- Mass spectrometry–based proteomics in cell biology - review by Walther & Mann
- Proteome Bioinformatics - book published in 2010, free pdfs available
- Proteomics by Mass Spectrometry: Approaches, Advances, and Applications (Yates, Ruse, and Nakorchevsky)
Relevant Hype
- Yates, Ruse, and Nakorchevsky (see review above)
"Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"
- Interview with Matthias Mann (2007)
Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years?
A: The future is now limitless … we can read out the proteome in a quantitative way, in a large-scale fashion…
We not only want to know what proteins are present in a sample, but also how they're modified…
Q: Are there other applications we should keep our eyes out for?
A: … new field called "interaction proteomics" … see which proteins talk to which other proteins.
- Can Proteomics Retire the Western Blot? (commentary by M. Mann)
