Prince:Intro to Mass Spectrometry Proteomics

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Current revision (15:37, 8 July 2013) (view source)
 
Line 11: Line 11:
* Matlab has a series of tutorials that are useful ('''>>doc help''' then search for '''Mass Spectrometry''')
* Matlab has a series of tutorials that are useful ('''>>doc help''' then search for '''Mass Spectrometry''')
-
===Relevant Hype===
+
===Misc===
 +
 
 +
* [http://www.ncbi.nlm.nih.gov/pubmed/17031796 Comments on standards in proteomics and the concept of fitness-for-purpose] - includes discussion of hypothesis driven and exploratory research.
 +
 
 +
===Statistics of Quantitative Proteomics===
 +
 
 +
* [http://www.ncbi.nlm.nih.gov/pubmed/17893850 Design and analysis issues in quantitative proteomics studies] Simple discussion of things like 'power', 'effect size' and multiple hypothesis testing.
 +
 
 +
===Hype===
* Yates, Ruse, and Nakorchevsky ([http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 see review above])
* Yates, Ruse, and Nakorchevsky ([http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 see review above])
     "Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"
     "Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"
* [http://archive.sciencewatch.com/march-april2007/sw_march-april2007_page3.htm Interview with Matthias Mann] (2007)
* [http://archive.sciencewatch.com/march-april2007/sw_march-april2007_page3.htm Interview with Matthias Mann] (2007)
-
    Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years?
 
-
      A: The future is now limitless … we can read out the proteome in a quantitative way, in a large-scale fashion…
 
-
        We not only want to know what proteins are present in a sample, but also how they're modified…
 
-
    Q: Are there other applications we should keep our eyes out for?
 
-
      A: … new field called "interaction proteomics" … see which proteins talk to which other proteins.
 
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Can Proteomics Retire the Western Blot?] (commentary by M. Mann)
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Can Proteomics Retire the Western Blot?] (commentary by M. Mann)

Current revision

Image:Prince lab logo.png

Home        Lab Members         Research         Publications         Internal         Mass Spec         Contact        


Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them.

Misc

Statistics of Quantitative Proteomics

Hype

   "Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"
Personal tools