Prince:Intro to Mass Spectrometry Proteomics

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Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them.

• Mass spectrometry–based proteomics in cell biology - review by Walther & Mann
• Proteome Bioinformatics - book published in 2010, free pdfs available
• Proteomics by Mass Spectrometry: Approaches, Advances, and Applications (Yates, Ruse, and Nakorchevsky)

Relevant Hype

• Yates, Ruse, and Nakorchevsky (see review above)

   "Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"

• Interview with Matthias Mann (2007)

   Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years?
     A: The future is now limitless … we can read out the proteome in a quantitative way, in a large-scale fashion… 
        We not only want to know what proteins are present in a sample, but also how they're modified…
   Q: Are there other applications we should keep our eyes out for?
     A: … new field called "interaction proteomics" … see which proteins talk to which other proteins.

• Can Proteomics Retire the Western Blot? (commentary by M. Mann)