Prince:Notebook/PPIX/Candidate Protein Pair: Difference between revisions
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==Potential Candidates== | ==Potential Candidates== | ||
* Gα/Gβ | |||
* JAK/STAT | * JAK/STAT | ||
* | * GRB2/SOS | ||
* SH2 domain?? | |||
* Phos/Jun | |||
* ERK2/MKP1 or MKP3 | |||
* R2-AKAP |
Revision as of 12:33, 21 April 2010
Properties
- Solved PDB binding structure
- There are ~20,000 structures with 2 chains on PDB, so plenty of candidates.
- Available in purified state
- Forms a complex in vivo
- Ideally, this would be manipulatable
- Available in affinity tag form for IP.
Potential Candidates
- Gα/Gβ
- JAK/STAT
- GRB2/SOS
- SH2 domain??
- Phos/Jun
- ERK2/MKP1 or MKP3
- R2-AKAP