Protein-protein interaction databases

From OpenWetWare

Revision as of 04:38, 23 September 2011

Name	Description	Link
String	database of experimental and predicted interactions	http://string-db.org/
IntAct	interactions derived from literature curation or direct user submissions	http://www.ebi.ac.uk/intact/
MIPS	Mammalian Protein-Protein Interaction Database (didn't work when tested in Sept '11)	http://mips.helmholtz-muenchen.de/proj/ppi/
cell 1	cell 2	cell 3
cell 1	cell 2	cell 3
cell 1	cell 2	cell 3

String

• collects evidence from genomic Context, high-throughput experiments, conserved coexpression, and text mining
• easy to learn how to use, great graphical interaction map, detailed explanation of evidence
• created by CPR, EMBL, SIB, KU, TUD, and UZH
• latest references: [1], [2]

IntAct

See also

On OpenWetWare

• The Prince lab present on OWW works on protein-protein interactions.
• OWW's Keating lab also works on protein-protein interactions.

Related literature searches

• search PubMed for MeSH term Protein Interaction Mapping [3], major topic [4], and reviews only [5]

Recent reviews:

• Databases of protein-protein interactions and complexes. Ooi et al. 2010
• Computational prediction of protein-protein interactions. Skrabanek et al. 2008
• ..the Human Proteotheque Initiative (HuPI). Coulombe et al. 2008