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| <div style="padding: 10px; color: #ffffff; background-color: #aaa; width: 730px">
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| <center>
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| [[Pruszak | <font face="trebuchet ms" style="color:#ffffff"> '''Home''' </font>]]
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| [[Pruszak:Research | <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]
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| [[Pruszak:Publications | <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]
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| [[Pruszak:Lab Members | <font face="trebuchet ms" style="color:#ffffff"> '''Lab Members''' </font>]]
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| [[Pruszak:P.I. | <font face="trebuchet ms" style="color:#ffffff"> '''P.I.''' </font>]]
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| [[Pruszak:Open Positions | <font face="trebuchet ms" style="color:#ffffff"> '''Open Positions''' </font>]]
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| [[Pruszak:Contact | <font face="trebuchet ms" style="color:#ffffff"> '''Contact''' </font>]]
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| </center>
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| </div><br>
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| <div style="padding: 10px; width: 720px; border: 3px solid #aaaaaa;">
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| Click on the highlighted titles or find papers on [http://www.ncbi.nlm.nih.gov/pubmed?term=Pruszak%20 PubMed].
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| == Original publications ==
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| '''1.'''
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| N. Hellbach, S.C. Weise, R. Vezzali, S.D. Wahane, S. Heidrich, D. Roidl, J.Pruszak, J.S. Esser, T. Vogel: [http://hmg.oxfordjournals.org/content/early/2014/07/01/hmg.ddu338.abstract Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome.] Human Molecular Genetics <b>2014</b> doi:10.1093/hmg/ddu338 <br/>
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| <br/>
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| '''2.'''
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| D.C. Schöndorf, M. Aureli, F.E. McAllister, C.J. Hindley, F. Mayer, B. Schmid, S.P. Sardi, M. Valsecchi, S. Hoffmann, L.K. Schwarz, U. Hedrich, D. Berg, L.S. Shihabuddin, J. Hu, J.Pruszak, S.P. Gygi, S. Sonnino,
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| T. Gasser, M. Deleidi: [http://www.nature.com/ncomms/2014/140606/ncomms5028/full/ncomms5028.html iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis.] Nature Communications <b>2014</b> 5: 4028. doi:10.1038/ncomms5028<br/>
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| <br/>
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| '''3.'''
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| G. Turaç, C.J. Hindley, R. Thomas, J.A. Davis, M. Deleidi, T. Gasser, E. Karaöz, J.Pruszak: <b>[http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068519 Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis.]</b> PLOS ONE <b>2013</b> 8(6): e68519. doi:10.1371/journal.pone.0068519<br/>
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| <br/>
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| '''4.'''
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| A. Rath, A. Klein, A. Papazoglou, J.Pruszak, J. Garcia, M. Krause, J. Maciaczyk, S.B. Dunnett, G. Nikkhah: [http://dx.doi.org/10.3727/096368912X654984 Survival and Functional Restoration of Human Fetal Ventral Mesencephalon Following Transplantation in a Rat Model of Parkinson's Disease.] Cell Transplantation <b>2013</b> 22(7):1281-93. <br/>
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| <br/>
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| '''5.'''
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| K. Schlegelmilch*, M. Mohseni*, O. Kirak, J.Pruszak, J.R. Rodriguez, D. Zhou, B.T. Kreger, V. Vasioukhin, J. Avruch, T.R. Brummelkamp, F.D. Camargo: [http://www.cell.com/abstract/S0092-8674%2811%2900183-8#Summary Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation.] Cell <b>2011</b> 144(5):782-95. <br/>
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| <br/>
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| '''6.'''
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| J.E. Carette*, J.Pruszak*, M. Varadarajan, V.A. Blomen, S. Gokhale, F.D. Camargo, M. Wernig, R. Jaenisch, T.R. Brummelkamp: <b>[http://bloodjournal.hematologylibrary.org/cgi/content/full/115/20/4039 Generation of iPSCs from cultured human malignant cells.]</b> Blood <b>2010</b> 115(20):4039-42. * equal contribution <br/>
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| <br/>
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| '''7.'''
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| S. Chung, A. Leung, B.S Han, M.Y. Chang, J.I. Moon, C.H. Kim, S. Hong, J.Pruszak, O. Isacson, K.S. Kim: [http://www.cell.com/cell-stem-cell/abstract/S1934-5909(09)00511-6 Wnt1-lmx1a Forms a Novel Autoregulatory Loop and Controls Midbrain Dopaminergic Differentiation Synergistically with the SHH-FoxA2 Pathway.] Cell Stem Cell <b>2009</b> 5(6):646-58.<br/>
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| <br/>
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| '''8.'''
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| J.Pruszak, W. Ludwig, A. Blak, K. Alavian, O. Isacson: <b>[http://onlinelibrary.wiley.com/doi/10.1002/stem.211/pdf CD15, CD24 and CD29 define a surface biomarker code for neural lineage differentiation of stem cells.]</b> Stem Cells <b>2009</b> 27(12):2928-40.<br/><br/>
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| '''9.'''
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| J.Pruszak, L. Just, O. Isacson, G. Nikkhah: [http://www.currentprotocols.com/protocol/sc02d05 Isolation and culture of ventral mesencephalic precursor cells and dopaminergic neurons from rodent brains.] Current Protocols in Stem Cell Biology <b>2009</b> 2D.5:1-21<br/>
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| <br/>
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| '''10.'''
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| H. Wakimoto, S. Kesari, C.J. Farrell, W.T. Curry WT, C. Zaupa, M. Aghi, T. Kuroda, A. Stemmer-Rachamimov, K. Shah, T.C. Liu, D.S. Jeyaretna, J. Debasitis, J.Pruszak, R.L. Martuza, S.D. Rabkin: [http://cancerres.aacrjournals.org/cgi/content/abstract/69/8/3472 Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors.] Cancer Research <b>2009</b> 69(8):3472-81.<br/>
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| <br/>
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| '''11.'''
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| M. Wernig, J.P. Zhao*, J.Pruszak*, E. Hedlund, D. Fu, F. Soldner, V. Broccoli, M. Constantine-Paton, O. Isacson, R. Jaenisch: <b>[http://www.pnas.org/content/105/15/5856.full.pdf+html Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease.]</b> PNAS <b>2008</b> 105(15):5856-61. * equal contribution<br/><br/>
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| '''12.'''
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| E.M. Hedlund, J.Pruszak, T. Lardaro, W. Ludwig, A. Viñuela, K.S. Kim, O. Isacson: [http://onlinelibrary.wiley.com/doi/10.1634/stemcells.2007-0996/abstract Embryonic Stem (ES) Cell-derived Pitx3-eGFP Midbrain Dopamine Neurons Survive Enrichment by FACS and Function in an Animal Model of Parkinson's Disease.] Stem Cells <b>2008</b> 26(6):1526-36.<br/><br/>
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| '''13.'''
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| J.Pruszak, K.C. Sonntag, M.H. Aung, R. Sanchez-Pernaute, O. Isacson: [http://onlinelibrary.wiley.com/doi/10.1634/stemcells.2006-0744/abstract Markers and Methods for Cell Sorting of Human Embryonic Stem Cell-derived Neural Cell Populations.] Stem Cells <b>2007</b> 25(9):2257-68.<br/><br/>
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| '''14.'''
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| G. Brunlid, J.Pruszak, B. Holmes, O. Isacson, K.C. Sonntag: [http://onlinelibrary.wiley.com/doi/10.1634/stemcells.2006-0745/abstract Immature and Neurally Differentiated Mouse ES Cells Do Not Express A Functional Fas/FasL System.] Stem Cells <b>2007</b> 25(10):2551-8.<br/><br/>
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| '''15.'''
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| E. Hedlund, J.Pruszak, A. Ferree, A. Viñuela, S. Hong, O. Isacson, K.S.Kim: [http://onlinelibrary.wiley.com/doi/10.1634/stemcells.2006-0540/abstract Selection of embryonic stem cell derived eGFP+ dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations.] Stem Cells <b>2007</b> 25(5):1126-35.<br/><br/>
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| '''16.'''
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| K.C. Sonntag, J.Pruszak, T. Yoshizaki, J. van Arensbergen, R. Sanchez-Pernaute, O. Isacson: [http://onlinelibrary.wiley.com/doi/10.1634/stemcells.2006-0380/pdf Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the BMP antagonist noggin.] Stem Cells <b>2007</b> 25(2):411-8.<br/><br/>
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| '''17.'''
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| S. Chung, B.S. Shin, E. Hedlund, J.Pruszak, O. Isacson et al.: [http://www.blackwell-synergy.com/doi/pdf/10.1111/j.1471-4159.2006.03841.x Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation.] J. Neurochem. <b>2006</b> 97(5):1467-80.<br/><br/>
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| '''18.'''
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| K.C. Sonntag, R. Simantov, L. Bjorklund, O. Cooper, J.Pruszak, F. Kowalke, J. Gilmartin, J. Ding, Y.P. Hu, M.M. Shen, O. Isacson: [http://neuroregeneration.org/PDF%20files/Sonntag%20et%20al%20MCN%202005.pdf Context-dependent neuronal differentiation and germ layer induction in Smad-/- and Cripto-/- embryonic stem cells.] Mol. Cell. Neurosci. <b>2005</b> 28(3):417-29.<br/><br/>
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|
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| == Reviews, book chapters, etc. ==
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| '''19.'''
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| V. Menon, R. Thomas, A. Ghale, C. Reinhard, J.Pruszak: [http://www.jove.com/video/52241 Flow cytometry protocols for surface and intracellular antigen analyses of neural cell types.] Journal of Visualized Experiments <b>2014</b> (94), e52241. [Video Article]
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| <br/><br/>
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| '''20.'''
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| J.Pruszak: [http://www.molcelltherapies.com/content/2/1/2 A brief perspective on neural cell therapy], Molecular and Cellular Therapies <b>2014</b> 2:2
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| <br/><br/>
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| '''21.'''
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| R. Thomas, J.Pruszak: [http://link.springer.com/chapter/10.1007/978-1-4614-8066-2_4 Current Research on Stem Cells in Parkinson’s Disease: Progress and Challenges.] [in: Turksen (ed.): "Stem Cells: Current Challenges and New Directions", Stem Cell Biology and Regenerative Medicine, 33:59-84, Springer <b>2013</b>]
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| <br/><br/>
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| '''22.'''
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| M. Döbrössy, J.Pruszak: [http://link.springer.com/protocol/10.1007/978-1-62703-505-7_7 Neural repair with pluripotent stem cells.] [in: Gourdie & Myers (eds.): "Wound Regeneration and Repair: Methods and Protocols, Methods in Molecular Biology", 1037:117-44, Springer <b>2013</b>]
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| <br/><br/>
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| '''23.'''
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| E. Lane, M. Sundberg, J.Pruszak: [http://onlinelibrary.wiley.com/doi/10.1002/3527600906.mcb.201100019/abstract Stem Cells and Parkinson's Disease.] Encyclopedia of Molecular Cell Biology and Molecular Medicine. <b>2012</b>
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| <br/><br/>
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| '''24.'''
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| V. Solozobova, N. Wyvekens, J.Pruszak: <b>[http://dx.doi.org/10.1007/s12015-012-9381-8 Lessons from the Embryonic Neural Stem Cell Niche for Neural Lineage Differentiation of Pluripotent Stem Cells.]</b> Stem Cell Reviews and Reports <b>2012</b> 8:813-829
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| <br/><br/>
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| '''25.'''
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| J.Pruszak, M. Döbrössy, J. Kieninger, K. Aravindalochanan, G.A. Urban, G. Nikkhah: [http://link.springer.com/chapter/10.1007/978-3-642-11865-4_20 Neural stem cells: from cell fate and metabolic monitoring toward clinical applications.] [in: Artmann, Minger & Hescheler (eds.): "Stem Cell Engineering: Principles and Applications", Springer <b>2011</b> 435-456.]<br/><br/>
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| '''26.'''
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| J.Pruszak: [http://jama.jamanetwork.com/article.aspx?articleid=186185 Dissection: Photographs of a Rite of Passage in American Medicine: 1880-1930. (Book and Media Reviews)] JAMA <b>2010</b> 304:218-220 <br/><br/>
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| '''27.'''
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| J.Pruszak, O. Isacson: <b>[http://link.springer.com/chapter/10.1007%2F978-1-4419-0322-8_11#page-1 Molecular and cellular determinants for generating ES-cell derived dopamine neurons for cell therapy.]</b> Advances in Experimental Medicine and Biology. <b>2009</b> 651:112-23. <br/><br/>
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| '''28.'''
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| J.Pruszak & O. Isacson: [http://onlinelibrary.wiley.com/book/10.1002/9780470511619 Directed Differentiation of Human Embryonic Stem Cells into Dopaminergic Neurons] [in: Sullivan, Cowan & Eggan (eds.): "Human Embryonic Stem Cells: The Practical Handbook"; Wiley <b>2007</b>]<br/><br/>
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| '''29.'''
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| S. Karki, J.Pruszak, O. Isacson, K. Sonntag: [http://www.jove.com/index/details.stp?ID=118 ES cell-derived neuroepithelial cell cultures] Journal of Visualized Experiments <b>2006</b> (1), e118. [Video Article]<br/><br/>
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| </div><br>
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