Quattrone

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Current revision (05:57, 2 December 2009) (view source)
 
(22 intermediate revisions not shown.)
Line 1: Line 1:
{{Quattrone}}
{{Quattrone}}
 +
<div style="width:910px; border-style:solid;border-left:1px solid;border-right:1px solid;border-top:0px;border-bottom:1px solid;border-color:#646700; padding: 5px;">
 +
<div style="font-family:verdana;font-stretch:condensed;font-size:12pt;color:#646700;">
 +
'''Welcome to the the Laboratory of Translational Genomics!<br>'''
 +
</div>
 +
<div style="font-family:verdana;font-stretch:condensed;font-size:9pt;">
 +
We are part of the '''CIBIO - Centre for Integrative Biology''' at the University of Trento, Italy<br>
 +
<br>'''Overview'''<br>
 +
The long-standing assumption that gene expression in eukaryotic cells is basically controlled at the transcriptional level is now progressively substituted by a scenario of regulation also largely dependent on complex networks of signals acting on mRNAs, which shape the proteome by changing mRNA accessibility to translation. This layer of regulation, which seems to be partially independent of transcriptional networks, is the general framework of activity of the laboratory. The laboratory is especially focused on the sequence-dependent translational control exerted by RRM-type RNA binding proteins on motifs located in the 3’ untranslated region of specific mRNAs.
 +
<br><br>
 +
'''Principal Investigator'''<br> Alessandro Quattrone, PhD<br>
 +
</div>
 +
</div>
[[Category:Lab]]
[[Category:Lab]]

Current revision

CIBIO    Home        Contact        Research        Lab Members        Publications        Talks       

Welcome to the the Laboratory of Translational Genomics!

We are part of the CIBIO - Centre for Integrative Biology at the University of Trento, Italy


Overview
The long-standing assumption that gene expression in eukaryotic cells is basically controlled at the transcriptional level is now progressively substituted by a scenario of regulation also largely dependent on complex networks of signals acting on mRNAs, which shape the proteome by changing mRNA accessibility to translation. This layer of regulation, which seems to be partially independent of transcriptional networks, is the general framework of activity of the laboratory. The laboratory is especially focused on the sequence-dependent translational control exerted by RRM-type RNA binding proteins on motifs located in the 3’ untranslated region of specific mRNAs.

Principal Investigator
Alessandro Quattrone, PhD

Personal tools