Raj Lab:Reading list

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Here's a list of papers that we think are interesting or useful (still very much a work in progress...):

Introduction to stochastic effects in gene expression

Error fetching PMID 2167833:
Error fetching PMID 12183631:
Error fetching PMID 11967532:
  1. Error fetching PMID 2167833: [ko-emboj-90]
    A surprisingly modern analysis of non-genetic variability in gene expression in mammalian cells.

  2. Error fetching PMID 12183631: [elowitz-science-02]
    A beautiful demonstration that variability in gene expression is intrinsically random.

  3. Error fetching PMID 11967532: [ozbudak-natgen-02]
    Perhaps the first demonstration of the dependence of variability upon biochemical parameters.

All Medline abstracts: PubMed HubMed

Numbers in biology

Error fetching PMID 911982:
Error fetching PMID 20018695:
  1. Error fetching PMID 911982: [berg-biophysj-77]
    A classic paper about the physical limits of receptor function.

  2. Error fetching PMID 20018695: [phillips-pnas-09]
    A really cool paper about the role that quantitative measurements can play in studying biology

All Medline abstracts: PubMed HubMed

Developmental biology

Error fetching PMID 2185858:
Error fetching PMID 17632062:
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Error fetching PMID 18497826:
  1. Error fetching PMID 2185858: [turing-ptrslb-52]
    This paper talks about how patterns can form from the spatial interactions between diffusing chemical species. Check out the date this paper was published: before the structure of DNA (this ref says 1953, but it was actually 1952)! Also, it's one of the first papers to recognize the role that computer simulations could play in studying these types of problems.

  2. Error fetching PMID 17632062: [gregor-cell-07]
  3. Error fetching PMID 16525464: [wernet-nature06]
    A technical tour de force in which the authors show that stochastic expression established the retinal mosaic in fruit flies.

  4. Error fetching PMID 18497826: [chang-nature08]
    In this paper, the authors show that stochastic lineage commitment is a result of transcriptome wide variability in gene expression. Cool!

All Medline abstracts: PubMed HubMed
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