Reactome & cMAP

This presentation from the BioMIBLab Summer 2006 Workshop is an imaging bioinformatics tool.

This presentation includes a comparison of the features of two bioinformatics tools, Reactome and cMAP.

Synopsis

Reactome

Curated resource of core pathways and reactions in human biology and 21 non-human species.

cMAP

A prototype system to access and link molecular profiles, molecular targets, targeted agents, and clinical data.

Features

Reactome

• Data model / Schema

consists of pathways, reactions, entities

• Search / Extended search

links to external references

• Pathfinder

finds pathways linked with input/output compounds

• Skypainter

identifies significant events linked with genes

• Downloads

manage local versions

• Editorial calendar

lists planned updates, curation information

cMAP

• Context

defines tissue and histology types

• Molecular profiles

displays expression ratios spatially in chromosomal and 2D array formats

• Molecular targets

organizes gene targets based on:

ontology (GO)

pathways (BioCARTA)

CMAP annotated pathways

• Targeted agents

found in CTEP, CMAP trials

• Clinical trials

Full Presentation

Reactome & cMAP PowerPoint Presentation

Links

cMAP Homepage

Reactome Homepage