Registry of Standard Biological Models/Basic Component Models/Ribosome binding site (RBS)

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ID: Ribosome Binding Site (RBS)

  • Description: RBS promoting translation rate
  • Hypothesis:
    • Continuous and constant translation rate
    • Unlimited resource for translation (ribosome, tRNA ...)
  • Inputs:
    • [mRNA]
  • Outputs:
    • protein-synthesis-rate
  • Characteristic parameters:
    • translation-rate-per-mRNA
RBS Brick Architecture

CellML structure (CellML 1.1 spec)

  • Component: RBS
  • Units:
    • TBD
  • Variables:
    • mRNA (public interface= in )
    • translationRatePermRNA (public interface = none / init value = XXX)
    • protein-synthesis-rate (public interface = out / init value = XXX)
  • MathML
    • <amsmath> proteinSynthesisRate = mRNA * translationRatePermRNA </amsmath>


Comments

  • this component provides the synthesis rate of downstream proteins based on [mRNA] and RBS translation rate.
  • don't know if it is possible to characterize experimentally the translationRatePermRNA?
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