Registry of Standard Biological Models/Basic Component Models/mRNA

ID: mRNA molecule

• Description: mRNA molecule
• Hypothesis:
  • mRNA molecules are produced following the binding of a promoter by a polymerase
  • mRNA production is continuous (no stochastic effect)
  • unlimited resources for transcription (excess of polymerases ...)
• Inputs:
  • PoPs-IN
• Outputs:
  • [mRNA]
• Internal parameters:
  • mRNA-degradation-rate

CellML structure (CellML 1.1 spec)

• Component: mRNA-molecule
• Units:
  • TBD
• Variables:
  • time (public interface = in)
  • PoPsIN (public interface = in )
  • mRNADegradationRate (public interface = none / init value = XXX)
  • mRNA (public interface = out / init value = 0.)
• MathML
  • <amsmath>\frac{d[mRNA]}{dtime} = PoPsIN - mRNA*mRNADegradationRate </amsmath>

Comments

• I feel uneasy with this component design as it is not a 'real' biobrick. I would like to encapsulate it into a higher level component, related to the coded protein.