Reiter

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==Research Interests==
 
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Thousands of functional RNA molecules exist in the human genome and do not encode protein
 
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sequences. We are just now beginning to understand how the diversity, structural complexity, and
 
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plasticity of regulatory RNAs help to drive evolution, development, and cellular differentiation. Indeed,
 
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it is the union of these non-coding RNAs with the capacity and efficiency of protein molecules that
 
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collectively serves to orchestrate and expand the complexity of an organism.
 
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Our research group applies macromolecular crystallography and NMR techniques to understand
 
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how RNA and protein (ribonucleoprotein (RNP)) complexes regulate gene expression. Protein-RNA
 
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recognition events are central to biology and misregulation of these interactions leads to human disease
 
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and oncogenesis. A key to understanding RNP biological function is having knowledge of how they
 
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assemble and are structured three-dimensionally.
 

Revision as of 19:34, 4 March 2012

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