Robert W Arnold Week 6: Difference between revisions
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#Amino acids 105-117 all form into a helix structure. | #Amino acids 105-117 all form into a helix structure. | ||
#The negatively charged amino acids are on the outsides of the protein, exposed. This protein is hydrophilic.... | #The negatively charged amino acids are on the outsides of the protein, exposed. This protein is hydrophilic.... | ||
#Program continued to freeze when trying to enlarge DNA for this question. Here is the frozen [[ | #Program continued to freeze when trying to enlarge DNA for this question. Here is the frozen [[Media:Picture 5.png | image.]] | ||
Revision as of 14:51, 5 October 2011
Electronic Lab Notebook
DNA Glycosylase Exercise
- Downloaded StarBioChem from MIT website.
- Played around with structure by switching angles and views.
- Made atoms 100% to sow accurate space-filled model.
- Began to answer exercise questions.
Questions
- Yes, I can identify the DNA and the hOGG1 protein. The DNA is the smaller, double helical structure attached to the space-filled hOGG1 protein.
- One of the amino acid sequences containing a sulfur atom is [CYS]241:A SG #2406. This means it is amino acid: cysteine; position; 241.
- The sulfur is on the side chain because it remained when backbone was unchecked, but disappeared when side chain was unchecked.
- The 13 amino acids from 105 to 117 are as follows:
- 105 - Threonine
- 106 - Leucine
- 107 - Alanine
- 108 - Glutamine
- 109 - Leucine
- 110 - Tyrosine
- 111 - Histidine
- 112 - Histidine
- 113 - Tryptophan
- 114 - Glycine
- 115 - Serine
- 116 - Valine
- 117 - Aspartic Acid
- Yes, helices are found in hOGG1, they are represented by a purplish pink color. Sheets are also found in hOGG1 and are represented by yellow. Coils are also found in a blueish color in the structure.
- Amino acids 105-117 all form into a helix structure.
- The negatively charged amino acids are on the outsides of the protein, exposed. This protein is hydrophilic....
- Program continued to freeze when trying to enlarge DNA for this question. Here is the frozen image.
