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Choudhary, S., White, J.C., Stoppel, W.L., Roberts, S.C. and Bhatia, S.R. (2011) Gelation behavior of polysaccharide-based interpenetrating polymer network (IPN) hydrogels. Rheologica Acta 50, 1-14. SpringerLink

Gaurav, V. and Roberts, S.C. (2011) Statistical optimization of single-cell production from Taxus cuspidata plant cell aggregates. Preparative Biochemistry and Biotechnology 41, 219-35. PubMed

Kolewe, M.E., Roberts, S.C., and Henson, M.A. (2011) A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnology and Bioengineering. PubMed

Kolewe, M.E., Henson, M.A. and Roberts, S.C. (2011) Analysis of Aggregate Size as a Process Variable Affecting Paclitaxel Accumulation in Taxus Suspension Cultures. Biotechnology Progress. PubMed

Stoppel, W.L., White, J.C., Horava, S.D., Bhatia, S.R. and Roberts, S.C. (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomaterialia 7, 3988-3998. PubMed


Gaurav, V., Kolewe, M.E. and Roberts, S.C. (2010) Flow Cytometric Methods to Investigate Culture Heterogeneities for Plant Metabolic Engineering. In: Plant Secondary Metabolism Engineering, Fett-Neto, A.G.G., Ed. In: Methods in Molecular Medicine 643 Humana Press, 243-262. PubMed

Kolewe, M.E., Henson, M.A. and Roberts, S.C. (2010) Characterization of aggregate size in Taxus suspension cell culture. Plant Cell Reports 29, 485-494. PubMed

Roberts, S. and Kolewe, M. (2010) Plant natural products from cultured multipotent cells. Nature Biotechnology 28, 1175-1176. Nature Biotechnology


Chin, K., Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2008) Hydrogel Perfluorocarbon Composite Scaffold Promotes Oxygen Transport to Immobilized Cells. Biotechnology progress 24, 358-366. PubMed

Kolewe, M.E., Gaurav, V. and Roberts, S.C. (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Molecular Pharmaceutics 5, 243-256. PubMed

McEntee, M.K.E., Bhatia, S.K., Tao, L., Roberts, S.C. and Bhatia, S.R. (2008) Tunable transport of glucose through ionically crosslinked alginate gels: Effect of alginate and calcium concentration. Journal of Applied Polymer Science 107, 2956-2962.


Khattak, S.F., Chin, K., Bhatia, S.R. and Roberts, S.C. (2007) Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnology and bioengineering 96, 156-166. PubMed

Roberts, S.C. (2007) Production and engineering of terpenoids in plant cell culture. Nature Chemical Biology 3, 387-395. PubMed

Vongpaseuth, K., Nims, E., Amand, M.S., Walker, E.L. and Roberts, S.C. (2007) Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture. Biotechnology Progress 23, 1180-1185. PubMed

Vongpaseuth, K. and Roberts, S.C. (2007) Advancements in the understanding of paclitaxel metabolism in tissue culture. Current Pharmaceutical Biotechnology 8, 219-236. PubMed


Khattak, S.F., Spatara, M., Roberts, L. and Roberts, S.C. (2006) Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnology letters 28, 1361-1370. PubMed

Nims, E., Dubois, C.P., Roberts, S.C. and Walker, E.L. (2006) Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metabolic Engineering 8, 385-394. PubMed


Agrawal, S.K., Chin, K.S., Sanabria-Delong, N., Aamer, K.A., Sardinha, H., Tew, G.N., Roberts, S.C. and Bhatia, S.R. (2005) Rheology and biocompatibility of poly (lactide)-poly (ethylene oxide)-poly (lactide) hydrogels.

Bhatia, S.R., Khattak, S.F. and Roberts, S.C. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51.

Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed

Naill, M.C. and Roberts, S.C. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed

Naill, M.C. and Roberts, S.C. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed

Naill, M.C. and Roberts, S.C. (2005) Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Reports 23, 528-533. PubMed

Naill, M.C. and Roberts, S.C. (2005) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnology Progress 21, 978-983. PubMed

Roberts, S.C. (2005) A successful introduction to chemical engineering first-semester course focusing on connection, communication and preparation. Chemical Engineering Education Summer 2005, 222-227.


Naill, M.C. and Roberts, S.C. (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826. PubMed


McAuliffe, G., Roberts, L.A., and Roberts, S.C. (2003) Paclitaxel administration and its effects on clinically relelvant human cancer and noncancer cell lines. Biotechnology Letters 24, 959-964.

Roberts, S.C., Naill, M., Gibson, D.M. and Shuler, M.L. (2003) A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports 21, 1217-1220. PubMed


Matthew, J.E., Nazario, Y.L., Roberts, S.C. and Bhatia, S.R. (2002) Effect of mammalian cell culture medium on the gelation properties of Pluronic® F127. Biomaterials 23, 4615-4619. PubMed

McAuliffe, G., Roberts, L. and Roberts, S. (2002) Paclitaxel administration and its effects on clinically relevant human cancer and non cancer cell lines. Biotechnology letters 24, 959-964.


Roberts, S. and Shuler, M. (1999) Strategies for bioproduct optimization in plant cell tissue cultures. BioHydrogen, 483-491.

Roberts, S.G. and Shuler, M.L. (1997) Large-scale plant cell culture. Current Opinion in Biotechnology 8, 154-159. PubMed

Srinivasan, V., Roberts, S.C. and Shuler, M.L. (1997) Combined use of six-well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: application to taxane production byTaxus sp. Plant Cell Reports 16, 600-604.

Pestchanker, L.J., Roberts, S.C. and Shuler, M.L. (1996) Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology 19, 256-260.

Srinivasan, V., Pestchanker, L., Moser, S., Hirasuna, T.J., Taticek, R.A. and Shuler, M.L. (1995) Taxol production in bioreactors: kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and bioengineering 47, 666-676.


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