Roberts:Publications

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Publications 2011 Wilson, S.A. and Roberts, S.C. (2011) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal. Wiley Online Library Choudhary, S., White, J.C., Stoppel, W.L., Roberts, S.C. and Bhatia, S.R. (2011) Gelation behavior of polysaccharide-based interpenetrating polymer network (IPN) hydrogels. Rheologica Acta 50, 1-14. SpringerLink Gaurav, V. and Roberts, S.C. (2011) Statistical optimization of single-cell production from Taxus cuspidata plant cell aggregates. Preparative Biochemistry and Biotechnology 41, 219-35. PubMed Kolewe, M.E., Roberts, S.C., and Henson, M.A. (2011) A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnology and Bioengineering. PubMed Kolewe, M.E., Henson, M.A. and Roberts, S.C. (2011) Analysis of Aggregate Size as a Process Variable Affecting Paclitaxel Accumulation in Taxus Suspension Cultures. Biotechnology Progress. PubMed Stoppel, W.L., White, J.C., Horava, S.D., Bhatia, S.R. and Roberts, S.C. (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomaterialia 7, 3988-3998. PubMed 2010 Gaurav, V., Kolewe, M.E. and Roberts, S.C. (2010) Flow Cytometric Methods to Investigate Culture Heterogeneities for Plant Metabolic Engineering. In: Plant Secondary Metabolism Engineering, Fett-Neto, A.G.G., Ed. In: Methods in Molecular Medicine 643 Humana Press, 243-262. PubMed Kolewe, M.E., Henson, M.A. and Roberts, S.C. (2010) Characterization of aggregate size in Taxus suspension cell culture. Plant Cell Reports 29, 485-494. PubMed Roberts, S. and Kolewe, M. (2010) Plant natural products from cultured multipotent cells. Nature Biotechnology 28, 1175-1176. Nature Biotechnology 2008 Chin, K., Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2008) Hydrogel Perfluorocarbon Composite Scaffold Promotes Oxygen Transport to Immobilized Cells. Biotechnology progress 24, 358-366. PubMed Kolewe, M.E., Gaurav, V. and Roberts, S.C. (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Molecular Pharmaceutics 5, 243-256. PubMed McEntee, M.K.E., Bhatia, S.K., Tao, L., Roberts, S.C. and Bhatia, S.R. (2008) Tunable transport of glucose through ionically crosslinked alginate gels: Effect of alginate and calcium concentration. Journal of Applied Polymer Science 107, 2956-2962. 2007 Khattak, S.F., Chin, K., Bhatia, S.R. and Roberts, S.C. (2007) Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnology and bioengineering 96, 156-166. PubMed Roberts, S.C. (2007) Production and engineering of terpenoids in plant cell culture. Nature Chemical Biology 3, 387-395. PubMed Vongpaseuth, K., Nims, E., Amand, M.S., Walker, E.L. and Roberts, S.C. (2007) Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture. Biotechnology Progress 23, 1180-1185. PubMed Vongpaseuth, K. and Roberts, S.C. (2007) Advancements in the understanding of paclitaxel metabolism in tissue culture. Current Pharmaceutical Biotechnology 8, 219-236. PubMed 2006 Khattak, S.F., Spatara, M., Roberts, L. and Roberts, S.C. (2006) Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnology letters 28, 1361-1370. PubMed Nims, E., Dubois, C.P., Roberts, S.C. and Walker, E.L. (2006) Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metabolic Engineering 8, 385-394. PubMed 2005 Agrawal, S.K., Chin, K.S., Sanabria-Delong, N., Aamer, K.A., Sardinha, H., Tew, G.N., Roberts, S.C. and Bhatia, S.R. (2005) Rheology and biocompatibility of poly (lactide)-poly (ethylene oxide)-poly (lactide) hydrogels. Bhatia, S.R., Khattak, S.F. and Roberts, S.C. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51. Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed Naill, M.C. and Roberts, S.C. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed Naill, M.C. and Roberts, S.C. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed Naill, M.C. and Roberts, S.C. (2005) Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Reports 23, 528-533. PubMed Naill, M.C. and Roberts, S.C. (2005) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnology Progress 21, 978-983. PubMed Roberts, S.C. (2005) A successful introduction to chemical engineering first-semester course focusing on connection, communication and preparation. Chemical Engineering Education Summer 2005, 222-227. 2004 Naill, M.C. and Roberts, S.C. (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826. PubMed 2003 McAuliffe, G., Roberts, L.A., and Roberts, S.C. (2003) Paclitaxel administration and its effects on clinically relelvant human cancer and noncancer cell lines. Biotechnology Letters 24, 959-964. Roberts, S.C., Naill, M., Gibson, D.M. and Shuler, M.L. (2003) A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports 21, 1217-1220. PubMed 2002 Matthew, J.E., Nazario, Y.L., Roberts, S.C. and Bhatia, S.R. (2002) Effect of mammalian cell culture medium on the gelation properties of Pluronic® F127. Biomaterials 23, 4615-4619. PubMed McAuliffe, G., Roberts, L. and Roberts, S. (2002) Paclitaxel administration and its effects on clinically relevant human cancer and non cancer cell lines. Biotechnology letters 24, 959-964. 1995-1999 Roberts, S. and Shuler, M. (1999) Strategies for bioproduct optimization in plant cell tissue cultures. BioHydrogen, 483-491. Roberts, S.G. and Shuler, M.L. (1997) Large-scale plant cell culture. Current Opinion in Biotechnology 8, 154-159. PubMed Srinivasan, V., Roberts, S.C. and Shuler, M.L. (1997) Combined use of six-well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: application to taxane production byTaxus sp. Plant Cell Reports 16, 600-604. Pestchanker, L.J., Roberts, S.C. and Shuler, M.L. (1996) Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology 19, 256-260. Srinivasan, V., Pestchanker, L., Moser, S., Hirasuna, T.J., Taticek, R.A. and Shuler, M.L. (1995) Taxol production in bioreactors: kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and bioengineering 47, 666-676.

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