Roberts:Publications

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Contents

Peer-Reviewed Publications


2011

Choudhary S, White JC, Stoppel WL, Roberts SC, and Bhatia SR. (2011) Gelation behavior of polysaccharide-based interpenetrating polymer network (IPN) hydrogels. Rheologica Acta 50, 1-14. SpringerLink

Gaurav V and Roberts SC. (2011) Statistical optimization of single-cell production from Taxus cuspidata plant cell aggregates. Preparative Biochemistry and Biotechnology 41, 219-35. PubMed

Kolewe ME, Roberts SC, and Henson MA. (2011) A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnology and Bioengineering. PubMed

Kolewe ME, Henson MA, and Roberts SC. (2011) Analysis of Aggregate Size as a Process Variable Affecting Paclitaxel Accumulation in Taxus Suspension Cultures. Biotechnology Progress. PubMed

Patil RA, Kolewe ME, Normanly J, Walker EL, and Roberts SC. (2011) Taxane biosynthetic pathway gene expression in Taxus suspension cultures with different bulk paclitaxel accumulation patterns & a molecular approach to understand variability in paclitaxel accumulation. Biotechnology Journal. PubMed

Stoppel WL, White JC, Horava SD, Bhatia SR, and Roberts SC. (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomaterialia 7, 3988-3998. PubMed

Wilson SA and Roberts SC. (2011) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal. PubMed

2010

Kolewe ME, Henson MA, and Roberts SC. (2010) Characterization of aggregate size in Taxus suspension cell culture. Plant Cell Reports 29, 485-494. PubMed

Roberts S and Kolewe ME. (2010) Plant natural products from cultured multipotent cells. Nature Biotechnology 28, 1175-1176. Nature Biotechnology

2008

Chin K, Khattak SF, Bhatia SR, and Roberts SC. (2008) Hydrogel Perfluorocarbon Composite Scaffold Promotes Oxygen Transport to Immobilized Cells. Biotechnology progress 24, 358-366. PubMed

Kolewe ME, Gaurav V, and Roberts SC. (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Molecular Pharmaceutics 5, 243-256. PubMed

McEntee MKE, Bhatia SK, Tao L, Roberts SC, and Bhatia SR. (2008) Tunable transport of glucose through ionically crosslinked alginate gels: Effect of alginate and calcium concentration. Journal of Applied Polymer Science 107, 2956-2962.

2007

Khattak SF, Chin K, Bhatia SR, and Roberts SC. (2007) Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnology and Bioengineering 96, 156-166. PubMed

Roberts SC. (2007) Production and engineering of terpenoids in plant cell culture. Nature Chemical Biology 3, 387-395. PubMed

Vongpaseuth K, Nims E, Amand MS, Walker EL, and Roberts SC. (2007) Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture. Biotechnology Progress 23, 1180-1185. PubMed

Vongpaseuth K, and Roberts SC. (2007) Advancements in the understanding of paclitaxel metabolism in tissue culture. Current Pharmaceutical Biotechnology 8, 219-236. PubMed

2006

Khattak, S.F., Spatara, M., Roberts, L. and Roberts, S.C. (2006) Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnology letters 28, 1361-1370. PubMed

Nims, E., Dubois, C.P., Roberts, S.C. and Walker, E.L. (2006) Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metabolic Engineering 8, 385-394. PubMed

2005

Agrawal, S.K., Chin, K.S., Sanabria-Delong, N., Aamer, K.A., Sardinha, H., Tew, G.N., Roberts, S.C. and Bhatia, S.R. (2005) Rheology and biocompatibility of poly (lactide)-poly (ethylene oxide)-poly (lactide) hydrogels.

Bhatia, S.R., Khattak, S.F. and Roberts, S.C. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51.

Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed

Naill, M.C. and Roberts, S.C. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed

Naill, M.C. and Roberts, S.C. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed

Naill, M.C. and Roberts, S.C. (2005) Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Reports 23, 528-533. PubMed

Naill, M.C. and Roberts, S.C. (2005) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnology Progress 21, 978-983. PubMed

Roberts, S.C. (2005) A successful introduction to chemical engineering first-semester course focusing on connection, communication and preparation. Chemical Engineering Education Summer 2005, 222-227.

2004

Naill, M.C. and Roberts, S.C. (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826. PubMed

2003

McAuliffe, G., Roberts, L.A., and Roberts, S.C. (2003) Paclitaxel administration and its effects on clinically relelvant human cancer and noncancer cell lines. Biotechnology Letters 24, 959-964.

Roberts, S.C., Naill, M., Gibson, D.M. and Shuler, M.L. (2003) A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports 21, 1217-1220. PubMed

2002

Matthew, J.E., Nazario, Y.L., Roberts, S.C. and Bhatia, S.R. (2002) Effect of mammalian cell culture medium on the gelation properties of Pluronic® F127. Biomaterials 23, 4615-4619. PubMed

McAuliffe, G., Roberts, L. and Roberts, S. (2002) Paclitaxel administration and its effects on clinically relevant human cancer and non cancer cell lines. Biotechnology letters 24, 959-964.

1995-1999

Roberts, S. and Shuler, M. (1999) Strategies for bioproduct optimization in plant cell tissue cultures. BioHydrogen, 483-491.

Roberts, S.G. and Shuler, M.L. (1997) Large-scale plant cell culture. Current Opinion in Biotechnology 8, 154-159. PubMed

Srinivasan V, Roberts SC, and Shuler ML. (1997) Combined use of six-well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: application to taxane production byTaxus sp. Plant Cell Reports 16, 600-604.

Pestchanker LJ, Roberts SC, and Shuler ML. (1996) Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology 19, 256-260.

Srinivasan V, Pestchanker L, Moser S, Hirasuna TJ, Taticek RA, and Shuler ML. (1995) Taxol production in bioreactors: kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and Bioengineering 47, 666-676.

Book Chapters

Stoppel WL and Roberts SC. (2011) Oxygen Supply in Tissue Engineering. In: Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications, Bhatia SK, Ed. Springer, 41-88. Springer

Gaurav V, Kolewe ME, and Roberts SC. (2010) Flow Cytometric Methods to Investigate Culture Heterogeneities for Plant Metabolic Engineering. In: Plant Secondary Metabolism Engineering, Fett-Neto AGG, Ed. In: Methods in Molecular Medicine 643 Humana Press, 243-262. PubMed


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