Kolewe ME, Roberts SC, and Henson MA. (2012) A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnology and Bioengineering 109, 472-482. PubMed
Lenka SK, Boutaoui N, Paulose B, Vongpaseuth K, Normanly J, Roberts SC, and Walker EL. (2012) Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells. BMC Genomics 13, 148. PubMed
McPartland TJ, Patil R, Malone MF, and Roberts SC. (2012) Liquid-Liquid extraction for recovery of paclitaxel from plant cell culture: solvent evaluation and use of extractants for partitioning and selectivity. Biotechnology Progress. PubMed
Patil RA, Kolewe ME, Normanly J, Walker EL, and Roberts SC. (2012) Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in Taxus suspension cultures. Biotechnology Journal 7, 418-427. PubMed
White JC, Stoppel WL, Roberts SC, and Bhatia SR. (2012) Addition of perflurocarbons to alginate hydrogels significantly impacts molecular transport and fracture stress. Journal of Biomedical Materials Research Part A. accepted.
Wilson SA and Roberts SC. (2012) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal 10, 249-268. PubMed
Choudhary S, White JC, Stoppel WL, Roberts SC, and Bhatia SR. (2011) Gelation behavior of polysaccharide-based interpenetrating polymer network (IPN) hydrogels. Rheologica Acta 50, 1-14. SpringerLink
Gaurav V and Roberts SC. (2011) Statistical optimization of single-cell production from Taxus cuspidata plant cell aggregates. Preparative Biochemistry and Biotechnology 41, 219-35. PubMed
Kolewe ME, Henson MA, and Roberts SC. (2011) Analysis of Aggregate Size as a Process Variable Affecting Paclitaxel Accumulation in Taxus Suspension Cultures. Biotechnology Progress 27, 1365–1372. PubMed
Stoppel WL, White JC, Horava SD, Bhatia SR, and Roberts SC. (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomaterialia 7, 3988-3998. PubMed
Kolewe ME, Henson MA, and Roberts SC. (2010) Characterization of aggregate size in Taxus suspension cell culture. Plant Cell Reports 29, 485-494. PubMed
Roberts S and Kolewe ME. (2010) Plant natural products from cultured multipotent cells. Nature Biotechnology 28, 1175-1176. Nature Biotechnology
Chin K, Khattak SF, Bhatia SR, and Roberts SC. (2008) Hydrogel Perfluorocarbon Composite Scaffold Promotes Oxygen Transport to Immobilized Cells. Biotechnology progress 24, 358-366. PubMed
Kolewe ME, Gaurav V, and Roberts SC. (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Molecular Pharmaceutics 5, 243-256. PubMed
McEntee MKE, Bhatia SK, Tao L, Roberts SC, and Bhatia SR. (2008) Tunable transport of glucose through ionically crosslinked alginate gels: Effect of alginate and calcium concentration. Journal of Applied Polymer Science 107, 2956-2962.
Khattak SF, Chin K, Bhatia SR, and Roberts SC. (2007) Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnology and Bioengineering 96, 156-166. PubMed
Roberts SC. (2007) Production and engineering of terpenoids in plant cell culture. Nature Chemical Biology 3, 387-395. PubMed
Vongpaseuth K, Nims E, Amand MS, Walker EL, and Roberts SC. (2007) Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture. Biotechnology Progress 23, 1180-1185. PubMed
Vongpaseuth K, and Roberts SC. (2007) Advancements in the understanding of paclitaxel metabolism in tissue culture. Current Pharmaceutical Biotechnology 8, 219-236. PubMed
Khattak, S.F., Spatara, M., Roberts, L. and Roberts, S.C. (2006) Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnology letters 28, 1361-1370. PubMed
Nims, E., Dubois, C.P., Roberts, S.C. and Walker, E.L. (2006) Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metabolic Engineering 8, 385-394. PubMed
Bhatia SR, Khattak SF, and Roberts SC. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51. ScienceDirect
Khattak SF, Bhatia SR, and Roberts SC. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed
Naill MC and Roberts SC. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed
Naill MC and Roberts SC. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed
Naill MC and Roberts SC. (2005) Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Reports 23, 528-533. PubMed
Naill MC and Roberts SC. (2005) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnology Progress 21, 978-983. PubMed
Roberts SC. (2005) A successful introduction to chemical engineering first-semester course focusing on connection, communication and preparation. Chemical Engineering Education Summer 2005, 222-227. ChE Education
Naill MC and Roberts SC. (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826. PubMed
McAuliffe G, Roberts LA, and Roberts SC. (2003) Paclitaxel administration and its effects on clinically relelvant human cancer and noncancer cell lines. Biotechnology Letters 24, 959-964.
Roberts SC, Naill M, Gibson DM, and Shuler ML. (2003) A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports 21, 1217-1220. PubMed
Matthew JE, Nazario YL, Roberts SC and Bhatia SR. (2002) Effect of mammalian cell culture medium on the gelation properties of Pluronic® F127. Biomaterials 23, 4615-4619. PubMed
McAuliffe G, Roberts L, and Roberts SC. (2002) Paclitaxel administration and its effects on clinically relevant human cancer and non cancer cell lines. Biotechnology Letters 24, 959-964.
2001 and Older
Roberts, S.G. and Shuler, M.L. (1997) Large-scale plant cell culture. Current Opinion in Biotechnology 8, 154-159. PubMed
Srinivasan V, Roberts SC, and Shuler ML. (1997) Combined use of six-well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: application to taxane production byTaxus sp. Plant Cell Reports 16, 600-604.
Pestchanker LJ, Roberts SC, and Shuler ML. (1996) Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology 19, 256-260.
Srinivasan V, Pestchanker L, Moser S, Hirasuna TJ, Taticek RA, and Shuler ML. (1995) Taxol production in bioreactors: kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and Bioengineering 47, 666-676.
Patil RA and Roberts SC. (2011) Implications of cellular heterogeneity on plant cell culture performance. In: Biotechnology for Medicinal Plants, Chandra S, Lata H, and Varma A, Eds. Springer, submitted October 2011.
Stoppel WL and Roberts SC. (2011) Oxygen Supply in Tissue Engineering. In: Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications, Bhatia SK, Ed. Springer, 41-88. Springer
Gaurav V, Kolewe ME, and Roberts SC. (2010) Flow Cytometric Methods to Investigate Culture Heterogeneities for Plant Metabolic Engineering. In: Plant Secondary Metabolism Engineering, Fett-Neto AGG, Ed. In: Methods in Molecular Medicine 643 Humana Press, 243-262. PubMed
Roberts SC and Shuler M. (1998) Strategies for Bioproduct Optimization in Plant Cell Tissue Cultures. In: BioHydrogen, Zaborsky E, Ed. Plenum Press, New York, 483-492. Springer