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===Introduction===
==Introduction==


We intend to use this space to seed, prioritize and sustain a list of  'Top 10 gaps' in our practice of synthetic biology for this group - and others - to consider, discuss, and work towards addressing.  We ideally hope to produce from the discussions documented and materials collected here a series of simple, digestible co-authored papers summarizing each gap, current practices, open questions, and recommendations for moving forward.
We intend to use this space to seed, prioritize and sustain a list of  'Top gaps' in the practice of synthetic biology for this group - and others - to consider, discuss, and work towards addressing.  We ideally hope to produce from the discussions documented and materials collected here a simple, digestible co-authored paper, or papers, summarizing each gap, current practices, open questions, and recommendations for moving forward.


===Gaps to Mind===
==Current Gap List==


Please use this space to suggest and describe new or existing gaps, needs or issues in our practice of synthetic biology. Please add any relevant information, articles, contacts or other resources.
[[SBPWG:Gaps/Gaps_Draft_v4 | Gaps List v4 SynBERC Fall Retreat]]: Gaps Presented and Gathered at the SynBERC Fall Retreat


====Gap Seed List====
==Previous Gap List Drafts and References==


All these to be refined. Edit ruthlessly. Add comments, references, examples - anything that will be helpful!
[[SBPWG:Gaps/Gaps_Draft_v3 | Gap Seed List v3 - July 27th for Working Group Meeting ]]: Gap seed list used for discussion at the July 27th Working Group Meeting - combines elements of several drafts from below. Please edit!


[[SBPWG:Gaps/Gaps_Draft_v2 | Gap Seed List v2 - July 22nd for SAB Call ]]: Gap seed list drafted for feedback from the SynBERC SAB


Emergence of DIY & Implications for Safety, Security
[https://spreadsheets.google.com/spreadsheet/viewform?formkey=dGp3ZXp5MHhrRW84YUNHRVN4b0tYeUE6MQ Wilson ELSI Issues Survey] Link to the Wilson Center's list of critical ELSI issues related to Synthetic Biology. They are expanding this list via an on-line survey, and after gathering additional ideas  will be posting an online poll to allow people to prioritize the most important issues.
* Should there be similar expectations of responsible conduct between institutional and non-institutional actors?


[[SBPWG:Gaps/Gaps_Draft_v1 | Gap Seed List v1 - June 30th 2011 ]]: Gap seed list first outlined by participants of the June 30th 2011 Working Group Meeting:


Preparedness for Syn Bio (-Labeled) Accidents
[http://celect.lids.mit.edu/ Select] is a potential tool for prioritizing gaps
* Do we have a community response plan? Who will be held accountable?
* http://www.nature.com/nbt/journal/v27/n12/full/nbt1209-1109.html
 
 
Developing Trust in a World of Profits and Secrets
* How can we be ambassadors for biosafety when we do not have knowledge of research ongoing at private companies and in secure govt labs?
 
 
Ownership, Sharing and Innovation - Property Rights Frameworks for Synthetic Biology
* At what level in the abstraction hierarchy of envisioned biological designs should we instill property rights?
 
 
Educating and Inspiring Leadership in Pratices
* How savy should we expect researchers to be wrt the broader context of technology developments?
* How do deal with generational transfer of knowledge and immigration from a broad array of disciplines?
 
 
Testing Engineered Biological Designs in the 'Real World'
* What are appropriate risk assessment frameworks for intentional & unintentional environmental release?
* How do we approach regulation of cross-cutting technology platforms spanning multiple disjointed regulatory bodies set primarily by application area?
* Can we develop experimental systems for assessing safety?
* e.g. rE.Coli
 
 
Economic Forecasting for Synthetic Biology Technology Developments
* What are our near-term vs long-term deliverables and how does syn bio fit into biotechnology developments at large?
 
 
Establishing Meaningful Dialogues with Diverse Stakeholders
* How can companies anticipate and respond proactively to public/soceital sentiments on biotechnology?
* e.g. ETC group letter to SB5
 
 
How can deliver reliable information about synthetic biology to the publics?
* e.g. FactCheck.org for synthetic biology as recommended by the PCSBI
* e.g. Climate Scientists Page: http://www.realclimate.org/
 
Risk Governance
* http://www.irgc.org/IMG/pdf/irgc_SB_final_07jan_web.pdf

Latest revision as of 07:39, 24 September 2011

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Introduction

We intend to use this space to seed, prioritize and sustain a list of 'Top gaps' in the practice of synthetic biology for this group - and others - to consider, discuss, and work towards addressing. We ideally hope to produce from the discussions documented and materials collected here a simple, digestible co-authored paper, or papers, summarizing each gap, current practices, open questions, and recommendations for moving forward.

Current Gap List

Gaps List v4 SynBERC Fall Retreat: Gaps Presented and Gathered at the SynBERC Fall Retreat

Previous Gap List Drafts and References

Gap Seed List v3 - July 27th for Working Group Meeting : Gap seed list used for discussion at the July 27th Working Group Meeting - combines elements of several drafts from below. Please edit!

Gap Seed List v2 - July 22nd for SAB Call : Gap seed list drafted for feedback from the SynBERC SAB

Wilson ELSI Issues Survey Link to the Wilson Center's list of critical ELSI issues related to Synthetic Biology. They are expanding this list via an on-line survey, and after gathering additional ideas will be posting an online poll to allow people to prioritize the most important issues.

Gap Seed List v1 - June 30th 2011 : Gap seed list first outlined by participants of the June 30th 2011 Working Group Meeting:

Select is a potential tool for prioritizing gaps

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