Saeij lab
OverviewThe primary research interest of our laboratory is to understand how intracellular parasites exploit and manipulate the host cells in which they live to ensure their survival, replication and transmission and hence their success. Our experimental model is Toxoplasma gondii, considered the most successful protozoan parasite of warm-blooded animals. The focus of my laboratory over the last years has been to identify genes of Toxoplasma that determine virulence, host genes and pathways that determine resistance/susceptibility, and to characterize their specific interactions. To achieve this we use a combination of genomics, biochemistry, genetics, microscopy, immunology and computational tools.
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