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| *Robinson, M.A., Park, S., Sun, Z.Y., Silver, P.A., Wagner,
| | Back to the [[Silver_Lab | Silver Lab]] |
| G., and Hogle, J.M. Multiple conformations in the ligand-binding
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| site of the yeast nuclear pore targeting domain of Nup116p '''J.
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| Biol. Chem. '''2005. Aug 16. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16105837&query_hl=1 Abstract]
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| *Brodsky, A.S., Meyer, C.A., Hall, G., Swinburne, I.A., Keenan,
| | [[Silver: Publications (2000-)| 2000 to present]] |
| B.J., Liu, X.S., Fox, E.A., and., Silver, P.A. Genomic mapping
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| of RNA Polymerase II reveals sites of co-transcriptional regulation
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| in human cells. ‘‘‘Genome Biology. ‘‘‘2005. Jul 15:6(8): R64
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| [http://genomebiology.com/2005/6/8/R64/abstract Abstract]
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| *McKee, A.E., Minet, E., Stern, C., Riahi, S., Stiles, C.D.,
| | [[Silver: Publications (1990-1999) | 1990-1999]] |
| and., Silver, P.A. A genome-wide in situ hybridization map of
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| RNA-binding proteins reveals anatomically restricted expression
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| in the developing mouse brain. ‘‘‘BMC Dev Biol. ‘‘‘2005. July
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| 20;5(1):14 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16033648&query_hl=1 Abstract]
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| *Carrol, J.S., Liu, X.S., C.R., Brodsky, A.S., Meyer, C.A.,
| | [[Silver: Publications (By subject) | By Subject Matter]] - in progress |
| Li, W., Szary, A., Shao, W., Hesterman, E., Geistlinger, T.R.,
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| Fox, E.A., Silver, P.A., and Brown, M. Chromosome-wide mapping
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| of estrogen receptor binding reveals long-range combinatorial
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| regulation requiring forkhead proteins. ‘‘‘Cell. ‘‘‘2005. July
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| 15;122(1):33-43 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16009131&query_hl=1 Abstract]
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| *Park, S., Isaacson, R., Kim, H.T., Silver, P.A., and Wagner,
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| G. Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin
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| interaction sites. ‘‘‘Structure (Camb) ‘‘‘2005. Jul; 13(7):995-1005. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15844952&query_hl=1 Abstract]
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| *Casolari, J.M., Brown, C.R., Drubin, D.A., Rando, O.J., and
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| Silver, P.A. Developmentally induced changes in transcriptional
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| program alter spatial organization across chromosomes. ‘‘‘Genes
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| Dev. ‘‘‘2005. May 15;19(10):1188-98. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15905407&query_hl=1 Abstract]
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| *Schroeder, F.C., Kau, T.R., Silver, P.A., and Clardy, J. The
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| psammaplysenes, specific inhibitors of FOXO1a nuclear export.
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| ‘‘‘J Nat Prod ‘‘‘2005. Apr; 68(4):574-6. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15844952&query_hl=1 Abstract]
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| *Devroe, E., Silver, P.A., and Engelman, A. HIV-1 incorporates
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| and proteolytically processes human NDR1 and NDR2 serien-threonine
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| kinases. ‘‘‘Virology ‘‘‘2005. Jan 5; 331(1):181-9. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15582665 Abstract]
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| *Hieronymus, H., and Silver, P.A. A systems view of mRNP biology.
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| ‘‘‘Genes Dev. ‘‘‘2004. Dec 1,18(23):2845-60.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15574591 Abstract]
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| *Lu, R., Limon, A., Devroe, E., Cherepanov, P., Silver, P.A.,
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| and Engelman, Class II integrase mutants with changes in putative
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| nuclear localization signals are primarily blocked at a post-nuclear
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| entry step of human immunodeficiency virus type 1 replication.
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| ‘‘‘J. Virol. ‘‘‘2004. Dec; 78(23):12735-46.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15542626 Abstract]
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| *Hieronymus, H., Yu, M.C., and Silver, P.A. Genome-wide mRNA
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| surveillance is coupled to the mRNA export. ‘‘‘Genes Dev. ‘‘‘2004.
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| Nov 1; 18(21):2652-62.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15489286 Abstract]
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| *Silver, P.A. and Way, Jeffrey. The potential for synthetic
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| biology. ‘‘‘The Scientist.’’’ 2004. Sept. 27; 18(18);30-1.<A
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| HREF="http://www.the-scientist.com/yr2004/sep/research2_040927.html">
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| </A>[silver%26way.pdf">Downloading PDF</A>
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| *Cherepanov, P., Devroe, E., Silver, P.A., and Engelman, A.
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| Identification of an evolutionarily-conserved domain in LEDGF/p75
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| that binds HIV-1 integrase. ‘‘‘J. Biol. Chem. ‘‘‘2004; Sept.
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| 14 [Epub ahead of print]. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15371438 Abstract]
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| *Turlure, F., Devroe, E., Silver, P.A., and Engelman, A. Human
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| cell proteins and human immunodeficiency virus DNA integration.
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| ‘‘‘Front Biosci. ‘‘‘2004; Sept. 1; 9:3187-208. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15353349 Abstract]
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| *Yu, M.C., Bachand F., McBride, A.E., Komili, S., Casolari,
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| J.M., and Silver, P.A. Arginine methyltransferase affects interactions
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| and recruitment of mRNA processing and export factors. ‘‘‘Genes
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| Dev<I>.</I>‘‘‘ 2004, Aug. 15. 18(16):2024-35. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15314027 Abstract]
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| *McKee A.E.. and Silver, P.A. REF-ereeing the cytoplasmic fate
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| of mRNA via nuclear export. ‘‘‘Dev Cell<I>.</I>‘‘‘ 2004. July
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| 7; 23(13):2641-50.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15177019 Abstract]
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| *Bachand, F. and Silver, P.A. PRMT3 is a ribosomal protein
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| methyltransferase that affects the cellular levels of ribosomal
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| subunits. ‘‘‘EMBO J<I>.</I>‘‘‘ 2004. July 7; 23(13):2641-50.<A
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| HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15175657 Abstract]
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| *Casolari, J.M., Brown, C.R., Komili, S., West, J., Hieronymus,
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| H., and Silver, P.A. Genome-wide localization of the nuclear
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| transport machinery reveals coupling of transcriptional status
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| and nuclear organization. ‘‘‘Cell<I>.</I>‘‘‘ 2004. May 14; 117(4):427-39.<A
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| HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15137937 Abstract]
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| *Casolari, J.M. and Silver, P.A. Guardian at the gate: preventing
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| unspliced pre-mRNA export. ‘‘‘Trends Cell B iol<I>.</I>‘‘‘ 2004.
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| May, 14(5):222-5 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15130577 Abstract]
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| *Devroe, E., Erdjument-Bromage, H., Tempst, P., and Silver,
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| P.A. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine
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| kinases. ‘‘‘JBC<I>.</I>‘‘‘ April 2, 2004. [http://www.jbc.org/cgi/content/abstract/M401999200v1 Abstract]
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| *Devroe, E., and Silver, P.A. Therapeutic potential of retroviral
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| RNAi vectors ‘‘‘Expert Opin. Biol. Ther. ‘‘‘2004; 4(3):319-27.
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| [Devroe_EOBT.pdf">Downloading PDF</A>
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| *Kau, T.R., Way, J.C., and Silver, P.A. Nuclear transport and
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| cancer: from mechanism to intervention. ‘‘‘Nat. Rev. Cancer.
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| ‘‘‘2004; Feb; 4(2):106-17. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14732865 Abstract]
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| *Jiang, Y., Minet, E., Zhang, Z., Silver, P.A., and Bai, M.
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| Modulation of interprotomer relationship is important for activation
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| of dimeric calcium-sensing receptor. ‘‘‘J. Biol. Chem. ‘‘‘2004.’’’
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| ‘‘‘[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14729680 Abstract]
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| *Kau, T.R., Schroeder, F., Ramazwamy, S., Wojciechowski, C.L.,
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| Zhao, J.J., Roberts, T.M., Clardy, J., Sellers, W.R., and Silver,
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| P.A. A Chemical genetic screen identifies inhibitors of regulated
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| nuclear export of a Forkhead transcription factor in PTEN deficient
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| tumor cells. ‘‘‘Cancer Cell. ‘‘‘2003; 4(6):463-76. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14706338 Abstract]
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| *Haggarty, S.J., Koeller, K.M., Kau, T.R., Silver, P.A., Roberge,
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| M., and Schreiber, S.L. Small molecule modulation of the human
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| chromatid decatenation checkpoint. ‘‘‘Chem. Biol. ‘‘‘2003; 10(12):1267-79.
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| [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14700634 Abstract]
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| *Hitchcock, A.L., Auld, K., Gygi, S.P., and Silver, P.A. A
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| subset of membrane-associated proteins is ubiquitinated in response
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| to mutations in the endoplasmic reticulum degradation machinery.
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| ‘‘‘Proc. Nat. Acad. Sci’’’.’’’ ‘‘‘2003, 100(22):12735-40.<A
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| HREF="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14557538&dopt=Abstract">
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| Abstract</A>
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| *Devroe, E., Engelman, A., and Silver, P.A. Intracellular transport
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| of human immunodeficiency virus type 1 integrase ‘‘‘J. Cell.
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| Sci. ‘‘‘2003; 116(Pt21):4401-8. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=13130095&dopt=Abstract Abstract]
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| *Brodsky, A.S,, Johnston, A.P,, Trau, M., and Silver, P.A.
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| Analysis of RNA-protein interactions by flow cytometry. ‘‘‘Curr.
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| Opin. Mol. Ther ‘‘‘2003; 5(3):235-40. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12870432&dopt=Abstract Abstract]
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| *Kau, T.R. and Silver, P.A. Nuclear transport as a target for
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| cell growth. ‘‘‘Drug Discov. Today. ‘‘‘2003; 8(2):78-85. <A
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| HREF="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12565010&dopt=Abstract Abstract]
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| *Hieronymus, H. and Silver, P.A. Genome-wide analysis of RNA-protein
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| interactions illustrates specificity of the mRNA export machinery.
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| ‘‘‘Nat. Genet. ‘‘‘2003; 33(2):155-61. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12524544&dopt=Abstract Abstract]
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| *Beilharz T., Egan, B., Silver, P.A. Hofmann, K., and Lithgow,
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| T. Bipartite signals mediate subcellular targeting of tail-anchored
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| membrane protein in saccharomyces cerevisiae. ‘‘‘J. Biol. Chem.
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| ‘‘‘2003; [epub ahead of print].[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12514182&dopt=Abstract">
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| Abstract</A>
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| *Damelin, M. and Silver, P.A. In situ analysis of spatial relationships
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| between proteins of the nuclear pore complex. ‘‘‘Biophys J. ‘‘‘2002;
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| 83(6): 3626-36.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12496130&dopt=Abstract">
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| Abstract</A>
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| *Brodsky, A.S. and Silver, P.A. A microbead-based system for
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| identifying and characterizing RNA-protein interactions by flow
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| cytometry. ‘‘‘Mol Cell Proteomics ‘‘‘2002; 1(12): 922-9. <A
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| HREF="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12543929&dopt=Abstract Abstract]
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| | |
| *Lei, E.P., Stern, C.A., Fahrenkrog, B., Krebber, H., Moy,
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| T.I., Aebi, U. and Silver, P.A., Sac3 is an mRNA export factor
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| that localizes to the cytoplasmic fibrils of the nuclear pore
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| complex. ‘‘‘Mol Biol Cell ‘‘‘2002; <I>In Press.</I>
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| *Lei, E. P. and Silver, P.A. Intron status and 3'-end formation
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| control cotranscriptional export of mRNA. ‘‘‘Genes Dev ‘‘‘2002;
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| 16: 2761-2766. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12414728&dopt=Abstract Abstract]
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| | |
| *Limon A., Devroe, E., Lu, R., Ghory, H.Z., Silver, P.A., and
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| Engelman, A. Nuclear localization of human immunodeficiency virus
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| type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic
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| integrase mutants primarily defective for integration, not PIC
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| nuclear import. ‘‘‘J Virol. ‘‘‘2002; 76(21): 10598-607.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12368302&dopt=Abstract">
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| Abstract</A>
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| *Devroe, E. and Silver, P.A. Retrovirus-delivered siRNA. ‘‘‘BMC
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| Biotechnol. ‘‘‘2002; 2(1): 15. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12199908&dopt=Abstract Abstract]
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| *Moy, T.I., and Silver, P.A. Requirements for the nuclear export
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| of the small ribosomal subunit. ‘‘‘J Cell Sci ‘‘‘2002; 115 (Pt
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| 14): 2985-95.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12082158&dopt=Abstract">
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| Abstract</A>
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| *Damelin, M., Silver, P.A., and Corbett, A.H. Nuclear protein
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| transport. ‘‘‘Methods Enzymol. ‘‘‘2002; 351:587-607.
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| *Brodsky, A..S. and Silver, P.A. Identifying proteins that
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| affect mRNA localization in living cells. ‘‘‘Methods ‘‘‘2002;
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| 26(2):151-5.
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| *Moy, T.I., Boettner, D., Rhodes, J.C., Silver, P.A., and Askew,
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| D.S. Identification of a role for Saccharomyces cerevisiae Cgr1p
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| in pre-rRNA processing and 60S ribosome subunit synthesis. ‘‘‘Microbiology
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| ‘‘‘2002; 148 (Pt 4): 1081-1090. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11932453&dopt=Abstract Abstract]
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| *Damelin, M., Simon, I., Moy, T.I., Wilson, B., Komili, S.,
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| Tempst, P., Roth, F.P., Young, R.A., Carins, B.R., and Silver,
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| P.A. The genome-wide localization of Rsc9, a component of the
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| RSC chromatin-remodeling complex, changes in response to stress.
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| ‘‘‘Mol Cell ‘‘‘2002; 9 (3): 563-73. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11931764&dopt=Abstract Abstract]
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| *Lei, E.P. and Silver, P.A. Protein and RNA export from the
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| nucleus. ‘‘‘Dev Cell. ‘‘‘2002; 2 (3): 261-72. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11879632&dopt=Abstract Abstract]
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| *Valentini, S.R., Casolari, J.M., Oliveira, C.C., Silver, P.A.
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| and McBride, A.E. Genetic interactions of yeast eukaryotic translation
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| initiation factor 5A (eIF5A) reveal connections to poly(A)-binding
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| protein and protein kinase C signaling. ‘‘‘Genetics ‘‘‘2002;
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| 160 (2): 393-405. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11861547&dopt=Abstract Abstract]
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| *Hitchcock, A.L., Krebber, H., Frietze, S., Lin, A., Latterich,
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| M., and Silver, P.A. The conserved Npl4 protein complex mediates
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| proteasome-dependent membrane-bound transcription factor activation.
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| ‘‘‘Mol Biol Cell ‘‘‘2001; 12 (10): 3226-3241. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11598205&dopt=Abstract Abstract]
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| *Lei, E.P., Krebber, H., and Silver, P.A. Messenger RNAs are
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| recruited for nuclear export during transcription. ‘‘‘Genes Dev.
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| ‘‘‘2001; 15(14): 1771-1782. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11459827&dopt=Abstract Abstract]
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| | |
| *McBride, A.E. and Silver, P.A. State of the Arg: Protein methylation
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| at arginine comes of age. ‘‘‘Cell ‘‘‘2001; 106(1): 5-8.
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| *Tham, W., Wyithe, J.S., Ferrigno, P.K., Silver, P.A., and
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| Zakian, V.A. Localization of yeast telomeres to the nuclear periphery
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| is separable from transcriptional repression and telomere stability
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| functions. ‘‘‘Mol Cell ‘‘‘2001; 8(1): 189-199. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11511372&dopt=Abstract Abstract]
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| | |
| *Hood, J.K., Hwang, W.W., and Silver, P.A. The Saccharomyces
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| cerevisiae cyclin Clb2p is targeted to multiple subcellular locations
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| by cis- and trans-acting determinants. ‘‘‘J. Cell Sci. ‘‘‘2001;
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| 114 (3): 589-597. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11171327&dopt=Abstract Abstract]
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| | |
| *Brodsky, A.S. and Silver, P.A. Pre-mRNA processing factors
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| are required for nuclear export. ‘‘‘RNA’’’ 2000; 6(12): 1737-1749.<A
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| HREF="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11142374&dopt=Abstract Abstract]
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| | |
| *Colas, P., Cohen, B., Ferrigno, P.K., Silver, P.A., and Brent,
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| R. Targeted modification and transportation of cellular proteins.
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| ‘‘‘Proc.Natl.Acad.Sci. USA ‘‘‘2000 Dec 5; 97(25): 13720-13725.
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| [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11106396&dopt=Abstract Abstract]
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| *Weiss, V. H., McBride, A. E., Kim, H. K., Hogle, J. M., and
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| Silver, P. A. The structure and oligomerization of the yeast
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| arginine methyltransferase, Hmt1. ‘‘‘Nat. Struct. Biol.’’’ 2000;
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| 7: 1165-1171. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11101900&dopt=Abstract Abstract]
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| | |
| *Stage-Zimmermann, T., Schmidt, U. and Silver, P.A. Factors
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| Affecting Nuclear Export of the 60S Ribosomal Subunit In Vivo.
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| ‘‘‘Mol Biol Cell ‘‘‘2000 Nov;11(11):3777-3789. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11071906&dopt=Abstract Abstract]
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| *Krebber, H. and Silver, P.A. Directing proteins to nucleus
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| by fusion to nuclear localization signal tags. ‘‘‘Methods Enzymol’’’
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| 2000;327:283-96. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11044991&dopt=Abstract Abstract]
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| | |
| *Prinz, W.A., Grzyb, L., Veenhuis, M., Kahana, J.A., Silver,
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| P.A. and Rapoport, T.A. Mutants affecting the structure of the
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| cortical endoplasmic reticulum in Saccharomyces cerevisiae. ‘‘‘J
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| Cell Biol ‘‘‘2000 Aug 7;150(3):461-74. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10931860&dopt=Abstract Abstract]
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| | |
| *Hood, J.K. and Silver, P.A. Diverse nuclear transport pathways
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| regulate cell proliferation and oncogenesis.’’’ Biochim Biophys
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| Acta’’’ 2000 Jul 31;1471(1):M31-41. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10967423&dopt=Abstract Abstract]
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| *Shen, E.C., Stage-Zimmermann, T., Chui, P., and Silver, P.A.
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| The yeast mRNA binding protein Npl3p interacts with the Cap Binding
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| Complex. ‘‘‘J. Biol. Chem.’’’ 2000 May 22. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10823828&dopt=Abstract Abstract]
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| *Ferrigno, P. and Silver, P.A. Polyglutamine expansions: proteolysis,
| |
| chaperones, and the dangers of promiscuity. ‘‘‘Neuron’’’ 2000
| |
| Apr;26(1):9-12. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10798387&dopt=Abstract Abstract]
| |
| | |
| *Hood, J.K., Casolari, J.M., and Silver, P.A. Nup2p is located
| |
| on the nuclear side of the nuclear pore complex and coordinates
| |
| Srp1p/importin-alpha export. ‘‘‘J. Cell Sci.’’’ 2000 Apr;113
| |
| (Pt 8):1471-80. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10725229&dopt=Abstract Abstract]
| |
| | |
| *Jones, A.L., Quimby, B.B., Hood, J.K., Ferrigno, P., Keshava,
| |
| P.H., Silver, P.A., and Corbett, A.H. SAC3 may link nuclear protein
| |
| export to cell cycle progression. ‘‘‘Proc. Natl. Acad. Sci. USA’’’
| |
| 2000 Mar 28;97(7):3224-9. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10716708&dopt=Abstract Abstract]
| |
| | |
| *McBride, A.E., Weiss, V.H., Kim, H.K., Hogle, J.M., and Silver,
| |
| P.A. Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p
| |
| and its in vivo function. Cofactor binding and substrate interactions.
| |
| ‘‘‘J. Biol. Chem. ‘‘‘2000 Feb 4;275(5):3128-36. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10652296&dopt=Abstract Abstract]
| |
| | |
| *Damelin, M. and Silver, P.A. Mapping interactions between
| |
| nuclear transport factors in living cells reveals pathways through
| |
| the nuclear pore complex. ‘‘‘Mol. Cell ‘‘‘2000; 5: 133-140.
| |
| [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10678175&dopt=Abstract Abstract]
| |
| | |
| *Morehouse, H., Buratowski, R.M., Silver, P.A., and Buratowski,
| |
| S. The importin/karyopherin kap114 mediates the nuclear import
| |
| of TATA-binding protein. ‘‘‘Proc. Natl. Acad. Sci. U.S.A.’’’
| |
| 1999; 96(22):12542-7.
| |
| | |
| *Ferrigno, P. and Silver, P.A. Regulated nuclear localization
| |
| of stress-responsive factors: how the nuclear trafficking of
| |
| protein kinases and transcription factors contributes to cell
| |
| survival. ‘‘‘Oncogene’’’ 1999; 18(45):6129-34.
| |
| | |
| *Moy, T.I. and Silver, P.A. Nuclear export of the small ribosomal
| |
| subunit requires the ran-GTPase cycle and certain nucleoporins.
| |
| ‘‘‘Genes & Dev. ‘‘‘1999; 13(16):2118-33.
| |
| | |
| *Krebber, H., Taura, T., Lee, M.S., and Silver, P.A. Uncoupling
| |
| of the hnRNP Npl3p from mRNAs during the stress-induced block
| |
| in mRNA export. ‘‘‘Genes & Dev.’’’ 1999;13(15):1994-2004.
| |
| | |
| *Brodsky, A.S. and Silver, P.A. Nuclear transport HEATs up.
| |
| ‘‘‘Nat. Cell. Biol.’’’ 1999;1(3):E66-E67.
| |
| | |
| *Zeng, X., Kahana, J.A., Silver, P.A., Morphew, M.K. McIntosh,J.R.,Fitch,
| |
| I.T., Carbon, J., and Saunders, W.S. Slk19p is a centromere protein
| |
| that functions to stabilize mitotic spindles. ‘‘‘J. Cell. Biol.’’’
| |
| | |
| 1999;146(2):415-25.
| |
| | |
| *Defossez, P.A., Prusty, R., Kaeberlein, M., Lin, S.J., Ferrigno,
| |
| P., Silver, P.A., Keil, R.L., and Guarente, L. Elimination of
| |
| replication block protein Fob1 extends the life span of yeast
| |
| mother cells. ‘‘‘Mol. Cell ‘‘‘1999; 3(4):447-55.
| |
| | |
| *Hood, J.K. and Silver, P.A. In or out? Regulating nuclear
| |
| transport. ‘‘‘Curr. Opin. Cell. Biol. ‘‘‘1999;11(2):241-7.
| |
| | |
| *Valentini, S.R., Weiss, V.H., and Silver, P.A. Arginine methylation
| |
| and binding of Hrp1p to the efficiency element for mRNA 3'-end
| |
| formation. ‘‘‘RNA’’’ 1999; 5(2):272-80.
| |
| | |
| *Ferrigno, P. and Silver, P.A. Analysis of nuclear transport
| |
| in vivo. ‘‘‘Meth. Cell Biol. ‘‘‘1999;58:107-22.
| |
| | |
| *Seedorf, M., Damelin, M., Kahana, J.A., Taura, T., and Silver,
| |
| P.A. Interactions between a nuclear transporter and a subset
| |
| of nuclear pore complex proteins depend on Ran GTPase. ‘‘‘Mol.
| |
| Cell. Biol. ‘‘‘1999;19(2):1547-57.
| |
| | |
| *Hood, J.K. and Silver, P.A. Cse1p is required for export of
| |
| Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae.
| |
| ‘‘‘J. Biol. Chem. ‘‘‘1998; 273(52):35142-6.
| |
| | |
| *Silberstein, S., Schlenstedt, G., Silver, P.A., and Gilmore,
| |
| R. A role for the DnaJ homologue Scj1p in protein folding in
| |
| the yeast endoplasmic reticulum. ‘‘‘J. Cell. Biol.’’’ 1998;143(4):921-33.
| |
| | |
| *Ferrigno, P., Posas, F., Koepp, D., Saito, H., and Silver,
| |
| P.A. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires
| |
| the importin beta homologs NMD5 and XPO1. ‘‘‘EMBO J.’’’ 1998;17(19):5606-14.
| |
| | |
| *Finley et al., Unified nomenclature for subunits of the yeast
| |
| proteasome regulatory particle. ‘‘‘TIBS ‘‘‘1998; 23:244-245.
| |
| | |
| *Taura, T., Krebber, H. and Silver, P.A. A member of the Ran
| |
| binding protein family, Yrb2p, is involved in NES dependent nuclear
| |
| protein export. ‘‘‘Proc. Natl. Acad. Sci. USA ‘‘‘1998; 95:7427-7432.
| |
| | |
| *Shen, E.C., Henry, M.F., Weiss, V.H., Valentini, S., Silver,
| |
| P.A., and Lee, M.S. Arginine methylation facilitates the nuclear
| |
| export of hnRNPs. ‘‘‘Genes & Dev. ‘‘‘1998; 12:679-691.
| |
| | |
| *Webb, C.D., Graumann, P., Kahana, J.A., Teleman, A., Silver,
| |
| P.A. and Losick, R. Use of time-lapse microscopy to visualize
| |
| rapid movement of the replication origin region of the chromosome
| |
| during the cell cycle in Bacillus subtilis. ‘‘‘Mol. Microbiol.
| |
| ‘‘‘1998; 28:883-892.
| |
| | |
| *Kahana, J.A., Schlenstedt, G., Geiser, J.R., Evanchuck, D.M.,
| |
| Hoyt, A. and Silver, P.A. The yeast dynactin complex is involved
| |
| in partitioning the mitotic spindle between mother and daughter
| |
| cells during anaphase B. ‘‘‘Mol. Biol. Cell ‘‘‘1998; 9:1741-1756.
| |
| | |
| *Huyett, A., Kahana, J., Silver, P., Zeng, X., and Saunders,
| |
| W.S. Microtubule density controlled by antagonistic kinesin motors.
| |
| ‘‘‘J. Cell Sci. ‘‘‘1998; 111:295-301.
| |
| | |
| *Vodicka, M.A., Koepp, D.M., Silver, P.A. and Emerman, M. HIV-1
| |
| Vpr interacts with the nuclear transport pathway to promote macrophage
| |
| infection. ‘‘‘Genes & Dev. ‘‘‘1998; 12:175-185.
| |
| | |
| *Kahana, J. and Silver, P.A. The uses of GFP in yeast. in ‘‘‘GFP:
| |
| Green Fluorescent Protein Strategies and Applications, ‘‘‘ed.
| |
| by M. Chalfie and S. Kain; John Wiley & Sons, Inc. 1998, in press.
| |
| | |
| *Scott, H.S., Antonarakis, S.E., Lalioti, M.D., Rossier, C.,
| |
| Silver, P.A., and Henry, M.F. Identification and characterization
| |
| of two putative human arginine methyltransferases (HRMT1L1 and
| |
| HRMT1L2). ‘‘‘Genomics ‘‘‘1998; 15:330-340.
| |
| | |
| *Koepp, D. and Silver, P.A. Nucleo-cytplasmic transport and
| |
| cell proliferation. ‘‘‘BBA Reviews in Cancer ‘‘‘1998; 1377:39-47.
| |
| | |
| *Taura, T., Schlenstedt, G. and Silver, P.A. Yrb2 is a nuclear
| |
| protein that interacts with Prp20p, a yeast Rcc1 homologue. ‘‘‘J.
| |
| Biol. Chem. ‘‘‘1997; 272:31877.
| |
| | |
| *Kessler, Henry, M., Shen, E., Zhao, J., Gross, S., Silver,
| |
| P., and Moore, C.L. Hrp1, an RNA binding protein that shuttles
| |
| between the nucleus and cytoplasm, is required for mRNA 3' end
| |
| formation in yeast. ‘‘‘Genes & Dev. ‘‘‘1997; 11:2545-2556.
| |
| | |
| *Lithgow, T., Cuezva, J.M., and Silver, P.A. Highways for delivery
| |
| to the mitochondria. ‘‘‘Trends in Biochemical Sciences ‘‘‘1997;
| |
| 110-113.
| |
| | |
| *Corbett, A.H., Koepp, D.M., and Silver, P.A. Indirect immunofluorescence
| |
| in Saccharomyces cerevisiae. in ‘‘‘Cell Biology: a Laboratory
| |
| Manual ‘‘‘ed. by David Spector; Cold Spring Harbor Press, 1997.
| |
| | |
| *Silver, P.A. Scj1p. in ‘‘‘Guidebook to Molecular Chaperones
| |
| and Protein Folding Catalysts, ‘‘‘ed. by M.-J. Gething; Sambrook
| |
| & Tooze at Oxford University Press, 1997.
| |
| | |
| *Corbett, A. and Silver, P. Genetic analysis of nuclear transport.
| |
| ‘‘‘Microbiology and Molecular Biology Reviews ‘‘‘1997; 61:193-211.
| |
| | |
| *Lee, M. and Silver, P.A. RNA movement from the nucleus. ‘‘‘Current
| |
| Opinion in Genetics & Development ‘‘‘1997; 212-219.
| |
| | |
| *Seedorf, M. and Silver, P. A. Importin/Karyopherin protein
| |
| family members required for mRNA export from the nucleus. ‘‘‘Proc.
| |
| Natl. Acad. Sci. USA ‘‘‘1997; 94:8590-8595.
| |
| | |
| *Clarkson, W.D., Corbett, A.H., Paschal, B.M., Kent, H.K.,
| |
| McCoy, A.J., Gerace, l., Silver, P.A., Stewart, M. Nuclear protein
| |
| import is descreased by engineered mutants of nuclear transport
| |
| factor 2 (NTF2) that do not bind GDP-Ran. ‘‘‘J. Mol. Biol. ‘‘‘1997;
| |
| 272:716-730.
| |
| | |
| *Campbell, K.S., Mullane, K., Aksoy, I., Pipas, J.M., Silver,
| |
| P.A., Roberts, T.M., Schaffhausen, B.S., and DeCaprio, J.A. The
| |
| J-domain of SV40 large TAg mediates Hsc70 binding and viral DNA
| |
| replication. ‘‘‘Genes & Dev. ‘‘‘1997; 11:1098-1110.
| |
| | |
| *Wong, D.H., Corbett, A.H., Kent, H., Stewart, M. and Silver,
| |
| P.A. Interaction between the small GTPase Ran/Gsp1 and Ntf2 is
| |
| required for nuclear import. ‘‘‘Mol. Cell Biol. ‘‘‘1997; 17:3755-3767.
| |
| | |
| *Kahana, J. and Silver, P. Use of the A. victoria green fluorescent
| |
| protein to study protein dynamics in vivo. ‘‘‘Current Protocols
| |
| in Molecular Biology ‘‘‘1996; 9.7.22-9.7.28.
| |
| | |
| *Koepp, D. and Silver, P. A GTPase that controls nuclear trafficking:
| |
| Running the right way or walking RANdomly? ‘‘‘Cell ‘‘‘1996;
| |
| 87:1-20.
| |
| | |
| *Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D.,
| |
| Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E.,
| |
| Taura, T. and Silver, P. Genetic analysis of macromolecular transport
| |
| across the nuclear envelope. (Proceedings from the Nobel Symposium)
| |
| ‘‘‘Exp. Cell Res. ‘‘‘1996; 229:212-216.
| |
| | |
| *Koepp, D.M., Wong, D.H., Corbett, A.H., and Silver, P.A. Dynamic
| |
| localization of the nuclear import receptor and its interactions
| |
| with transport factors. ‘‘‘J. Cell Biol. ‘‘‘1996; 6:1163-1176.
| |
| | |
| *DeHoratius, C. and Silver, P.A. Nuclear transport defects
| |
| and nuclear envelope alterations are associated with mutation
| |
| of the Saccharomyces cerevisiae NPL4 gene. ‘‘‘Mol. Biol. Cell
| |
| ‘‘‘1996; 7:1835-1855.
| |
| | |
| *Henry, M. and Silver, P. A novel arginine methyltransferase
| |
| (HMT1) modifies a poly(A) RNA-binding protein. ‘‘‘Mol. Cell.
| |
| Biol. ‘‘‘1996; 16:3668-3678.
| |
| | |
| *Haarer, K., Corbett, A.H., Kweon, Y., Petzold, A.S., Silver,
| |
| P.A. and Brown, S.S. SEC3 mutations are synthetically lethal
| |
| with profilin mutations and cause defects in diploid-specific
| |
| bud-site selection. ‘‘‘Genetics ‘‘‘1996; 144:495-510.
| |
| | |
| *Corbett, A.H. and Silver, P. A. The NTF2 gene encodes an essential
| |
| highly conserved protein that functions in nuclear transport
| |
| in vivo. ‘‘‘J. Biol. Chem. ‘‘‘1996; 271:18477-18484.
| |
| | |
| *Lee, M., Henry, M., and Silver, P. A protein that shuttles
| |
| between the nucleus and the cytoplasm is an important mediator
| |
| of RNA export. ‘‘‘Genes & Dev. ‘‘‘1996; 10:1233-1246.
| |
| | |
| *Henry, M., Borland, C., Bossie, M. and Silver, P. Potential
| |
| RNA binding proteins in Saccharomyces cerevisiae identified as
| |
| suppressors of temperature-sensitive mutations in NPL3. ‘‘‘Genetics
| |
| ‘‘‘1996; 142:103-115.
| |
| | |
| *Koepp, D.M. and Silver, P. Rna1p, a GTPase activating protein,
| |
| plays a direct role in nuclear transport. ‘‘‘J. NIH Research
| |
| ‘‘‘1995; 7:53-54.
| |
| | |
| *Schlenstedt, G., Wong, D., Koepp, D. and Silver, P. Mutants
| |
| in a yeast Ran binding protein are defective in nuclear transport.
| |
| ‘‘‘EMBO J. ‘‘‘1995; 21:5367-5378.
| |
| | |
| *Corbett, A., Koepp, D., Schlenstedt, G., Lee, M., Hopper,
| |
| A., and Silver, P. Rna1p, a Ran/TC4 GTP-activating protein, is
| |
| required for nuclear import. ‘‘‘J. Cell Biol. ‘‘‘1995; 130:1-10.
| |
| | |
| *Kahana, J., Schnapp, B. and Silver, P. Kinetics of spindle
| |
| pole body separation in budding yeast. ‘‘‘Proc. Natl. Acad. Sci.
| |
| USA ‘‘‘1995; 92:9707-9711.
| |
| | |
| *Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D.,
| |
| Silver, P.A. and Fink, G.R. A yeast nuclear import receptor homologue
| |
| required for mitosis. ‘‘‘Proc. Natl. Acad. Sci. USA ‘‘‘1995;
| |
| 92:7647-7651.
| |
| | |
| *Schlenstedt, G., Harris, S., Risse, B., Lill, R. and Silver,
| |
| P. A yeast DnaJ homologue, Scj1, can function in the endoplasmic
| |
| reticulum with BiP/Kar2p via a conserved domain that specifies
| |
| interaction with Hsp70s. ‘‘‘J. Cell Biol. ‘‘‘1995; 129:979-988.
| |
| | |
| *Schlenstedt, G., Saavedra, C., Loeb, J., Cole, C. and Silver,
| |
| P. The GTP-bound form of the yeast Ran/TC4 homologue blocks bi-directional
| |
| transport across the nuclear envelope. ‘‘‘Proc. Natl. Acad. Sci.
| |
| USA ‘‘‘1995; 92:225-229.
| |
| | |
| *Flach, J., Bossie, M., Vogel, J., Corbett, A., Jinks, T.,
| |
| Willins, D., and Silver, P.A. A yeast RNA binding protein shuttles
| |
| between the nucleus and the cytoplasm. ‘‘‘Mol. Cell Biol. ‘‘‘1994;
| |
| 14:8399-407.
| |
| | |
| *Osborne, M. A., Schlenstedt, G. Jinks, T. and Silver, P. Nuf2,
| |
| a spindle pole body associated protein required for nuclear division
| |
| in yeast. ‘‘‘J. Cell Biology ‘‘‘1994; 125:853-66.
| |
| | |
| *Osborne, M. and Silver, P. Nucleocytoplasmic transport in
| |
| the yeast Saccharomyces cerevisiae. ‘‘‘Annual Review of Biochemistry
| |
| ‘‘‘1993; 62:219-54.
| |
| | |
| *Silver, P. and Way, J. Eukarytotic DnaJ homologues and the
| |
| specificity of hsp70 action. ‘‘‘Cell ‘‘‘1993; 74:1-3.
| |
| | |
| *Schlenstedt, G. , Hurt, E., Doye, V. and Silver, P. Reconstitution
| |
| of nuclear protein transport with semi-intact yeast cells. ‘‘‘J.
| |
| Cell Biology ‘‘‘1993; 123:785-98.
| |
| | |
| *Kurihara, T. and Silver, P. Suppression of a sec63 mutation
| |
| identifies a novel component of the ER translocation apparatus.
| |
| ‘‘‘Mol. Biol. Cell ‘‘‘1993; 4:919-30.
| |
| | |
| *Nelson, M., Kurihara, T. and Silver, P. Extragenic suppressors
| |
| of mutations in the cytoplasmic C-terminus of Sec63 define five
| |
| genes in S. cerevisiae. ‘‘‘Genetics ‘‘‘1993; 134:159-73.
| |
| | |
| *Stochaj, U., Bossie, M., van Zee, K. and Silver, P. Analysis
| |
| of conserved binding proteins for nuclear localization sequences.
| |
| ‘‘‘J. Cell Science ‘‘‘1993; 104:89-95.
| |
| | |
| *Kurihara, T. and Silver, P. DnaJ homologs and protein transport.
| |
| in ‘‘‘Membrane Biogenesis and Protein Targeting, ‘‘‘ed. W. Neupert
| |
| and R. Lill; Elsevier Science Publishers, 1992; 309-27.
| |
| | |
| *Bossie, M., Barcelo, G., Dehoratius, C., and Silver, P. A
| |
| mutant nuclear protein with similarity to RNA binding proteins
| |
| interferes with nuclear import in yeast. ‘‘‘Mol. Biol. Cell ‘‘‘1992;
| |
| 3:875-93.
| |
| | |
| *Stochaj, U. and Silver, P. A conserved phosphoprotein that
| |
| specfically binds nuclear localization sequences is involved
| |
| in nuclear import. ‘‘‘J. Cell Biology ‘‘‘1992; 117:473-82.
| |
| | |
| *Silver, P. How proteins enter the nucleus. ‘‘‘Cell ‘‘‘1991;
| |
| 64:489-97.
| |
| | |
| *Blumberg, H. and Silver, P. A yeast protein containing two
| |
| separated zinc fingers is required for normal cell growth. ‘‘‘Gene
| |
| ‘‘‘1991; 107:101-10.
| |
| | |
| *Stochaj, U., Osborne, M., Kurihara, T. and Silver, P. A yeast
| |
| protein that binds nuclear localization sequences: Purification,
| |
| localization and antibody inhibition of binding activity. ‘‘‘J.
| |
| Cell Biology ‘‘‘1991; 113:1243-54.
| |
| | |
| *Blumberg, H. and Silver, P. SCJ1, a DNAJ homologue that alters
| |
| protein sorting in yeast. ‘‘‘Nature ‘‘‘1991; 349:627-30.
| |