Silver: Publications (By subject)

THIS PAGE IS A WORK IN PROGRESS - NOT A COMPLETE LIST YET

Synthetic Biology and Bioengineering

• Mattozzi M, Ziesack M, Voges MJ, Silver PA, Way JC. Expression of the sub-pathways of the Chloroflexus aurantiacus 3-hydroxypropionate carbon fixation bicycle in E. coli: Toward horizontal transfer of autotrophic growth. 2013. Metabolic Eng., accepted for publication.

• Ford TJ and Silver PA. Rephrasing the biofuel question. 2013. Microbe, in press.

• Ducat DC, Avelar-Rivas JA, Way JC and Silver PA. Re-routing carbon-flux to enhance photosynthetic productivity. 2012. App & Env Eng., 2012 Apr;78(8):2660-.

• Burrill DR, Inniss MC, Boyle PM and Silver PA. Synthetic memory circuits for tracking human cell fate. 2012. Genes & Dev., 26:1486-1497.

• Haynes K, Ceroni F, Flicker D, Younger A and Silver PA. A sensitive switch for visualizing natural gene silencing in single cells. 2012. ACS Synthetic Biology, Mar 16;1(3):99-106.

• Lohmueller J, Armel T, and Silver PA. A tunable zinc finger-based framework for Boolean logic computation in mammalian cells. 2012, Nuc Acids Res., Jun;40(11):5180-7. doi: 10.1093/nar/gks142. Epub 2012 Feb 9.

• Silver PA, Haynes K, Weiss R. Synthetic meets cell biology. Mol Biol Cell. 2012 Mar;23(6):967.

• Garg A, Lohmueller J, Silver PA and Armel T. Engineering synthetic TAL effectors with orthogonal target sites. 2012. Nuc Acids Res, Aug;40(15):7584-95. doi: 10.1093/nar/gks404. Epub 2012 May 11.

• Nishida K and Silver PA. Induction of Biogenic Magnetization and Redox Control by a Component of the Target of Rapamycin Complex 1 Signaling Pathway. PLoS Biology. 2012. [[1]. Press Release

• Agapakis CM, Boyle PM and Silver PA. Natural strategies for the spatial optimization of metabolism in synthetic biology. 2012. Nature Chem Biol., May 17;8(6):527-35.

• Ducat D and Silver PA. Improving carbon fixation pathways. 2012. Curr Op in Chem Biol., Aug;16(3-4):337-44. doi: 10.1016/j.cbpa.2012.05.002. Epub 2012 May 29.

• Chen A and Silver PA. Designing biological compartmentalization. 2012. Trends in Cell Biol., Dec;22(12):662-70. doi: 10.1016/j.tcb.2012.07.002. Epub 2012 Jul 27.

• Delebeque C, Silver PA, and Lindner A. Assembling proteins in vivo on designed RNA scaffolds. 2012. Nature Protocols, Oct;7(10):1797-807. doi: 10.1038/nprot.2012.102. Epub 2012 Sep 6.

• Chen AH, Afonso D, Savage D and Silver PA. Spatial and Temporal Organization of Chromosome Duplication and Segregation in the Cyanobacterium Synechococcus elongatus PCC 7942. PLoS One. 2012;7(10):e47837. doi: 10.1371/journal.pone.0047837. Epub 2012 Oct 242012.

• PLoS Collection in Synthetic Biology [2]

• Silver PA. Designing biological systems to report on disease. 2012. Designing Biological Systems to Report on Disease. Cancer Research. December 13, 2012 72:IA4; doi:10.1158/1538-7445.CSB12-IA4

• Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd J, Gedeon MA, Quinn J, Paull ML, Raman AM, Theilman MR, Wang L, Winn JG, Medvedik O, Schellenberg, K,Haynes KA, Viel A, Brenner TJ, Church GM, Shah JV and Silver PA. A Biobrick compatible Strategy for genetic modification of plants. 2012. J Biol Eng., Jun 20;6(1):8. doi: 10.1186/1754-1611-6-8.

• Bonacci W, Teng PK, Afonso B, Niederholtmeyer H, Grob P, Silver PA and Savage DF. Modularity of a carbon-fixing organelle. 2011. Proc Natl Acad Sci., in press.

• Delebecque CJ, Lindner AB, Silver PA, and Aldaye FA. Organization of intracellular reactions with rationally designed RNA assemblies. Science, 2011. 333:470-4. (published online in ScienceExpress June 23, 2011.

• Haynes KA, Silver P. Synthetic reversal of epigenetic silencing. J Biol Chem. 2011 Jun 12. [Epub ahead of print]

• Ducat D, Sachdeva G and Silver PA. Rewiring Hydrogenase-dependent Redox Circuits in Cyanobacteria. 2011. Proc Natl Acad Sci, 108:3941-6.

• Ducat D, Way J, and Silver PA. Engineering Cyanobacteria to Generate High-Value Products. 2011. Trends in Biotechnology, Feb;29(2):95-103. Epub 2011 Jan 5.

• Burrill D and Silver PA. Synthetic circuit identifies sub-populations with sustained memory of DNA damage. 2011. Genes & Dev., 25:434-9.

• Smolke CD and Silver PA. Informing biological design by integration of systems and synthetic biology. 2011. Cell, 144:855-9.

• Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC and Silver PA. 2011. Towards a synthetic chloroplast. PLoS One, Apr 20;6(4):e18877.

• Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA and Wintermute EH. A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism. 2011. J Biol Eng. May 26;5(1):7. [Epub ahead of print].

• Burrill D and Silver PA. Recording cellular experience of DNA damage. 2011. Cell Cycle, Aug 1;10(15).[Epub ahead of print]in press.

• Way JC, Silver PA and Howard RJ. Sun-driven microbial synthesis of chemicals in space. 2011. International Journal of Astrobiology. In press.

• Burrill DR, Boyle PM, and Silver p1. 2011. A new approach to an old problem: Synthetic biology tools for human disease & metabolism. Cold Spring Harbor 76th Symposium on Quantitative Biology.

• Kennedy, CJ, Boyle, PM, Waks, Z, and Silver, PA Systems-level engineering of non-fermentation metabolism in yeast. 2009. Genetics, in press.

• Waks, Z. and Silver, PA. Engineering a synthetic dual organism system for hydrogen production. 2009. Applied and Environmental Microbiology. 75:1867-75.

• Savage, DF, Way, J and Silver, PA. Defossilling fuel: how synthetic biology can transform biofuel production. 2008. ACS Chem. Biol. 3:13-6.

• Cironi, P, Swinburne, IA, and Silver, PA. Enhancement of cell-type specificity by quantitative modulation of a chimeric ligand. 2008. J. Biol Chem.

• Drubin, DA, Way, JC, and Silver, PA. Designing Biological Systems. 2007. Genes and Development, 21:242-54

• Ajo-Franklin, CM, Drubin, DA, Eskin, J., Gee, E., Landgraf, D., Philips, I. and Silver, PA. Rational design of memory in eukaryotic cells. 2007. Genes and Development, 2271-6.

• Zhou, Z.*, Cironi, P.*, Lin, AJ.*, Xu, Y., Hrvatin, S., Golan, DE., Silver, PA., Walsh, CT., Yin, J. Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases. 2007. ACS Chemical Biology, 2:337-346. (* These authors contribute equally)

• Phillips I, Silver P, A New Biobrick Assembly Strategy Designed for Facile Protein Engineering, MIT Synthetic Biology Working Group Reports, published online 20 April 2006 at MIT dspace (doi: 1721.1/32535)

• Drubin, DA., Garakani, AM., and Silver, PA. Motion as phenotype. The use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics. 2006. BMC Cell Biology, 7:19. Abstract.

• Hitchcock, A.L., Kahana, J.A., and Silver, P.A. The uses of green fluorescent protein in yeasts. 2006. Methods Biochem Anal. 47:179-201

• Brodsky, A.S. and Silver, P.A. A microbead-based system for identifying and characterizing RNA-protein interactions by flow cytometry. Mol Cell Proteomics 2002; 1(12): 922-9. Abstract

• Devroe, E. and Silver, P.A. Retrovirus-delivered siRNA. BMC Biotechnol. 2002; 2(1): 15. Abstract

• Krebber, H. and Silver, P.A. Directing proteins to nucleus by fusion to nuclear localization signal tags. Methods Enzymol 2000;327:283-96. Abstract

• Colas, P., Cohen, B., Ferrigno, P.K., Silver, P.A., and Brent, R. Targeted modification and transportation of cellular proteins. Proc.Natl.Acad.Sci. USA 2000 Dec 5; 97(25): 13720-13725.

Systems Biology

• Lee, S., Dudley, AM, Drubin, D., Silver, PA, Krogan, N., Pe'er, D., and Koller, D. Learning a Prior on Regulatory Potential from eQTL data. 2009, PLos Genetics, in press.

• Way, J. and Silver, PA. Molecular systems biology in drug development. 2007. Clinical Pharmacology and Therapeutics, in press.

• Komili, S., Farny, NG, Roth, FP and Silver, PA. Functional specificity among ribosomal proteins regulates gene expression. 2007. Cell 131:557-71.

• McKee, AE and Silver, PA. 2007. Systems perspective on mRNA processing. 2007. Cell Research, 7:581-90.

• Way, J. and Silver, PA. Systems engineering without an engineer: Why we need systems biology. 2007, Complexity, 13:22-29.

• Komili, S. and Silver, PA. Coupling of gene expression mechanisms - insights from global studiess. 2007. Nature Reviews in Genetics. In press.

• Moore, M. and Silver, PA. Global analysis of mRNA splicing. 2007. RNA, in press.

• Moore, M., Schwartzfarb, EM, Silver, PA and Yu, MC. Differential recruitment of the splicing machinery during transcription predicts genome-wide patterns of mRNA splicing. 2006. Molecular Cell, 24:903-915.

• Tsankov, A., Brown, C., Yu, M., Win, M., Silver, PA. and Casolari, J. Communication between levels of transcriptional organization improve robustness and adaptivity. 2006, Molecular Systems Biology, 2:65 (featured article)

Genome Organization and Dynamics

• Brown, CR, Kennedy, CJ, Delmar, VA, Forbes, DJ, and Silver, PA. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. 2008. Genes and Dev., in press.

• Brown, CR and Silver, PA. Transcriptional regulation at the nuclear pore complex. 2007. Curr. Opin Genet Dev. 2:100-6.

• Yu, MC, Lamming, DW, Eskin, JA, Sinclair, DA, and Silver, PA. The role of protein arginine methylation in formation of silent chromatin. 2006, Genes and Development, 20:3249-5

• Auld, KL., Brown, CR., Casolari, JM., Komili, S. and Silver, PA. Genomic Association of the Proteasome Demonstrates Overlapping Gene Regulatory Activity with Transcription Factor Substrates. 2006. Molecular Cell, 21:861-871. Absract.

• Carroll, JS, Meyer, CA, Song, J., Li, W., Geistlinger, TR, Eeckhoute, J., Brodsky, A., Krasnickas, K., Fertuck, KC, Hall, G., Wang, Q., Bekiranov, S., Sementchenko, V., Fox, EF., Silver, PA, Gingeras, T., Liu, XS, and Brown, M. Genome-wide analysis of estrogen receptor binding sites. 2006. Nature Genetics, 38:1289-97.

• Casolari, J.M., Brown, C.R., Drubin, D.A., Rando, O.J., and Silver, P.A. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes Dev. 2005. May 15;19(10):1188-98.

• Carrol, J.S., Liu, X.S., C.R., Brodsky, A.S., Meyer, C.A., Li, W., Szary, A., Shao, W., Hesterman, E., Geistlinger, T.R., Fox, E.A., Silver, P.A., and Brown, M. Chromosome-wide mapping of estrogen receptor binding reveals long-range combinatorial regulation requiring forkhead proteins. Cell. 2005. July 15;122(1):33-43

• Casolari, J.M., Brown, C.R., Drubin, D.A., Rando, O.J., and Silver, P.A. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes Dev. 2005. May 15;19(10):1188-98.

• Brodsky, A.S., Meyer, C.A., Hall, G., Swinburne, I.A., Keenan, B.J., Liu, X.S., Fox, E.A., and., Silver, P.A. Genomic mapping of RNA Polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biology. 2005. Jul 15:6(8): R64 Abstract

• Damelin, M., Simon, I., Moy, T.I., Wilson, B., Komili, S., Tempst, P., Roth, F.P., Young, R.A., Carins, B.R., and Silver, P.A. The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Mol Cell 2002; 9 (3): 563-73.

RNA and Ribosome Dynamics

• Hurt, J., Farny, N. and Silver, PA. A conserved CCCH-zinc finger type protein regulates mRNA nuclear adenylation and export. 2009. J. Cell Biol., 185:279-290.

• Farny, NG, Hurt, JA and Silver, PA. Definition of global and transcript-specific mRNA export pathways in metazoans. 2008. Genes & Dev., in press.

• Moore, M. and Silver, PA. Global analysis of mRNA splicing. 2007. RNA, in press.

• McKee, AE and Silver, PA. 2007. Systems perspective on mRNA processing. 2007. Cell Research, 7:581-90.

• McKee, A., Neretti, N., Carvalho, LE, Meyer, CA, Fox, EA, Brodsky, AS, and Silver, PA, Exon expression profiling reveals stimulus-mediated exon use in neural cells. 2007. Genome Biology, in R15.

• Moore, M., Schwartzfarb, EM, Silver, PA and Yu, MC. Differential recruitment of the splicing machinery during transcription predicts genome-wide patterns of mRNA splicing. 2006. Molecular Cell, 24:903-915.

• Swinburne, IA., Meyer, CA., Liu, S., Silver, PA, and Brodsky, AS. Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription, 2006. Genome Research, Abstract.

• Gama-Carva;ho, M., Barbosa-Morais, N., Brodsky, A., Silver, PA and Carmo-Fonesca, M. Genome wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. 2006. Genome Biology, in press

• Bachand, F., Lackner, D., Bahler, J., and Silver, PA. Autoregulation of ribosome bio-synthesis by a translational response in fission yeast. 2006. Mol Cell Biol., 26:1731-42. Absract

• McKee, A.E., Minet, E., Stern, C., Riahi, S., Stiles, C.D., and., Silver, P.A. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005. July 20;5(1):14

• Hieronymus, H., Yu, M.C., and Silver, P.A. Genome-wide mRNA surveillance is coupled to the mRNA export. Genes Dev. 2004. Nov 1; 18(21):2652-62.Abstract

• Yu, M.C., Bachand F., McBride, A.E., Komili, S., Casolari, J.M., and Silver, P.A. Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes Dev 2004, Aug. 15. 18(16):2024-35. Abstract
• McKee A.E.. and Silver, P.A. REF-ereeing the cytoplasmic fate of mRNA via nuclear export. Dev Cell 2004. July 7; 23(13):2641-50.Abstract
• Bachand, F. and Silver, P.A. PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits. EMBO J 2004. July 7; 23(13):2641-50.Abstract
• Hieronymus, H. and Silver, P.A. Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery. Nat. Genet. 2003; 33(2):155-61. Abstract
• Lei, E.P., Stern, C.A., Fahrenkrog, B., Krebber, H., Moy, T.I., Aebi, U. and Silver, P.A., Sac3 is an mRNA export factor that localizes to the cytoplasmic fibrils of the nuclear pore complex. Mol Biol Cell 2002; In Press.
• Lei, E. P. and Silver, P.A. Intron status and 3'-end formation control cotranscriptional export of mRNA. Genes Dev 2002; 16: 2761-2766. Abstract
• Moy, T.I., and Silver, P.A. Requirements for the nuclear export of the small ribosomal subunit. J Cell Sci 2002; 115 (Pt 14): 2985-95.Abstract
• Lei, E.P. and Silver, P.A. Protein and RNA export from the nucleus. Dev Cell. 2002; 2 (3): 261-72. Abstract
• Valentini, S.R., Casolari, J.M., Oliveira, C.C., Silver, P.A. and McBride, A.E. Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 2002; 160 (2): 393-405. Abstract
• Lei, E.P., Krebber, H., and Silver, P.A. Messenger RNAs are recruited for nuclear export during transcription. Genes Dev. 2001; 15(14): 1771-1782. Abstract
• Brodsky, A.S. and Silver, P.A. Pre-mRNA processing factors are required for nuclear export. RNA 2000; 6(12): 1737-1749.Abstract
• Stage-Zimmermann, T., Schmidt, U. and Silver, P.A. Factors Affecting Nuclear Export of the 60S Ribosomal Subunit In Vivo. Mol Biol Cell 2000 Nov;11(11):3777-3789. Abstract
• Shen, E.C., Stage-Zimmermann, T., Chui, P., and Silver, P.A. The yeast mRNA binding protein Npl3p interacts with the Cap Binding Complex. J. Biol. Chem. 2000 May 22. Abstract

Disease Pathways

• Arbiser, JL, Kau, T., Silver, PA, Bain, J., Bai, X., and Bowen, P. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. 2007. Blood, 109:560

• Frietze, S., Lupien, M., Silver, PA and Brown, N. Coactivator associated arginine methyltransferase CARM1 is required for estrogen stimulated breast cancer growth through regulation of E2F1. 2007. Cancer Research, in press

• Vandegraaff, N., Devroe, E., Turlure, F., Silver, P.A., and Engelman, A. Genetic and biochemical analyses of integrase-interaction proteins lens epithelium-derived growth factor (LEDGF/p75) and hepatoma-derived growth factor 2 (HRP2) in preintegration complex formation and HIV replication. 2006, Virology, in press. Abstract

• Kau, T.R., Schroeder, F., Ramazwamy, S., Wojciechowski, C.L., Zhao, J.J., Roberts, T.M., Clardy, J., Sellers, W.R., and Silver, P.A. A Chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN deficient tumor cells. Cancer Cell. 2003; 4(6):463-76. Abstract
• Haggarty, S.J., Koeller, K.M., Kau, T.R., Silver, P.A., Roberge, M., and Schreiber, S.L. Small molecule modulation of the human chromatid decatenation checkpoint. Chem. Biol. 2003; 10(12):1267-79.

• Kau, T.R., Way, J.C., and Silver, P.A. Nuclear transport and cancer: from mechanism to intervention. Nat. Rev. Cancer. 2004; Feb; 4(2):106-17. Abstract

• Kau, T.R. and Silver, P.A. Nuclear transport as a target for cell growth. Drug Discov. Today. 2003; 8(2):78-85. Abstract

Protein Methylation

• Frietze, S., Lupien, M., Silver, PA and Brown, N. Coactivator associated arginine methyltransferase CARM1 is required for estrogen stimulated breast cancer growth through regulation of E2F1. 2008. Cancer Research, in press.

• Yu, MC, Lamming, DW, Eskin, JA, Sinclair, DA, and Silver, PA. The role of protein arginine methylation in formation of silent chromatin. 2006, Genes and Development, 20:3249-54

• Yu, M.C., Bachand F., McBride, A.E., Komili, S., Casolari, J.M., and Silver, P.A. Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes Dev 2004, Aug. 15. 18(16):2024-35. Abstract

• Weiss, V. H., McBride, A. E., Kim, H. K., Hogle, J. M., and Silver, P. A. The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nat. Struct. Biol. 2000; 7: 1165-1171. Abstract

• Valentini, S.R., Weiss, V.H., and Silver, P.A. Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation. RNA 1999; 5(2):272-80.

Nuclear Transport

• Goffin, L., Vodala, S., Fraser, C., Ryan, J., Timms, M., Meusburger, S., Catimel, B., Nice, EC, Silver, PA., Xiao, CY, Jans, DA., and Gething, MJ. The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. 2006. Mol Bio Cell, 17:5309-5322.

• Robinson, M.A., Park, S., Sun, Z.Y., Silver, P.A., Wagner, G., and Hogle, J.M. Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting domain of Nup116p J. Biol. Chem. 2005. Aug 16. Abstract

• Schroeder, F.C., Kau, T.R., Silver, P.A., and Clardy, J. The psammaplysenes, specific inhibitors of FOXO1a nuclear export. J Nat Prod 2005. Apr; 68(4):574-6. Abstract

• Lu, R., Limon, A., Devroe, E., Cherepanov, P., Silver, P.A., and Engelman, Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a post-nuclear entry step of human immunodeficiency virus type 1 replication. J. Virol. 2004. Dec; 78(23):12735-46.Abstract

• Devroe, E., Engelman, A., and Silver, P.A. Intracellular transport of human immunodeficiency virus type 1 integrase J. Cell. Sci. 2003; 116(Pt21):4401-8. Abstract

• Damelin, M. and Silver, P.A. In situ analysis of spatial relationships between proteins of the nuclear pore complex. Biophys J. 2002; 83(6): 3626-36.Abstract

• Limon A., Devroe, E., Lu, R., Ghory, H.Z., Silver, P.A., and Engelman, A. Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import. J Virol. 2002; 76(21): 10598-607.Abstract

• Hood, J.K., Hwang, W.W., and Silver, P.A. The Saccharomyces cerevisiae cyclin Clb2p is targeted to multiple subcellular locations by cis- and trans-acting determinants. J. Cell Sci. 2001; 114 (3): 589-597. Abstract

• Hood, J.K., Casolari, J.M., and Silver, P.A. Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export. J. Cell Sci. 2000 Apr;113 (Pt 8):1471-80. Abstract
• Jones, A.L., Quimby, B.B., Hood, J.K., Ferrigno, P., Keshava, P.H., Silver, P.A., and Corbett, A.H. SAC3 may link nuclear protein export to cell cycle progression. Proc. Natl. Acad. Sci. USA 2000 Mar 28;97(7):3224-9. Abstract

• Damelin, M. and Silver, P.A. Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex. Mol. Cell 2000; 5: 133-140. Abstract

Membranes and Proteins

• Auld, K., Hitchcock, AL, Doherty, HK, Frietze, S., Huang, LS and Silver PA . A conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae. 2006. Genetics, 174:215-27.

• Beilharz T., Egan, B., Silver, P.A. Hofmann, K., and Lithgow, T. Bipartite signals mediate subcellular targeting of tail-anchored membrane protein in saccharomyces cerevisiae. J. Biol. Chem. 2003; [epub ahead of print].Abstract

• Hitchcock, A.L., Krebber, H., Frietze, S., Lin, A., Latterich, M., and Silver, P.A. The conserved Npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 2001; 12 (10): 3226-3241.

• Prinz, W.A., Grzyb, L., Veenhuis, M., Kahana, J.A., Silver, P.A. and Rapoport, T.A. Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Biol 2000 Aug 7;150(3):461-74. Abstract

Social Commentaries

• Silver, PA. Why do so few women speak at scientific meetings. 2007. Nature 446:85

• Silver. PA. Academic snakes and ladders. 2007. Nature 11:449.