Silver: RNA Dynamics

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===Dynamics of RNAs===
===Dynamics of RNAs===
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The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport. We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level. We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development.
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The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport ([[User: Ian Swinburne |Ian Swinburne]]). We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level in both model organisms (yeast and fly) and human cells, eg ([[User: Natalie Gilks |Natalie Gilks]]) and ([[User: Michael Moore |Michael Moore]]). We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development ([[User: Adrienne McKee |Adrienne McKee]]).  One goal is to decode the way that proteins recognize RNA throughout the genome.

Revision as of 05:36, 19 October 2005

Dynamics of RNAs

The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport (Ian Swinburne). We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level in both model organisms (yeast and fly) and human cells, eg (Natalie Gilks) and (Michael Moore). We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development (Adrienne McKee). One goal is to decode the way that proteins recognize RNA throughout the genome.

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