Silver: Synthetic Biology Review Article
David Drubin and Pam Silver are writing an in depth review article on Synthetic Biology for Genes and Development. We would very much like input from the community. Please post any suggestions or papers that you would like us to talk about here. Thanks!
It would be helpful if you could provide us with some framing thoughts for how you will structure your article. It's not clear how much input you want from OWW users. For example, should we write the article on OWW, and have a continuous live in depth review of the field or are you going in a particular direction? Thanks! Endy 12:26, 16 June 2006 (EDT)
artificial vesicle based biology
- Noireaux V, Bar-Ziv R, Godefroy J, Salman H, and Libchaber A. Toward an artificial cell based on gene expression in vesicles. Phys Biol. 2005 Sep 15;2(3):P1-8. DOI:10.1088/1478-3975/2/3/P01 |
- Noireaux V and Libchaber A. A vesicle bioreactor as a step toward an artificial cell assembly. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17669-74. DOI:10.1073/pnas.0408236101 |
- Chen IA, Roberts RW, and Szostak JW. The emergence of competition between model protocells. Science. 2004 Sep 3;305(5689):1474-6. DOI:10.1126/science.1100757 |
Mathematical or Quantitative (Predictive) Models of Gene Networks
- Tuttle LM, Salis H, Tomshine J, and Kaznessis YN. Model-driven designs of an oscillating gene network. Biophys J. 2005 Dec;89(6):3873-83. DOI:10.1529/biophysj.105.064204 |
materials for teaching undergrads
Beyond iGEM, there are some initial teaching efforts from courses taught at
UC Berkeley [[1]]
and at MIT [[2]] and [[3]]. Some of the MIT material was adapted as iGEM 06 teaching material at BU [[4]] so it didn't take long for the use of even a fledgling curriculum effort to spread.
Hopefully, as Synthetic Biology advances, the research will provide examples and technologies that capture the distinguishing aspects of the field. It would be great if teaching materials could be developed in parallel to rigorously educate a larger number students who might later do this work. Perhaps somewhere in your review there could be an explicit call for curriculum development as well. - Natalie
other ideas
- I think it would be nice to see where Systems Biology meets Synthetic Biology, e.g the use of modeling tools in synthetic biology.
