Smolke:Journal Club

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Next Meeting When: Where: Paper: Moderator: Suggested Future Papers Ray PS, Jia J, Yao P, Majumder M, Hatzoglou M, and Fox PL. A stress-responsive RNA switch regulates VEGFA expression. Nature. 2009 Feb 12;457(7231):915-9. DOI:10.1038/nature07598 | Runguphan W and O'Connor SE. Metabolic reprogramming of periwinkle plant culture. Nat Chem Biol. 2009 Mar;5(3):151-3. DOI:10.1038/nchembio.141 | Ham TS, Lee SK, Keasling JD, and Arkin AP. Design and construction of a double inversion recombination switch for heritable sequential genetic memory. PLoS One. 2008 Jul 30;3(7):e2815. DOI:10.1371/journal.pone.0002815 | Yu RC, Pesce CG, Colman-Lerner A, Lok L, Pincus D, Serra E, Holl M, Benjamin K, Gordon A, and Brent R. Negative feedback that improves information transmission in yeast signalling. Nature. 2008 Dec 11;456(7223):755-61. DOI:10.1038/nature07513 | Comments on Papers I found the Ham et al. [3] paper extremely disappointing. If you want an example of what not to do, it's a good one. But otherwise I'd skip it. -Josh I suggested the Ham et al. [3] mostly to throw out a paper about synthetic information processing in cells. It is outside my area of familiarity, but I think it could be interesting, especially since that is what the Endy lab is gearing up to attack. So if anyone else has a good recent paper on some synthetic biology approach to information processing, I think that might be cool for us to read and critique. -Mike