Publications
Reviewed Journal Publications
- Hawkins KM and Smolke CD. The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae. J Biol Chem. 2006 May 12;281(19):13485-13492. DOI:10.1074/jbc.M512317200 | PubMed ID:16524886 | HubMed [hawkins]
- Pfleger BF, Pitera DJ, Smolke CD, and Keasling JD. Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat Biotechnol. 2006 Aug;24(8):1027-32. DOI:10.1038/nbt1226 | PubMed ID:16845378 | HubMed [pfleger]
- Bayer TS and Smolke CD. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat Biotechnol. 2005 Mar;23(3):337-43. DOI:10.1038/nbt1069 | PubMed ID:15723047 | HubMed [bayer]
- Isaacs FJ and Collins JJ. Plug-and-play with RNA. Nat Biotechnol. 2005 Mar;23(3):306-7. DOI:10.1038/nbt0305-306 | PubMed ID:15765083 | HubMed [isaacs]
- Smolke CD and Keasling JD. Effect of gene location, mRNA secondary structures, and RNase sites on expression of two genes in an engineered operon. Biotechnol Bioeng. 2002 Dec 30;80(7):762-76. DOI:10.1002/bit.10434 | PubMed ID:12402322 | HubMed [smolke1]
- Smolke CD and Keasling JD. Effect of copy number and mRNA processing and stabilization on transcript and protein levels from an engineered dual-gene operon. Biotechnol Bioeng. 2002 May 20;78(4):412-24. DOI:10.1002/bit.10218 | PubMed ID:11948448 | HubMed [smolke2]
- Smolke CD, Khlebnikov A, and Keasling JD. Effects of transcription induction homogeneity and transcript stability on expression of two genes in a constructed operon. Appl Microbiol Biotechnol. 2001 Dec;57(5-6):689-96. DOI:10.1007/s002530100812 | PubMed ID:11778879 | HubMed [smolke3]
- Smolke CD, Martin VJ, and Keasling JD. Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization. Metab Eng. 2001 Oct;3(4):313-21. DOI:10.1006/mben.2001.0194 | PubMed ID:11676567 | HubMed [smolke4]
- Smolke CD, Carrier TA, and Keasling JD. Coordinated, differential expression of two genes through directed mRNA cleavage and stabilization by secondary structures. Appl Environ Microbiol. 2000 Dec;66(12):5399-405. DOI:10.1128/AEM.66.12.5399-5405.2000 | PubMed ID:11097920 | HubMed [smolke5]
All Medline abstracts: PubMed | HubMed
- Win, M.N., Klein, J.S., Smolke, C.D. (2006) RNA aptamers to the benzylisoquinoline alkaloid codeine and the rapid characterization of their binding properties using surface plasmon resonance. In submission.
Non-Peer-Reviewed Publications
- Bayer, T.S., Smolke, C.D. (2006) Design of nucleic acid switches. Nature Protocols. In preparation.
- Baker, D., Church, G., Collins, J., Endy, D., Jacobson, J., Keasling, J., Modrich, P., Smolke, C., Weiss, R. (2006) Engineering Life: Building a Fab for Biology. Scientific American June issue.
- Smolke, C. 2005. Molecular switches for cellular sensors. Engineering and Applied Science 4, 28-37
- Martin, V.J.J., Smolke, C.D., Keasling, J.D. (2002) Redesigning cells for the production of complex organic molecules. ASM News 68, 336-343.
Books and Book Chapters
- Smolke, C.D., editor (2006) Metabolic Engineering Protocols: Synthesis and Design Strategies. In: Walker J, series ed., Methods in Molecular Biology. Totawa: Humana Press. In preparation.
- Smolke, C.D., editor (2006) Metabolic Engineering Protocols: Analysis and Characterization. In: Walker J, series ed., Methods in Molecular Biology. Totawa: Humana Press. In preparation.
- Smolke, C.D., editor (2006) Handbook for Metabolic Pathway Engineering. San Diego: CRC Press. In preparation.
- Smolke, C.D., Martin, V.J.J., Keasling, J.D. (2004) Tools for metabolic engineering in Escherichia coli. In: Baneyx, F., editor. Expression Technologies. U.K.: Horizon Scientific Press.
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