We are interested in deciphering signaling pathways that contribute to the maintenance of genomic stability in our cells. We are specifically investigating DNA repair pathways that are activated during the S-phase of the cell cycle when chromosomes replicate.
Our current focus are the Fanconi Anemia (FA) and Breast Cancer associated (BRCA1, BRCA2) repair pathways that are suspected to act at the crossroads of DNA replication, repair, and cell cycle checkpoint activation. Our lab uses Xenopus laevis cell-free egg extracts that are naturally cell-cycle synchronized and replication competent to study roles of FA and BRCA pathway members during the DNA damage response.
- Current rotation student and moose whisperer: Jordan Becker
- Upcoming BMBB retreat at the Minnesota Landscape Arboretum: OCTOBER 16. Posters from our lab will be presented by Archana Sareen, PhD and Indrajit Chaudhury, PhD
!! Mark your calendars for the Fanconi Anemia Research Fund Symposium from Oct 21-24 here in downtown Minneapolis !!