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Xenopus laevis
Principle Investigator
Alex Sobeck , PI
Current Funding:
2011 - 2014 National Science Foundation
2010 - 2012 Minnesota Medical Foundation
2011 - 2012 Masonic Cancer Center, Translational Breast Cancer Research Award
2011 - 2013 Masonic Cancer Center, Leukemia Research Fund
2012 - 2014 University of Minnesota Grant in Aid
Lab Members
Indrajit Chaudhury , Postdoctoral Fellow; Indrajit is studying the functional connection between FA core complex, FANCD2/FANCI and the BLM helicase pathway during normal and perturbed replication. IC is currently funded by the American Heart Association with a 2-year postdoctoral fellowship.
Archana Sareen , Postdoctoral Fellow; Archana focuses on deciphering the molecular functions of two core FA proteins, FANCD2 and FANCI, during the DNA damage response.
Maya Raghunandan , Graduate Student; Maya is interested in deciphering how direct protein-protein interactions between FA pathway members and other DNA repair proteins regulate the DNA damage response. Real photo coming soon...
Nicki Adams , Junior Scientist; Nicky is generating and testing FA protein mutants for functional defects in our Xenopus egg extract system.
Rose Kantor , Junior Scientist; Rose is fishing for Xenopus homologs of human FA and FA-related genes. She uses regular PCR and RACE-PCR to clone new Xenopus genes
Charlene Fares , Directed Research Student; Charlene is investigating interactions between the FA pathway and the non-homologous recombination repair (NHEJ) machinery.
Brittany Feia , Work Study Student; Britt takes care of organizational issues on the lab and helps us with cloning and antibody characterizations.