Spectinomycin
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Mode of Action
Spectinomycin is a bacteriostatic agent that inhibits translocation of the peptidyl tRNA from the A site to the P site.
Working Concentrations and Stock Solutions
Up to 100mg/mL stock concentration. 100ug/mL final concentration.
Resistance Gene
Mutations in rpsE, the S5 protein, prevent spectinomycin from binding.