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==AML Project==
==AML Project==


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== Purpose ==
== Purpose ==
To understand the behavior of signaling mechanism in hematopoietic disorders, in particular Acute Myelogenous Leukemia (AML) using Complex Systems Biology and a data rich flow cytometry approach.
To understand the behavior of the signaling mechanism in hematopoietic disorders, in particular Acute Myelogenous Leukemia (AML) using Complex Systems Biology and a data rich flow cytometry approach.
 


== Meeting ==
The AML Systems Biology group meets every Friday, with alternating locations in the Wolstein conference room (WRB 3-522) and the OLIN conference room (OLIN 408). Meeting time in WRB is 9:00 to 10:00 am, while meeting time in OLIN is 9:30 to 10:30 am.


== Participants ==
== Participants ==
Professor James 'Jake' Jacobberger (Hematology/Oncology)


Sree N. Sreenath (Electrical Engineering and Computer Science)
'''Faculty & Staff'''
 
Professor James 'Jake' Jacobberger (Hematology/Oncology), Director of the Cytometry Core Facility


R. Michael Sramkoski
Professor Sree N. Sreenath (Electrical Engineering and Computer Science)


Yehong Huong
R. Michael Sramkoski, Manager of the Cytometry Core Facility


Radina P. Soebiyanto


Michael C. Weis
'''Students'''
 
'''''Graduate'''''


Jayant Avva
Jayant Avva


Arielle Kanters
Yehong Huong (Jacobberger Lab)
 
Radina P. Soebiyanto


Akshai Singh
Michael C. Weis


== Papers being discussed ==


Disruption of Differentiation in Human Cancer: AML Shows the Way
Daniel Tenen


The Role of FLT3 in Hematopoietic Malignancies
'''''Undergraduate'''''
Derek L. Stirewalt and Jerald P. Radich


Cross-talk and decision making in MAP kinase pathways
Arielle Kanters
Megan N McClean, Areez Mody, James R Broach and Sharad Ramanathan


Compartmental Architecture and Dynamics of Hematopoiesis
Akshai Singh
David Dingli, Arne Taulsen, Jorge M. Pacheco

Latest revision as of 16:12, 17 May 2007

CASE Complex Systems Biology Center

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AML Project

Purpose

To understand the behavior of the signaling mechanism in hematopoietic disorders, in particular Acute Myelogenous Leukemia (AML) using Complex Systems Biology and a data rich flow cytometry approach.


Participants

Faculty & Staff

Professor James 'Jake' Jacobberger (Hematology/Oncology), Director of the Cytometry Core Facility

Professor Sree N. Sreenath (Electrical Engineering and Computer Science)

R. Michael Sramkoski, Manager of the Cytometry Core Facility


Students

Graduate

Jayant Avva

Yehong Huong (Jacobberger Lab)

Radina P. Soebiyanto

Michael C. Weis


Undergraduate

Arielle Kanters

Akshai Singh

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