Sriram Kosuri
Personal
Bio
I am curently a postdoc in George Church's lab in the Department of Genetics at Harvard Medical School and the Wyss Institute. From September 2007 to February 2009, I worked at a small Cambridge-area startup called Joule Unlimited. I am also on the Board of Directors for OpenWetWare. I previously did a short postdoctoral stint in Mike Laub's lab working on cell cycle in Caulobacter crescentus. Prior to the Laub lab, I was a graduate student in Drew Endy's lab and worked on understanding the development of a simple virus (T7) that infects E. coli. As an undergraduate at UC Berkeley, I worked with Adam Arkin, Dale Kaiser, and Roy Welch on modeling traveling wave formation in M. xanthus.
Science
Publications
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
Feng Zhang, Le Cong, Simona Lodato, Sriram Kosuri, George Church & Paola Arlotta
Nature Biotechnology (2011) doi:10.1038/nbt.1775
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
Sriram Kosuri, Nikolai Eroshenko, Emily LeProust, Michael Super, Jeffrey Way, Jin Billy Li & George Church
Nature Biotechnology (2010) 28:1295 doi:10.1038/nbt.1716
News & Views, Cover Art
TABASCO: A single molecule, base-pair resolved gene expression simulator
Sriram Kosuri, Jason Kelly and Drew Endy
BMC Bioinformatics 2007, 8:480 doi:10.1186/1471-2105-8-480
URL
Refactoring bacteriophage T7
Leon Y. Chan, Sriram Kosuri and Drew Endy
Molecular Systems Biology 13 September 2005 DOI:10.1038/msb4100025
URL
PDF reprint
News & Views
October 2004 version
Interests
- Developing technologies on making biology easier to engineer.
- Enabling the design, construction, and use of biological organisms for the purposes of further scientific understanding; keeping extremely aware of the use of engineered biological organisms for other purposes.
- Understanding those aspects of biological design that allow for certain robust features of development in the face of large intrinsic and extrinsic variation specifically on non-evolutionary time-scales (I am currently giving up on the past. That may change in the future.).
- Property rights as related to biological information and organisms; understanding and reforming current and future frameworks; I really like these people
- OpenWetWare of course!
Past Projects
TABASCO -- A single molecule base-pair resolved gene expression simulator
Measure and Models of T7 Infection
How does T7 deal with Uncertainty
Interesting Stuff
The beginnings of a blog.
See my interesting stuff page
A failed Research Plan for a job at Harvard's CGR
Contact
Phone: still waiting
OWW users: Post a message on my talk page, or send me an email.
Email: 
Postal:
Harvard Medical School
Genetics Department
New Research Building (NRB) Rooms 232
77 Ave. Louis Pasteur
Boston, MA 02115 USA
Who's Visiting
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