Stacie Stone

Contact: stonest@ohsu.edu

Research

The Fanconi Anemia pathway

Publications

1. Sobeck, A., Stone, S. Costanzo, V., de Graaf, B., Reuter, T. de Winter, J., Wallisch, M., Akkari, Y., Olson, S., Wang, W., Joenje, H., Christian, J., Lupardus, P. L., Cimprich, K.A., Gautier, J., and Hoatlin, M. E. Fanconi Anemia Proteins are Required to Prevent Accumulation of Replication-Associated DNA Double Strand Breaks. Mol Cell Biol. 2006 Jan;26(2):425-37. abstract PDF reprint This paper describes the first use of the Xenopus extract system for Fanconi proteins, including cloning of several of the Xenopus FA homologs
2. Meetei AR, Medhurst AL, Ling C, Xue Y, Singh TR, Bier P, Steltenpool J, Stone S , Dokal I, Mathew CG, Hoatlin M, Joenje H, de Winter JP, Wang W. A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet. 2005, 37(9):958-63. abstract Highlighted by Faculty of 1000
3. Dai MS, Chevallier N, Stone S, Heinrich MC, McConnell M, Reuter T, Broxmeyer HE, Licht JD, Lu L, Hoatlin ME. The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. J Biol Chem. 2002 Jul 19;277(29):26327-34. abstract
4. van de Vrugt HJ, Koomen M, Berns MA, de Vries Y, Rooimans MA, van der Weel L, Blom E, de Groot J, Schepers RJ, Stone S, Hoatlin ME, Cheng NC, Joenje H, Arwert F. Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg. Genes Cells. 2002 Mar;7(3):333-42. abstract
5. de Winter JP, van der Weel L, de Groot J, Stone S, Waisfisz Q, Arwert F, Scheper RJ, Kruyt FA, Hoatlin ME, Joenje H. The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG. Hum Mol Genet. 2000 Nov 1;9(18):2665-74. abstract
6. Heinrich MC, Silvey KV, Stone S, Zigler AJ, Griffith DJ, Montalto M, Chai L, Zhi Y, Hoatlin ME. Posttranscriptional cell cycle-dependent regulation of human FANCC expression. Blood. 2000 Jun 15;95(12):3970-7. abstract
7. Hoatlin ME, Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, Licht JD. A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF. Blood. 1999 Dec 1;94(11):3737-47. abstract Describes the cloning of FAZF

Abstracts

FA Research Symposium, Houston, Texas 2003

• FA Research Symposium, Geneva, Switzerland 2005

• FA Research Symposium, Cambridge, Massachusetts 2004

• Ventura, California 2003

• FA Research Symposium, Houston, Texas 2003

• Ash 2003

• FA Research Symposium, Portland, Oregon 2001

Visiting Student

• 2003 Visiting Scientist, Free University of Amsterdam, The Netherlands Laboratory of Dr. Hans Joenje

• 2005 Visiting Scientist, National Institute of Health, Baltimore, Maryland Laboratory of Dr. Weidong Wang

Education

• 2003-present Ph.D. candidate: Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands (Dr Maureen Hoatlin and Dr. Hans Joenje)
• B.S. in Molecular Biology/Biotechnology, Portland State University 2000

Hobbies

• Dodgeball, Bowling, Snowboarding, Golf, Fishing, and Soccer.

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