Stephanopoulos:Projects

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Current revision (18:30, 17 July 2007) (view source)
 
(3 intermediate revisions not shown.)
Line 8: Line 8:
|height=6px|
|height=6px|
|-
|-
-
|style="border: 3px solid maroon; padding:15px; background-color: #FFCCAA;"|
+
|style="padding:15px; background-color: #EED0BB;"|
= <font style="color:maroon">Research</font> =
= <font style="color:maroon">Research</font> =
Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:
Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:
-
:* '''The modification of biochemical pathways inside cells''', and
+
# '''The modification of biochemical pathways inside cells''', and
-
:* '''The rigorous evaluation of the resulting cellular phenotypes.'''
+
# '''The rigorous evaluation of the resulting cellular phenotypes.'''
   
   
Our most recent research has been focused on the following topics:
Our most recent research has been focused on the following topics:
-
:* [[Stephanopoulos Lab:Production of biochemicals in E. coli | '''Metabolic Engineering of <i>E.Coli</i> for the production of biochemicals''']]
+
:* [[Stephanopoulos:Production of biochemicals in E. coli | '''Metabolic Engineering of <i>E.Coli</i> for the production of biochemicals''']]
-
:* [[Stephanopoulos Lab:Inverse Metabolic Engineering | '''Inverse Metabolic Engineering''']]
+
:* [[Stephanopoulos:Inverse Metabolic Engineering | '''Inverse Metabolic Engineering''']]
-
:* [[Stephanopoulos Lab:gTME | '''gTME''']]
+
:* [[Stephanopoulos:gTME | '''gTME''']]
-
:* [[Stephanopoulos Lab:Flux Determination | '''Flux Determination''']]
+
:* [[Stephanopoulos:Flux Determination | '''Flux Determination''']]
-
:* [[Stephanopoulos Lab:Hepatocyte Physiology | '''Hepatocyte Physiology''']]
+
:* [[Stephanopoulos:Hepatocyte Physiology | '''Hepatocyte Physiology''']]
-
:* [[Stephanopoulos Lab:Metabolomics | '''Metabolomics''']]
+
:* [[Stephanopoulos:Metabolomics | '''Metabolomics''']]
-
:* [[Stephanopoulos Lab:Rational Drug Design | '''Rational Drug Design''']]
+
:* [[Stephanopoulos:Rational Drug Design | '''Rational Drug Design''']]
-
:* [[Stephanopoulos Lab:Systems Biology | '''Systems Biology''']]
+
:* [[Stephanopoulos:Systems Biology | '''Systems Biology''']]
Line 39: Line 39:
methods, many of which have also become areas of research for our group:
methods, many of which have also become areas of research for our group:
-
:* [[Stephanopoulos Lab:Bioinformatics and Systems Biology | '''Bioinformatics and Systems Biology''']] - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies.
+
:* [[Stephanopoulos:Bioinformatics and Systems Biology | '''Bioinformatics and Systems Biology''']] - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies.
-
:* [[Stephanopoulos Lab:Methods for intracellular flux determination | '''Methods for intracellular flux determination''']] - Fluxes are determined by material balancing, NMR fine spectra analysis and GC-MS measurements.
+
:* [[Stephanopoulos:Methods for intracellular flux determination | '''Methods for intracellular flux determination''']] - Fluxes are determined by material balancing, NMR fine spectra analysis and GC-MS measurements.
-
:* [[Stephanopoulos Lab:DNA microarrays | '''DNA microarrays''']] - We have developed full genome microarrays for ''Synechocystis'' Sp., and partial microarrays for ''C. glutamicum'', ''E. coli'', and the mouse genomes.  
+
:* [[Stephanopoulos:DNA microarrays | '''DNA microarrays''']] - We have developed full genome microarrays for ''Synechocystis'' Sp., and partial microarrays for ''C. glutamicum'', ''E. coli'', and the mouse genomes.  
-
:* [[Stephanopoulos Lab:Bioreaction network analysis | '''Bioreaction network analysis''']]
+
:* [[Stephanopoulos:Bioreaction network analysis | '''Bioreaction network analysis''']]
|}
|}
{{Template:Stephanopoulos_bamel_middle}}
{{Template:Stephanopoulos_bamel_middle}}
-
{{Template:Stephanopoulos_bamel_bottom}}
 

Current revision

Stephanopoulos Lab logo

Home
News
People
Research
Publications
Software
Courses
Data Sets
Opportunities
changing picture

Research

Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:

  1. The modification of biochemical pathways inside cells, and
  2. The rigorous evaluation of the resulting cellular phenotypes.


Our most recent research has been focused on the following topics:


To accomplish the above goals we make use of a diverse array of scientific tools and methods, many of which have also become areas of research for our group:

  • Bioinformatics and Systems Biology - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies.
  • DNA microarrays - We have developed full genome microarrays for Synechocystis Sp., and partial microarrays for C. glutamicum, E. coli, and the mouse genomes.

Image:Ban_2_dsm.gif

Personal tools